CELL

Scope & Guideline

Transforming the landscape of biochemistry and molecular biology.

Introduction

Explore the comprehensive scope of CELL through our detailed guidelines, including its aims and scope. Stay updated with trending and emerging topics, and delve into declining areas to understand shifts in academic interest. Our guidelines also showcase highly cited topics, featuring influential research making a significant impact. Additionally, discover the latest published papers and those with high citation counts, offering a snapshot of current scholarly conversations. Use these guidelines to explore CELL in depth and align your research initiatives with current academic trends.
LanguageEnglish
ISSN0092-8674
PublisherCELL PRESS
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 1974 to 2024
AbbreviationCELL / Cell
Frequency26 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address50 HAMPSHIRE ST, FLOOR 5, CAMBRIDGE, MA 02139

Aims and Scopes

The journal 'CELL' focuses on advancing the understanding of cellular mechanisms, particularly in the context of aging and associated diseases. It encompasses a wide range of topics that explore the molecular and physiological underpinnings of cellular behavior, emphasizing translational research aimed at improving healthspan and lifespan.
  1. Cellular Aging Mechanisms:
    Research on the biological processes that contribute to aging at the cellular level, including cellular senescence, epigenetic changes, and oxidative stress.
  2. Neurodegenerative Diseases:
    Investigation into the cellular and molecular mechanisms underlying neurodegenerative diseases such as Alzheimer's and Parkinson's, focusing on tau pathology, amyloid-beta dynamics, and neuroinflammation.
  3. Metabolism and Aging:
    Studies examining how metabolic pathways and interventions, such as caloric restriction and pharmacological agents, influence aging processes and health outcomes.
  4. Stem Cell Biology:
    Exploration of stem cell behavior in aging, including their differentiation potential, regenerative capacity, and response to environmental cues.
  5. Microbiome and Aging:
    Research on the interplay between the gut microbiome and aging, investigating how microbial communities affect metabolic health and age-related diseases.
  6. Therapeutic Interventions:
    Development and evaluation of therapeutic strategies, including senolytics and dietary interventions, aimed at mitigating the effects of aging and enhancing healthspan.
  7. Systems Biology Approaches:
    Utilization of multi-omics strategies to understand the complex interactions governing cellular aging and disease.
The journal 'CELL' has identified several emerging themes that highlight the evolving landscape of aging research. These trends reflect the increasing complexity of biological systems and the need for interdisciplinary approaches.
  1. Epigenetic Modifications and Aging:
    A growing body of research is focusing on how epigenetic changes influence aging processes, including DNA methylation and histone modifications, as potential biomarkers and therapeutic targets.
  2. Inflammaging and Immune Senescence:
    Increasing attention is being paid to the role of chronic inflammation in aging and how immune system alterations contribute to age-related diseases, emphasizing the need for immunomodulatory therapies.
  3. Microbiome Influence on Aging:
    Emerging studies are exploring the role of the gut microbiome in modulating aging and healthspan, highlighting the potential for microbiome-targeted interventions.
  4. Technological Advances in Aging Research:
    The integration of advanced technologies such as single-cell sequencing and multi-omics approaches is rapidly gaining traction, enabling more nuanced insights into aging mechanisms.
  5. Personalized Medicine and Aging:
    There is a trend towards developing personalized therapeutic strategies based on individual genetic and metabolic profiles, aiming to optimize interventions for age-related conditions.
  6. Regenerative Medicine and Tissue Engineering:
    Research focusing on harnessing the potential of stem cells and regenerative medicine to combat age-related degeneration is on the rise, with implications for tissue engineering and repair.

Declining or Waning

While 'CELL' continues to explore various themes, certain topics have seen a decline in prominence over recent years, reflecting shifts in research focus and priorities.
  1. Traditional Pharmacological Interventions:
    There has been a noticeable decrease in studies focusing solely on traditional small-molecule pharmacological interventions, with a shift towards exploring holistic and multi-targeted therapeutic strategies.
  2. Basic Cellular Mechanisms without Disease Context:
    Research that purely investigates cellular mechanisms in isolation, without a clear connection to aging or disease relevance, is becoming less frequent as the journal emphasizes translational and applied research.
  3. Animal Models with Limited Relevance to Human Aging:
    Studies using outdated or less relevant animal models for aging research are declining as the field moves towards models that better mimic human aging processes.
  4. Single-Factor Studies:
    There is a waning interest in research that examines the effects of single factors on aging, as the complexity of aging necessitates a more integrative approach.

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