METABOLIC BRAIN DISEASE
Scope & Guideline
Elevating research on brain health and metabolism.
Introduction
Aims and Scopes
- Metabolic Dysfunction and Neurological Disorders:
The journal emphasizes research on how metabolic disorders, such as diabetes and obesity, contribute to the pathogenesis of various neurological diseases, including Alzheimer's, Parkinson's, and multiple sclerosis. - Neuroinflammation and Oxidative Stress:
It explores the role of neuroinflammation and oxidative stress in brain disorders, focusing on their contributions to neuronal damage and cognitive decline. - Therapeutic Approaches and Drug Development:
Research on novel pharmacological and non-pharmacological interventions, including natural compounds and lifestyle modifications, aimed at mitigating metabolic and neurological disorders is a core focus. - Molecular and Genetic Mechanisms:
The journal publishes studies that investigate the molecular and genetic underpinnings of brain diseases, including the role of non-coding RNAs and metabolic enzymes. - Animal Models and Clinical Studies:
Utilizing both experimental animal models and clinical studies, the journal aims to bridge the gap between laboratory research and therapeutic applications in humans.
Trending and Emerging
- Gut-Brain Axis Research:
An increasing number of studies are investigating the gut-brain connection, particularly how gut microbiota and metabolites influence neurological disorders and cognitive functions. - Network Pharmacology and Integrative Approaches:
The use of network pharmacology and integrative approaches to drug discovery is on the rise, reflecting a shift towards understanding the multi-target effects of therapies rather than focusing on single molecules. - Neuroprotective Natural Compounds:
There is a growing interest in the neuroprotective properties of natural compounds, with many studies exploring how dietary components and herbal extracts can prevent or mitigate brain disorders. - MicroRNA and Epigenetics:
Research focusing on the role of microRNAs and epigenetic modifications in metabolic and neurological diseases is trending, emphasizing their potential as biomarkers and therapeutic targets. - Exercise and Lifestyle Interventions:
An emerging focus on the effects of physical activity and lifestyle changes on brain health is evident, with studies documenting how exercise can influence cognitive function and metabolic health.
Declining or Waning
- Traditional Drug Development Approaches:
There is a noticeable decrease in publications focusing solely on conventional pharmacological approaches, as research shifts towards integrative and holistic treatment strategies. - Basic Neuroanatomy Studies:
Research that primarily focuses on basic neuroanatomical studies without linking to metabolic or pathological conditions has become less prominent, indicating a shift towards more clinically relevant investigations. - Single-Factor Studies:
Studies examining single metabolic factors in isolation are declining, as there is a growing preference for comprehensive, multi-factorial approaches that consider the interplay of various metabolic and neurological factors.
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