eLife
Scope & Guideline
Pioneering Open Access in Biological Research
Introduction
Aims and Scopes
- Multidisciplinary Biological Research:
eLife publishes research across various disciplines in biology, including molecular biology, genetics, neuroscience, and ecology, which facilitates interdisciplinary collaboration and knowledge exchange. - Innovative Methodologies:
The journal emphasizes the use of cutting-edge methodologies, including advanced imaging techniques, computational modeling, and high-throughput sequencing, to address complex biological questions. - Open Science and Transparency:
eLife promotes open science practices, encouraging data sharing, reproducibility, and transparency in research, which enhances the credibility and accessibility of scientific findings. - Focus on Mechanisms and Processes:
Articles often explore underlying mechanisms of biological processes, highlighting the molecular and cellular bases of phenomena such as development, disease, and ecological interactions. - Public Engagement and Education:
The journal also aims to engage the public and scientific community through accessible content that explains research significance and implications for health and the environment.
Trending and Emerging
- Neurobiology and Neuroscience:
There is an increasing emphasis on research exploring neural circuits, synaptic plasticity, and the molecular basis of neurological disorders, reflecting the growing interest in understanding brain function and its implications for mental health. - Microbiome Research:
Research investigating the human microbiome and its role in health, disease, and metabolism is gaining traction, showing the importance of microbial communities in various biological processes. - Cancer Biology and Therapeutics:
A notable increase in studies focusing on cancer mechanisms, therapeutic strategies, and immunotherapies indicates a heightened interest in understanding and combating cancer. - Environmental and Ecological Studies:
Research on the impacts of climate change, biodiversity, and ecosystem health is trending, highlighting the urgency of addressing environmental challenges within biological research. - Gene Editing and Synthetic Biology:
Emerging technologies in gene editing, particularly CRISPR-based approaches, are rapidly advancing, showcasing innovative applications in genetic engineering and synthetic biology.
Declining or Waning
- Traditional Model Organisms:
Research utilizing established model organisms (e.g., mice, fruit flies) may be waning as the field shifts towards more complex systems that better mimic human biology or environmental conditions. - Basic Mechanistic Studies:
There seems to be a decline in purely mechanistic studies that do not have immediate translational applications, as funding and interest increasingly favor research with direct implications for human health and disease. - Single-Discipline Focus:
There is a trend away from research that limits itself to single disciplines, such as basic ecology or traditional microbiology, as interdisciplinary approaches become more favored. - Reductionist Approaches:
Reductionist approaches that focus on isolated biological processes without considering broader ecological or systemic contexts may be losing prominence in favor of integrative and systems biology.
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