JOURNAL OF ANALYTICAL TOXICOLOGY
Scope & Guideline
Leading the Charge in Toxic Substance Detection
Introduction
Aims and Scopes
- Analytical Method Development:
The journal emphasizes the development and validation of new analytical methods for the detection and quantification of drugs, metabolites, and toxic substances in various biological matrices. - Forensic Toxicology Studies:
A significant focus is placed on forensic applications, including case studies that explore the toxicological profiles of substances involved in fatalities and legal cases. - Emerging Psychoactive Substances:
Research often highlights the identification and characterization of novel psychoactive substances (NPS), reflecting the ongoing evolution of drug use patterns and associated health risks. - Biomarkers of Exposure:
The journal covers the exploration of biomarkers for drug exposure, including studies on how substances are metabolized and their implications for toxicological assessments. - Public Health and Safety Implications:
Research published in the journal often addresses public health concerns related to drug use, impaired driving, overdose incidents, and the implications for law enforcement and healthcare.
Trending and Emerging
- Synthetic Cannabinoids and Designer Drugs:
There is a marked increase in studies focusing on synthetic cannabinoids and designer benzodiazepines, highlighting their rising prevalence and the need for improved detection methods. - Postmortem Toxicology Investigations:
An increasing number of publications are dedicated to postmortem toxicology, emphasizing the analysis of drug concentrations and metabolites in cases of suspected overdose or intoxication. - Drug Impairment and Driving Under Influence (DUID):
Research related to drug impairment in driving contexts is gaining traction, with studies examining the relationship between drug concentrations and impairment effects. - Methodological Innovations:
Emerging themes include the development of novel extraction and analytical techniques, such as microextraction methods and high-throughput screening, to improve the efficiency and sensitivity of toxicological analyses. - Cross-Reactivity and Immunoassay Challenges:
An increased focus on the challenges posed by cross-reactivity in immunoassays for drug detection reflects the need for more accurate and reliable testing methods.
Declining or Waning
- Traditional Drug Testing Techniques:
As analytical techniques evolve, there is a noticeable decline in studies focused on conventional drug testing methods, with a shift toward more advanced methodologies such as LC-MS-MS and high-resolution mass spectrometry. - General Toxicology Reviews:
There appears to be a decrease in the publication of broad review articles on general toxicology, as the journal increasingly focuses on specific case studies and methodological advancements. - Focus on Older Substance Classes:
Research on older classes of substances, such as classic benzodiazepines, is becoming less frequent, possibly due to the increasing prevalence of novel and designer drugs.
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