Current Research in Structural Biology

Scope & Guideline

Advancing the Frontiers of Structural Biology

Introduction

Welcome to the Current Research in Structural Biology information hub, where our guidelines provide a wealth of knowledge about the journal’s focus and academic contributions. This page includes an extensive look at the aims and scope of Current Research in Structural Biology, highlighting trending and emerging areas of study. We also examine declining topics to offer insight into academic interest shifts. Our curated list of highly cited topics and recent publications is part of our effort to guide scholars, using these guidelines to stay ahead in their research endeavors.
LanguageEnglish
ISSN-
PublisherELSEVIER
Support Open AccessNo
Country-
Type-
Converge-
AbbreviationCURR RES STRUCT BIOL / Curr. Res. Struct. Biol.
Frequency1 issue/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
AddressRADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS

Aims and Scopes

The journal 'Current Research in Structural Biology' aims to provide a platform for cutting-edge research in the field of structural biology, focusing on the intricate relationships between molecular structures and biological functions. It covers a broad range of topics that combine experimental and computational methodologies to elucidate the structure-function relationships in biological macromolecules.
  1. Structural Analysis of Proteins and Complexes:
    The journal emphasizes the detailed structural analysis of proteins, including their conformational dynamics and interactions, which are essential for understanding their biological roles.
  2. Computational Modeling and Bioinformatics:
    A significant focus is placed on computational approaches, including molecular modeling, simulations, and bioinformatics tools, to predict and analyze protein structures and their interactions.
  3. Drug Discovery and Pharmacology:
    Research related to drug design, mechanisms of drug action, and the structural basis for drug resistance is a core area, highlighting the journal's relevance to pharmaceutical sciences.
  4. Innovative Experimental Techniques:
    The journal showcases novel experimental methodologies such as cryo-electron microscopy, X-ray crystallography, and NMR spectroscopy, which are pivotal in structural biology research.
  5. Functional Characterization of Biomolecules:
    There is a consistent focus on the functional implications of structural findings, linking protein structures to their biological activities and potential therapeutic applications.
Recent publications in 'Current Research in Structural Biology' reveal several emerging themes that highlight the journal's responsiveness to contemporary challenges and advancements in the field. These trends indicate a growing interest in interdisciplinary approaches and the application of structural biology in various contexts.
  1. Structural Biology in Drug Development:
    There is a notable increase in publications focusing on using structural insights for drug discovery, particularly in the context of viral diseases like COVID-19, showcasing the journal's relevance in pharmacological research.
  2. Integrative Structural Biology:
    Emerging themes include integrative approaches that combine multiple structural techniques (e.g., cryo-EM and crystallography) to provide comprehensive insights into biomolecular structures and functions.
  3. Dynamic and Functional Studies:
    An increasing number of studies are exploring the dynamics of protein interactions and conformational changes, emphasizing the importance of understanding proteins in their functional states.
  4. Bioinformatics and Machine Learning Applications:
    The rise of bioinformatics tools and machine learning techniques for predicting protein interactions and structures reflects a growing trend towards computational methods that complement experimental work.
  5. Environmental and Extremophilic Research:
    Recent interest in the structural adaptations of extremophiles and their potential applications in biotechnology suggests a trend towards understanding life in extreme conditions.

Declining or Waning

While 'Current Research in Structural Biology' maintains a strong emphasis on various aspects of structural biology, certain themes appear to be declining in prominence. This reflects the journal's evolving focus as new methodologies and research questions emerge in the field.
  1. Traditional Structural Biology Approaches:
    There seems to be a waning interest in purely traditional structural biology approaches, such as basic crystallography studies without a clear connection to biological function or drug design.
  2. Static Structural Analysis:
    Research that focuses solely on static structural analyses of proteins without considering dynamics or interactions is becoming less common, as the field increasingly values dynamic and functional insights.
  3. Basic Biochemical Characterization:
    Papers that primarily provide biochemical characterization without integrating structural insights or computational modeling are less frequently published, indicating a shift towards more integrative studies.

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