MECHANISMS OF AGEING AND DEVELOPMENT
Scope & Guideline
Illuminating Mechanisms That Shape Our Lives
Introduction
Aims and Scopes
- Cellular Senescence and Aging Mechanisms:
The journal extensively covers research on cellular senescence, its role in aging, and its implications for age-related diseases. It investigates the molecular pathways involved in senescence, including the senescence-associated secretory phenotype (SASP), and how these processes affect tissue function and regeneration. - Biomarkers of Aging:
A core area of focus is the identification and validation of biomarkers associated with aging and age-related diseases. This includes the exploration of genetic, epigenetic, and metabolic markers that can predict biological age and health outcomes. - Therapeutic Interventions:
Research on therapeutic strategies to mitigate aging effects, including pharmacological agents (like senolytics and geroprotectors), dietary restrictions, and lifestyle interventions, is a significant aspect of the journal's scope. These studies aim to translate basic research into clinical applications. - Age-Related Diseases:
The journal addresses various diseases associated with aging, such as neurodegenerative disorders, cardiovascular diseases, and metabolic syndromes. It emphasizes understanding the pathophysiology of these conditions and their interrelations with aging processes. - Interdisciplinary Research:
The journal promotes interdisciplinary studies that integrate insights from genetics, molecular biology, biochemistry, and clinical research to provide a comprehensive understanding of aging and its impact on health.
Trending and Emerging
- Senolytics and Senotherapeutics:
There is a notable increase in research focused on senolytic drugs and therapies aimed at selectively eliminating senescent cells to improve healthspan. This trend underscores the potential therapeutic strategies to combat aging-related diseases. - Inflammaging and Immune Response:
Emerging studies are increasingly exploring the concept of 'inflammaging', the chronic low-grade inflammation associated with aging, and its role in various diseases. This theme is critical for understanding the intersection of aging and the immune system. - Microbiome and Aging Interactions:
Research is trending towards understanding how gut microbiota influence aging processes and age-related diseases. The gut-brain axis and its implications for cognitive decline and metabolic health are gaining significant attention. - Personalized Aging Interventions:
There is a growing focus on personalized approaches to aging interventions, including tailored dietary and pharmacological strategies based on individual genetic and metabolic profiles. This trend aligns with advancements in precision medicine. - Interdisciplinary Approaches:
An increasing number of studies are utilizing interdisciplinary methodologies, combining insights from genetics, epigenetics, and systems biology to create a more holistic understanding of aging and its associated diseases.
Declining or Waning
- Basic Mechanistic Studies in Non-Mammalian Models:
Research utilizing non-mammalian models (like yeast and nematodes) for basic mechanistic studies of aging has seen a decrease. While these models provided valuable insights, there is now a stronger emphasis on mammalian systems that are more directly translatable to human health. - Traditional Models of Aging:
There has been a waning interest in traditional aging models that do not incorporate modern techniques such as genomics and proteomics. Studies that rely solely on classical methods without integrating advanced technologies are less frequent. - Focus on Single Biomarkers:
Research focusing on single biomarkers of aging is diminishing in favor of more comprehensive biomarker panels and systems biology approaches. The complexity of aging necessitates a broader perspective that considers multiple interacting factors. - Aging and Gender Studies:
Although still relevant, studies specifically addressing gender differences in aging are less frequent compared to the increasing emphasis on gender-neutral approaches that consider a wide range of biological and environmental factors.
Similar Journals
EXPERIMENTAL GERONTOLOGY
Advancing the Science of Aging for a Healthier TomorrowEXPERIMENTAL GERONTOLOGY is a prestigious journal published by PERGAMON-ELSEVIER SCIENCE LTD, dedicated to the evolving field of aging research. With a rich history dating back to 1964 and continuing through 2024, this journal aims to advance the understanding of the biological processes underlying aging and develop interdisciplinary approaches to improve healthspan. ENCOMPASSING a broad scope, including *biochemistry*, *cell biology*, *endocrinology*, *genetics*, and *molecular biology*, it holds impressive rankings in the 2023 Scopus Ranks, featuring in Q1 and Q2 quartiles across multiple categories. This positions it as a vital resource for researchers and professionals focused on gerontology and related fields. As a subscription-based journal without open access, EXPERIMENTAL GERONTOLOGY ensures the dissemination of high-quality research through rigorous peer review, making it an essential publication for those aspiring to remain at the forefront of aging studies.
REJUVENATION RESEARCH
Unlocking the Secrets of Lifelong VitalityRejuvenation Research is a premier journal dedicated to the advancing field of gerontology and aging research, published by Mary Ann Liebert, Inc. Established in 2000, the journal serves as a pivotal platform for the dissemination of scholarly articles that explore the complex mechanisms of aging and innovative approaches to rejuvenation. With an impact factor reflective of its robust scholarly contributions, the journal currently holds a Q4 ranking in Aging and a Q3 ranking in Geriatrics and Gerontology, showcasing its relevance in the academic community. This periodic publication, welcoming open access submissions, invites researchers, professionals, and students alike to engage with cutting-edge findings that could shape future geriatric practices and enhance quality of life. The journal underscores the importance of interdisciplinary collaboration, encouraging explorations that intersect with biochemistry, genetics, and other vital areas of study. Through its ongoing commitment to high-quality research, Rejuvenation Research remains a critical resource for understanding the biological underpinnings of aging and the strategies to mitigate its effects.
Physiology and Pharmacology
Fostering collaboration in the realms of physiology and pharmacology.Physiology and Pharmacology is a distinguished open access journal that has been disseminating high-quality research in the fields of physiology and pharmacology since its inception in 1997. Published by the Iranian Society of Physiology & Pharmacology, this journal offers a platform for scholars and practitioners to share innovative findings and advancements that contribute to the understanding of biological systems and drug action. With its ISSN 2476-5236 and E-ISSN 2476-5244, it ensures global reach and accessibility. The journal is positioned in the third quartile for Linguistics and Language and fourth quartile in both Pharmacology and Physiology categories according to Scopus rankings, reflecting a commitment to expanding knowledge within these interdisciplinary domains. Set within the academic landscape of Iran, the journal aims to bridge regional research with the international community, providing valuable insights into physiological processes and pharmacological developments. In light of its open access model, the Physiology and Pharmacology journal plays a crucial role in enhancing the visibility of research outcomes and fostering collaboration among researchers, professionals, and students on a global scale.
Neuropeptides
Advancing Knowledge in Neuroscience and EndocrinologyNeuropeptides is a prestigious, peer-reviewed journal published by Elsevier, focusing on the critical role of neuropeptides in various biological processes and their implications in cellular and molecular neuroscience, endocrinology, and neurology. With an impact factor reflecting its influence in the field and a diverse audience ranging from researchers to healthcare professionals, the journal serves as an essential platform for the dissemination of groundbreaking research from 1980 to 2024. Adhering to high academic standards, Neuropeptides holds a Q3 ranking in Cellular and Molecular Neuroscience and Endocrine and Autonomic Systems, alongside a solid Q2 ranking in both Endocrinology and Neurology. This positions the journal at the forefront of its disciplines, contributing valuable insights into the understanding of neuropeptide functions in health and disease. By not operating as an Open Access journal, it ensures sustainability in the publishing process while upholding rigorous review standards. Researchers, professionals, and students are encouraged to engage with the findings published in this journal, which plays a vital role in advancing knowledge and fostering collaboration within the neuroscientific community.
npj Aging
Advancing knowledge on the complexities of aging.npj Aging, published by Nature Publishing Group, is a pioneering journal dedicated to advancing our understanding of the biological, clinical, and social aspects of aging. With an E-ISSN of 2731-6068, this open-access journal aims to foster innovative research and interdisciplinary dialogue among scientists, clinicians, and policy-makers. As of its inception in 2023, the journal has quickly established itself within the scholarly community, ranking 15th in Medicine (Geriatrics and Gerontology) and 12th in Biochemistry, Genetics, and Molecular Biology focusing on Aging, reflecting a strong percentile standing in both categories. The journal provides a platform for disseminating important findings that address the complexities of aging, ensuring accessibility for a broader audience. Located at the Macmillan Building, 4 Crinan St, London, England, npj Aging aspires to be an essential resource for those seeking to enhance their understanding and contribute to the field of gerontology.
FREE RADICAL BIOLOGY AND MEDICINE
Exploring the Dynamics of Free Radicals in Health and DiseaseFREE RADICAL BIOLOGY AND MEDICINE, published by Elsevier Science Inc, is a premier journal dedicated to the field of biochemistry and medical physiology. With an ISSN of 0891-5849 and an E-ISSN of 1873-4596, this journal stands out with its impressive ranking in the 2023 category quartiles: Q1 in Biochemistry and Q1 in Physiology (medical). Specifically, it has achieved a remarkable position of 29th out of 438 in Biochemistry and 8th out of 113 in Physiology, placing it firmly in the 93rd percentile of its field, as per Scopus rankings. Since its inception in 1987, the journal has focused on advancing the understanding of free radicals and their role in biological processes, encompassing a wide range of topics from oxidative stress to therapeutic applications. Although it does not currently offer open access, the journal's rigorous peer-review process and impactful research ensure that it remains a valuable resource for researchers and professionals seeking to explore the intricate relationships between free radicals and health. The journal's headquarters are located at STE 800, 230 Park Ave, New York, NY 10169, reflecting its esteemed place within the scientific community and commitment to high-quality research.
Immunity & Ageing
Innovating Understanding of Aging Through Immune PerspectivesImmunity & Ageing is a distinguished open access journal published by BMC, committed to advancing the understanding of the interplay between immunological processes and aging. Since its inception in 2004, this journal has established itself as a leading platform for disseminating quality research, evidenced by its Q1 rankings in both Aging and Immunology categories for 2023. With an impressive Scopus ranking that places it in the top percentile of related fields, it serves as an essential resource for researchers, professionals, and students eager to explore the nuances of immune aging and age-related diseases. The journal's open access policy ensures wide accessibility and visibility, promoting collaborative discourse and innovation across the global scientific community. Based in the United Kingdom, Immunity & Ageing is set to continue its significant contribution to the field, inviting submissions that push the boundaries of knowledge and application in immunology and gerontology.
Journal of Biochemistry
Your essential resource for biochemical advancements.Journal of Biochemistry, published by Oxford University Press, is a prestigious academic journal that has been at the forefront of biochemical research since its inception in 1922. With an ISSN of 0021-924X and an E-ISSN of 1756-2651, this journal serves as a platform for disseminating high-quality research in the fields of biochemistry, molecular biology, and medicine, holding impressive rankings such as Q2 in Biochemistry and Medicine (miscellaneous) in 2023. As of 2024, the journal continues to explore significant topics in these areas, offering valuable insights for researchers, professionals, and students alike. The journal does not currently offer open access, but it remains a vital resource for anyone in the biochemical community seeking to stay updated on the latest discoveries and advancements. With its rich history and dedication to scientific excellence, the Journal of Biochemistry is an indispensable part of the scholarly landscape.
MOLECULAR ASPECTS OF MEDICINE
Decoding the Molecular Mechanisms of DiseaseMOLECULAR ASPECTS OF MEDICINE is a premier journal published by Elsevier, focusing on groundbreaking research in the fields of biochemistry, molecular biology, and medicine. With an impressive impact factor and ranking within the top quartile across multiple categories, including Q1 in Biochemistry, Clinical Biochemistry, and Molecular Medicine, it serves as an essential platform for sharing innovative findings that advance our understanding of molecular mechanisms in health and disease. The journal, which has been in publication since 1976, provides a diverse range of articles, addressing both fundamental and applied aspects of molecular medicine, thus appealing to a broad audience of researchers, professionals, and students. While MOLECULAR ASPECTS OF MEDICINE does not currently offer Open Access options, it remains a vital resource for accessing high-quality, peer-reviewed scholarly works that significantly contribute to the advancement of biomedical research.
Advances in Gerontology
Connecting Scholars to the Science of AgingAdvances in Gerontology is a pivotal academic journal dedicated to the field of gerontology, published by PLEIADES PUBLISHING INC. With its ISSN 2079-0570 and E-ISSN 2079-0589, this journal serves as an essential platform for researchers, healthcare professionals, and students focused on aging and related health issues. Although currently not an open-access journal, it aspires to enrich the scholarly community by disseminating high-quality research from 2011 through 2024. The journal is recognized in the lower quartile of its category, ranking Q4 in both Geriatrics and Gerontology, reflecting its commitment to addressing emerging topics in the aging population despite its lower visibility in the competitive landscape. As it continues to explore critical areas in gerontology, Advances in Gerontology invites contributions that advance knowledge, foster understanding, and inform practices within this essential field of study.