Immunity
Scope & Guideline
Pioneering research in immunity and infectious diseases.
Introduction
Aims and Scopes
- Autoimmunity and Immune Mediated Diseases:
Research articles frequently investigate the pathogenesis of autoimmune diseases, including systemic lupus erythematosus, rheumatoid arthritis, and others, exploring underlying mechanisms and potential therapeutic targets. - Animal Models in Immunology:
The journal publishes studies utilizing animal models to simulate human autoimmune conditions, providing insights into disease mechanisms and testing new treatments. - Molecular Mechanisms of Immunity:
A key focus is on the molecular and cellular mechanisms underlying immune responses, including the role of various cytokines, immune cells, and signaling pathways. - Innovative Therapeutic Approaches:
The journal highlights novel therapeutic strategies for modulating immune responses, including the use of small molecules, biologics, and gene therapies. - Bioinformatics and Systems Biology:
Research utilizing bioinformatics approaches to analyze immune-related data and identify new biomarkers or therapeutic targets is a significant component of the journal.
Trending and Emerging
- MicroRNA and Circular RNA in Autoimmunity:
There is a growing interest in the roles of microRNAs and circular RNAs in modulating immune responses and their implications in autoimmune diseases, indicating a shift towards understanding post-transcriptional regulation. - Gut Microbiota and Immune Modulation:
Research exploring the relationship between gut microbiota and immune system function is gaining traction, highlighting the importance of the microbiome in autoimmune disease pathogenesis. - Inflammation and Metabolic Pathways:
Emerging studies focus on the intersection between inflammation and metabolic pathways, particularly how metabolic dysregulation can influence immune responses and contribute to autoimmune disorders. - Regulatory Mechanisms in Immune Tolerance:
There is an increasing emphasis on understanding the mechanisms that govern immune tolerance, particularly in the context of autoimmunity and transplantation. - Therapeutic Targeting of Autophagy:
The potential of autophagy modulation as a therapeutic strategy in autoimmune diseases is becoming a prominent theme, reflecting a broader interest in cellular homeostasis and immune regulation.
Declining or Waning
- Traditional Cytokine Research:
Studies focusing solely on individual cytokines without integrating broader immune network analyses or novel therapeutic perspectives appear to be less frequent, as the field moves towards more complex interactions and pathways. - Basic Immunology without Clinical Relevance:
Research that lacks a direct connection to clinical applications or patient outcomes is becoming less common, with a stronger emphasis now placed on translational research. - Epidemiological Studies on Autoimmune Diseases:
There has been a noticeable decrease in articles focusing solely on the epidemiology of autoimmune diseases, as the field shifts towards understanding mechanisms and treatment options.
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