INTERNATIONAL JOURNAL OF HUMAN GENETICS
Scope & Guideline
Bridging Gaps in Human Genetic Understanding
Introduction
Aims and Scopes
- Clinical Genetics:
Research on the genetic basis of human diseases, including hereditary disorders, cancer genetics, and the implications for genetic counseling. - Molecular Mechanisms of Disease:
Investigation of the molecular pathways and genetic mutations involved in various diseases, including cancer, neurodegenerative disorders, and metabolic syndromes. - Population Genetics and Epidemiology:
Studies focusing on genetic variations across different populations, including genetic epidemiology of diseases and the impact of specific polymorphisms on health outcomes. - Genomic Technologies and Applications:
Utilization of advanced genomic techniques such as CRISPR, next-generation sequencing, and bioinformatics tools to explore genetic variations and their functional consequences. - Translational Research:
Research aimed at translating genetic discoveries into clinical practice, including biomarker discovery, therapeutic targets, and personalized medicine approaches.
Trending and Emerging
- Cancer Genomics:
A significant increase in studies related to the genetic basis of various cancers, including their molecular mechanisms, therapeutic targets, and prognostic markers. - MicroRNA and Long Non-Coding RNA Research:
Growing interest in the role of microRNAs and lncRNAs in gene regulation and their implications in cancer progression and other diseases. - Genetic Counseling and Patient Experience:
A notable trend towards understanding the role of genetic counseling in hereditary diseases, including patient experiences and outcomes related to genetic testing. - Genetic Variations in Complex Diseases:
Increased focus on the association of specific genetic polymorphisms with complex diseases such as diabetes, cardiovascular diseases, and metabolic disorders. - Application of Artificial Intelligence in Genetics:
Emerging research leveraging AI and machine learning techniques for the analysis of genetic data, particularly in cancer diagnostics and image classification.
Declining or Waning
- Environmental Genetics:
Research focusing on the interaction between genetic factors and environmental influences on health has diminished, indicating a possible shift towards more molecular and clinical aspects. - Traditional Genetic Mapping Studies:
The use of classical genetic mapping techniques, such as linkage analysis, seems to be less prevalent, possibly due to the rise of high-throughput genomic approaches. - Basic Genetic Studies Without Clinical Relevance:
Publications that focus purely on basic genetic mechanisms without direct clinical implications may be decreasing, reflecting a trend towards more applied and translational research.
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