ACS Bio & Med Chem Au
Scope & Guideline
Advancing the frontiers of biochemistry and medicinal chemistry.
Introduction
Aims and Scopes
- Biological Chemistry and Drug Design:
The journal emphasizes the design and synthesis of biologically active compounds, including small molecules and peptides, aimed at therapeutic applications. - Catalysis and Mechanistic Studies:
Research on catalytic mechanisms and the role of enzymes in biological processes is a core theme, including investigations into RNase families and protease inhibitors. - Biotechnology and Bioengineering:
The journal publishes studies on biotechnological applications, such as the development of bioproduction platforms and functionalized biomaterials for medical use. - Structural Biology and Imaging Techniques:
Studies utilizing advanced imaging techniques and structural biology to elucidate the interactions of biomolecules and their mechanisms of action are prominently featured. - Nanotechnology and Biomaterials:
Research on the development of nanocarriers and materials for drug delivery, as well as the exploration of their biological interactions, is a significant focus area. - Bioinformatics and Computational Chemistry:
The integration of computational methods to understand biological processes and predict the interactions of compounds with biological targets is a growing area of interest.
Trending and Emerging
- Targeted Protein Degradation:
Research on targeted protein degradation techniques, such as the use of heterobifunctional degraders, is on the rise, reflecting a growing interest in innovative therapeutic strategies. - Synthetic Biology and Bioconjugation:
There is an increasing trend in studies involving synthetic biology approaches, particularly in the design and engineering of peptide ligands and bioconjugates for therapeutic applications. - Immunotherapy and Antibody Development:
The journal has seen a surge in papers focused on immunotherapeutic strategies, including the development of antibody-based therapies and their mechanisms of action. - Antiviral Agents and COVID-19 Research:
In light of the recent pandemic, there is a notable increase in research related to antiviral agents and their mechanisms, particularly studies aimed at combating SARS-CoV-2. - Nanomedicine and Drug Delivery Systems:
Emerging themes in nanomedicine, particularly regarding the development of nanocarriers for drug delivery and their interactions in biological systems, are increasingly prevalent.
Declining or Waning
- Traditional Antibiotics and Resistance Mechanisms:
Research focused on traditional antibiotics and their mechanisms of action appears to be waning, possibly due to the shift towards exploring novel antimicrobial strategies and resistance mechanisms. - Basic Biochemical Pathways:
There has been a noticeable decline in publications centered on fundamental biochemical pathways, as the journal shifts towards more applied research with immediate clinical implications. - Natural Products Chemistry:
The exploration of natural products as a source of therapeutic agents seems to be less frequent, possibly overshadowed by synthetic and engineered compounds with targeted actions. - General Reviews on Established Topics:
The publication of broad review articles on well-established topics is decreasing, indicating a preference for more specialized and cutting-edge reviews that focus on emerging areas.
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