JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
Scope & Guideline
Advancing the Frontiers of Steroid Science
Introduction
Aims and Scopes
- Steroid Biochemistry and Metabolism:
Research in this area involves the study of biochemical pathways related to steroid hormones, including their synthesis, metabolism, and the role of enzymes such as cytochrome P450 in steroidogenesis. - Hormonal Regulation and Disease:
This scope focuses on the impact of steroid hormones in various diseases, particularly cancers (e.g., breast and prostate cancer), metabolic disorders, and reproductive health issues. - Analytical Techniques in Steroid Research:
The journal emphasizes advancements in analytical techniques such as liquid chromatography-mass spectrometry (LC-MS/MS), which are crucial for quantifying steroid hormones and their metabolites in biological samples. - Endocrine Disruption and Environmental Factors:
Research addressing the effects of environmental chemicals and endocrine disruptors on steroid hormone function and metabolism is a key area of interest, particularly in relation to reproductive health. - Neurosteroids and Cognitive Functions:
Studies on the role of neuroactive steroids in the central nervous system and their implications for neuropsychiatric disorders and cognitive function are increasingly featured. - Clinical Applications and Therapeutics:
The journal explores the therapeutic potential of steroid hormones and their analogs in various clinical contexts, including hormone replacement therapies and cancer treatments.
Trending and Emerging
- Vitamin D and Its Metabolites:
Research on vitamin D, its metabolites, and their diverse roles in health, including immune function and disease prevention, has gained considerable attention, reflecting a broader interest in the implications of vitamin D deficiency. - Steroid Hormones in Cancer Therapy:
An increasing number of studies are exploring the role of steroid hormones in cancer treatment, particularly the development of novel therapeutic agents targeting steroid receptors in hormone-dependent tumors. - Neuroactive Steroids and Mental Health:
There is a growing focus on neuroactive steroids and their impact on mental health conditions, indicating an emerging interest in the links between steroid hormones and neuropsychiatric disorders. - Metabolomics and Personalized Medicine:
The application of metabolomics to understand individual variations in steroid metabolism and its implications for personalized medicine is a rapidly expanding area of research. - Endocrine Disruption and Public Health:
Research addressing the effects of endocrine disruptors on human health, particularly in relation to reproductive and metabolic disorders, has gained momentum, highlighting the intersection of environmental science and steroid biochemistry.
Declining or Waning
- Basic Steroid Biochemistry:
There has been a noticeable decrease in publications focusing solely on the fundamental aspects of steroid biochemistry without clinical or applied context, possibly due to the increasing complexity and translational nature of steroid research. - Historical Perspectives on Steroids:
Papers reflecting on historical developments in steroid research or retrospective analyses have become less frequent, as the focus shifts towards contemporary issues and innovative methodologies. - Plant Steroids and Phytochemistry:
Research on plant-derived steroids and their potential applications has waned, as more attention is directed towards synthetic and semi-synthetic steroid compounds with targeted therapeutic effects. - Animal Models in Steroid Research:
There seems to be a reduced emphasis on studies utilizing traditional animal models for steroid research, potentially due to the rise of in vitro and computational models that offer more direct insights into human physiology.
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