DEVELOPMENTAL CELL

Scope & Guideline

Advancing Knowledge in Developmental Biology

Introduction

Welcome to your portal for understanding DEVELOPMENTAL CELL, featuring guidelines for its aims and scope. Our guidelines cover trending and emerging topics, identifying the forefront of research. Additionally, we track declining topics, offering insights into areas experiencing reduced scholarly attention. Key highlights include highly cited topics and recently published papers, curated within these guidelines to assist you in navigating influential academic dialogues.
LanguageEnglish
ISSN1534-5807
PublisherCELL PRESS
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 2001 to 2024
AbbreviationDEV CELL / Dev. Cell
Frequency12 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address50 HAMPSHIRE ST, FLOOR 5, CAMBRIDGE, MA 02139

Aims and Scopes

The journal 'Developmental Cell' focuses on the cellular and molecular mechanisms underlying development, regeneration, and disease, with a strong emphasis on the dynamic processes that govern cell behavior and fate decisions. The journal covers a wide range of topics, integrating various biological disciplines to provide a comprehensive understanding of development at the cellular level.
  1. Cellular Dynamics in Development:
    Research exploring how cellular processes and interactions shape developmental outcomes, including cell signaling, migration, and differentiation.
  2. Mechanisms of Regeneration:
    Studies focused on the molecular and cellular mechanisms that enable regeneration in various organisms, shedding light on potential therapeutic approaches for human tissue repair.
  3. Stem Cell Biology:
    Investigation of the properties and behaviors of stem cells, including their differentiation pathways, niche interactions, and roles in development and disease.
  4. Epigenetics and Gene Regulation:
    Research examining the epigenetic modifications and transcriptional regulatory mechanisms that influence development and cellular identity.
  5. Model Organisms in Developmental Biology:
    Utilization of various model organisms, such as zebrafish, Drosophila, and mice, to gain insights into developmental processes and their underlying mechanisms.
  6. Cell-Extracellular Matrix Interactions:
    Studies that investigate how cells interact with their extracellular matrix and how these interactions influence cell behavior and tissue morphogenesis.
  7. Pathophysiology and Disease Mechanisms:
    Exploration of the developmental basis of diseases, including cancer, and how developmental processes may be exploited for therapeutic purposes.
The journal has seen an increase in focus on several emerging themes that reflect the current trends in developmental biology, particularly in response to advancements in technology and changing research interests.
  1. Single-Cell Genomics and Transcriptomics:
    Recent publications emphasize the use of single-cell technologies to dissect cellular heterogeneity and understand developmental trajectories at unprecedented resolution.
  2. Mechanobiology:
    Research increasingly explores how mechanical forces influence cellular behavior, development, and disease processes, highlighting the interplay between physical and biological systems.
  3. Intercellular Communication:
    There is a growing interest in understanding the mechanisms and roles of intercellular signaling and communication in coordinating developmental processes and tissue homeostasis.
  4. Phase Separation and Biomolecular Condensates:
    Emerging studies focus on the role of phase separation and the formation of biomolecular condensates in cellular organization and function, particularly in response to stress.
  5. Regenerative Medicine and Stem Cell Applications:
    There is a notable trend towards translating basic research findings into regenerative medicine applications, with an emphasis on stem cell therapies and tissue engineering.
  6. Environmental and Nutritional Influences on Development:
    Research increasingly highlights the impact of environmental factors and nutrition on developmental processes, emphasizing the importance of context in shaping cellular outcomes.

Declining or Waning

While 'Developmental Cell' has a broad and evolving scope, certain themes have shown a decline in focus over the years, possibly due to shifts in research priorities or emerging technologies that overshadow previous interests.
  1. Classical Developmental Genetics:
    Studies that traditionally focused on genetic mutations affecting development have waned as newer technologies, like single-cell sequencing, allow for more intricate analyses of cellular dynamics.
  2. Static Models of Development:
    Research using static or less dynamic models of development is becoming less prevalent as the field increasingly prioritizes real-time imaging and dynamic modeling approaches.
  3. Reductionist Approaches:
    There has been a decline in purely reductionist approaches to studying development, with a growing emphasis on systems biology and integrative methods that consider multiple layers of biological organization.
  4. In Vitro Models:
    While still important, there has been a relative decline in the use of traditional in vitro models, as researchers favor more complex in vivo models or organoid systems that better mimic physiological conditions.
  5. Focus on Individual Cell Types:
    The trend has shifted away from studying individual cell types in isolation toward understanding cell interactions and the context of cellular behavior in multicellular systems.

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