INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
Scope & Guideline
Pioneering Research in Cancer Treatment and Biology.
Introduction
Aims and Scopes
- Clinical Outcomes in Radiation Therapy:
Research examining the efficacy and safety of various radiation therapy modalities, including comparisons of treatment techniques, dosimetric analyses, and long-term patient outcomes. - Radiobiology and Mechanisms of Action:
Studies investigating the cellular and molecular mechanisms underlying radiation effects on cancer cells, including radiosensitivity, tumor microenvironment interactions, and immune responses. - Technological Advances in Radiation Treatment:
Innovations in radiation therapy technologies, such as intensity-modulated radiation therapy (IMRT), proton therapy, and stereotactic body radiation therapy (SBRT), and their implementation in clinical practice. - Quality Assurance and Treatment Planning:
Research focused on improving treatment planning processes, quality assurance measures, and the use of artificial intelligence in enhancing the accuracy and efficiency of radiation therapy. - Healthcare Disparities and Access to Care:
Investigations into disparities in treatment access and outcomes among diverse patient populations, with a focus on improving equity in radiation oncology. - Patient-Centered Care and Quality of Life:
Research examining the impact of radiation therapy on patients' quality of life, including symptom management, psychosocial factors, and patient-reported outcomes.
Trending and Emerging
- Artificial Intelligence and Machine Learning:
The integration of AI and machine learning in radiation oncology is increasingly prevalent, focusing on automating treatment planning, improving segmentation accuracy, and predicting treatment outcomes. - Personalized Radiation Therapy:
There is a growing emphasis on tailoring radiation therapy based on individual patient characteristics, including genomic profiles, tumor biology, and treatment response, to optimize outcomes. - Immunotherapy Combinations:
Research exploring the synergistic effects of combining radiation therapy with immunotherapy is trending, as this approach aims to enhance antitumor responses and improve patient prognosis. - Health Equity and Access to Care:
An increasing focus on addressing disparities in access to radiation therapy and understanding the social determinants of health affecting treatment outcomes for underrepresented populations. - Quality of Life and Patient-Reported Outcomes:
Emerging studies are prioritizing the assessment of quality of life and patient-reported outcomes following radiation therapy, highlighting the importance of holistic patient care.
Declining or Waning
- Traditional Radiation Techniques:
Research on conventional radiation therapy techniques has decreased as interest shifts toward innovative methods such as proton therapy and SBRT, which offer improved outcomes and reduced side effects. - Basic Radiobiology Studies:
There has been a noticeable decline in basic radiobiology studies focusing solely on cellular responses to radiation, as the field increasingly emphasizes clinical applications and translational research. - Single-Institution Studies:
The prevalence of single-institution studies has waned in favor of multi-institutional collaborations and large-scale trials, which provide more generalizable and robust data.
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