JOURNAL OF TOXICOLOGICAL SCIENCES

Scope & Guideline

Advancing the Frontiers of Toxicology

Introduction

Immerse yourself in the scholarly insights of JOURNAL OF TOXICOLOGICAL SCIENCES with our comprehensive guidelines detailing its aims and scope. This page is your resource for understanding the journal's thematic priorities. Stay abreast of trending topics currently drawing significant attention and explore declining topics for a full picture of evolving interests. Our selection of highly cited topics and recent high-impact papers is curated within these guidelines to enhance your research impact.
LanguageEnglish
ISSN0388-1350
PublisherJAPANESE SOC TOXICOLOGICAL SCIENCES
Support Open AccessNo
CountryJapan
TypeJournal
Convergefrom 1976 to 2024
AbbreviationJ TOXICOL SCI / J. Toxicol. Sci.
Frequency4 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
AddressINTERNATIONAL MEDICAL INFORMATION CENTER, SHINANOMACHI RENGAKAN, 35 SHINANO-MACHI, SHINJUKU-KU, TOKYO 160-0016, JAPAN

Aims and Scopes

The Journal of Toxicological Sciences focuses on the investigation of toxic substances and their effects on biological systems, with an emphasis on understanding mechanisms of toxicity, risk assessment, and the development of innovative methodologies for toxicity testing.
  1. Mechanistic Toxicology:
    The journal emphasizes studies that elucidate the mechanisms by which toxic substances cause adverse effects at the cellular and molecular levels.
  2. Risk Assessment and Safety Evaluation:
    Research articles often focus on the development of methodologies for assessing the risks associated with exposure to various chemicals, including pharmaceuticals and environmental toxins.
  3. Innovative Testing Methods:
    The journal promotes the advancement of new experimental models and in vitro systems for toxicity testing, reflecting a commitment to improving predictive accuracy for human health impacts.
  4. Comparative Toxicology:
    Studies comparing the toxicological responses across different species, including humans, are a core focus, providing insights into species-specific susceptibility and relevance.
  5. Environmental and Occupational Toxicology:
    Research on the toxic effects of environmental pollutants and occupational exposures is prevalent, addressing public health concerns and regulatory implications.
  6. Biomarkers of Toxicity:
    Investigations into biomarkers that can indicate exposure to or effects from toxic substances are frequently published, aiding in early detection and intervention strategies.
Recent publications in the Journal of Toxicological Sciences reflect emerging themes that are gaining traction, highlighting the evolving landscape of toxicological research and its applications.
  1. Microbiome and Toxicology:
    There is an increasing focus on the interactions between toxic substances and the gut microbiome, exploring how these relationships influence toxicity and health outcomes.
  2. Machine Learning and Computational Toxicology:
    The integration of machine learning and artificial intelligence in predicting toxicity and drug safety is a rapidly growing area, demonstrating the journal's responsiveness to technological advancements.
  3. Neurotoxicity Assessment:
    Research on neurotoxicity, including studies on neuroprotective mechanisms and the impacts of environmental toxins on neurological health, is emerging as a significant theme.
  4. Environmental Exposures and Health Effects:
    There is a heightened emphasis on the health effects of environmental exposures, particularly in the context of climate change and pollution, aligning with global public health priorities.
  5. Epigenetic Mechanisms of Toxicity:
    Studies investigating the role of epigenetics in mediating toxic effects are on the rise, reflecting a deeper understanding of how environmental factors can influence gene expression and disease.

Declining or Waning

While the journal continues to cover a wide array of toxicological topics, certain themes have seen reduced emphasis in recent publications, indicating a shift in research focus and priorities within the field.
  1. Traditional Animal Testing Models:
    There is a noticeable decline in studies relying solely on traditional animal models for toxicity assessment, reflecting a broader shift towards alternative methods, such as in vitro and computational models.
  2. Single Chemical Exposure Studies:
    Research focusing on the toxicity of single chemicals in isolation has become less prominent, as there is a growing recognition of the need to study mixtures and real-world exposure scenarios.
  3. Acute Toxicity Studies:
    The publication of studies solely investigating acute toxicity has decreased, with more emphasis being placed on chronic effects and long-term health outcomes from exposure.
  4. Cytotoxicity without Mechanistic Insight:
    There are fewer publications focusing on cytotoxicity data alone without accompanying mechanistic investigations, indicating a trend towards more holistic approaches in toxicology research.

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