GENES TO CELLS
Scope & Guideline
Advancing Knowledge from Genes to Cellular Function
Introduction
Aims and Scopes
- Molecular Mechanisms of Cellular Processes:
Research exploring the molecular pathways that govern cellular functions, including signaling pathways, gene regulation, and interactions between proteins and nucleic acids. - Genetic and Epigenetic Regulation:
Studies focusing on how genetic and epigenetic modifications influence gene expression, cellular behavior, and developmental processes. - Cellular Responses to Environmental Stimuli:
Investigations into how cells adapt to various physiological and pathological conditions, including stress responses, aging, and disease mechanisms. - Stem Cell Biology and Development:
Research on the mechanisms of stem cell differentiation and development, including the role of specific genes and signaling pathways in cell fate determination. - Cancer Biology and Therapeutics:
Papers addressing the genetic and molecular basis of cancer, exploring potential therapeutic strategies and the role of tumor microenvironment. - Model Organisms in Biological Research:
Utilization of various model organisms, such as yeast, mice, and plants, to elucidate fundamental biological processes and gene functions.
Trending and Emerging
- Multi-Omics Approaches:
There is an increasing trend in the application of multi-omics techniques (genomics, transcriptomics, proteomics, etc.) to provide comprehensive insights into cellular functions and disease mechanisms. - Mechanobiology and Cellular Mechanics:
Research focusing on the physical properties of cells and how mechanical forces influence cellular behavior and gene expression is on the rise, emphasizing the interplay between physical and biological sciences. - Advancements in Gene Editing Technologies:
The use of CRISPR and other gene-editing technologies is becoming more prominent, with studies exploring innovative applications in functional genomics and therapeutic interventions. - Immunology and Inflammation Research:
There is a notable increase in studies investigating the role of the immune system in health and disease, particularly regarding how cellular interactions and signaling pathways modulate immune responses. - Neurobiology and Cellular Dynamics:
Emerging research in neurobiology, particularly studies examining neuronal cell dynamics and their implications for understanding neurodegenerative diseases, is gaining increased attention.
Declining or Waning
- Basic Studies of Classical Genetics:
There appears to be a waning interest in traditional genetic studies that do not incorporate modern techniques or insights from molecular biology and genomics. - Overly Broad or Generalized Research Topics:
Papers that focus on overly broad themes without specific experimental approaches or novel insights are becoming less prevalent, as the journal shifts towards more targeted and impactful studies. - Single-Cell Analysis Techniques:
Although still relevant, publications focused solely on single-cell analyses, without integrating findings into broader biological contexts, are decreasing as researchers seek to connect single-cell findings to tissue or organism-level implications.
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