HLA

Scope & Guideline

Innovating Immunological Understanding for a Healthier Future

Introduction

Welcome to your portal for understanding HLA, featuring guidelines for its aims and scope. Our guidelines cover trending and emerging topics, identifying the forefront of research. Additionally, we track declining topics, offering insights into areas experiencing reduced scholarly attention. Key highlights include highly cited topics and recently published papers, curated within these guidelines to assist you in navigating influential academic dialogues.
LanguageEnglish
ISSN2059-2302
PublisherWILEY
Support Open AccessNo
CountryUnited Kingdom
TypeJournal
Converge2011, from 2016 to 2024
AbbreviationHLA / HLA
Frequency12 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address111 RIVER ST, HOBOKEN 07030-5774, NJ

Aims and Scopes

The journal 'HLA' focuses on the study of human leukocyte antigens (HLA) and their implications for immunology, transplantation, and disease associations. It serves as a platform for disseminating research that advances the understanding of HLA genetics, molecular biology, and clinical applications.
  1. Characterization of Novel HLA Alleles:
    The journal emphasizes the identification and characterization of new HLA alleles through advanced sequencing techniques, which are crucial for understanding genetic diversity and its implications in transplantation and disease susceptibility.
  2. HLA and Disease Associations:
    Research on the association between specific HLA alleles and various diseases, including autoimmune disorders, infectious diseases, and cancers, is a core focus. This includes studies linking HLA polymorphisms to clinical outcomes and disease severity.
  3. Transplantation Immunology:
    The journal covers topics related to HLA's role in transplantation, particularly in understanding donor-recipient compatibility, the development of donor-specific antibodies, and strategies for improving transplant outcomes.
  4. Molecular and Genetic Techniques:
    A significant portion of the research employs next-generation sequencing and other molecular techniques to explore HLA genetics, focusing on high-resolution typing and the implications of genetic variations.
  5. Immunogenetics and Personalized Medicine:
    The integration of immunogenetics into personalized medicine approaches, particularly in transplantation and autoimmune diseases, is a growing area of interest, reflecting the journal's commitment to translational research.
The journal is experiencing a dynamic evolution in its focus areas, with several emerging themes gaining prominence. These trends reflect advancements in technology and shifts in clinical practice.
  1. Next-Generation Sequencing Applications:
    The use of next-generation sequencing for HLA typing and allele discovery is increasingly prominent, enabling more efficient and accurate identification of alleles and enhancing understanding of genetic diversity.
  2. HLA in COVID-19 Research:
    Research linking HLA alleles to COVID-19 susceptibility and outcomes is rapidly emerging, reflecting the pandemic's impact on immunogenetics and highlighting the relevance of HLA in infectious disease response.
  3. Immunogenetic Factors in Transplant Outcomes:
    There is a growing trend towards researching the impact of specific HLA alleles and haplotypes on transplant outcomes, particularly in relation to donor-specific antibodies and graft-versus-host disease.
  4. Integration of Machine Learning in HLA Studies:
    The application of machine learning techniques in analyzing HLA data for predicting transplant outcomes and understanding immunological responses is emerging as a significant trend, indicating a shift towards data-driven approaches.
  5. Personalized Medicine in Transplantation:
    Increasingly, studies are focusing on personalized medicine approaches in transplantation, including the customization of immunosuppressive therapies based on HLA profiles and patient-specific factors.

Declining or Waning

While the journal has seen significant growth in certain areas, there are themes that appear to be declining in prominence. These waning scopes indicate shifts in research focus or decreased publication activity.
  1. HLA Typing Methodologies:
    Research specifically centered on traditional HLA typing methodologies seems to be declining, as there is a noticeable shift towards next-generation sequencing and more advanced molecular techniques.
  2. HLA Antibody Detection Techniques:
    The exploration of older methodologies for HLA antibody detection, such as complement-dependent cytotoxicity assays, has seen reduced publication frequency as newer, more sensitive techniques gain traction.
  3. General HLA Research without Specific Clinical Application:
    There appears to be a waning interest in purely academic studies of HLA without direct clinical implications, as the focus shifts towards translational research that can impact patient care and treatment outcomes.

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