MOLECULAR CARCINOGENESIS

Scope & Guideline

Illuminating the Science Behind Cancer Progression

Introduction

Welcome to your portal for understanding MOLECULAR CARCINOGENESIS, featuring guidelines for its aims and scope. Our guidelines cover trending and emerging topics, identifying the forefront of research. Additionally, we track declining topics, offering insights into areas experiencing reduced scholarly attention. Key highlights include highly cited topics and recently published papers, curated within these guidelines to assist you in navigating influential academic dialogues.
LanguageEnglish
ISSN0899-1987
PublisherWILEY
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 1988 to 2024
AbbreviationMOL CARCINOGEN / Mol. Carcinog.
Frequency12 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address111 RIVER ST, HOBOKEN 07030-5774, NJ

Aims and Scopes

The journal 'Molecular Carcinogenesis' focuses on the molecular mechanisms underlying cancer development, progression, and treatment. It emphasizes studies that explore the genetic, epigenetic, and environmental factors contributing to carcinogenesis. The journal publishes original research, reviews, and case studies that provide insights into the molecular pathways involved in cancer, aiming to bridge the gap between basic research and clinical applications.
  1. Molecular Mechanisms of Carcinogenesis:
    The journal primarily investigates the molecular and cellular mechanisms that lead to cancer, including genetic mutations, epigenetic modifications, and signaling pathways.
  2. Cancer Biology and Tumor Microenvironment:
    Research on how tumors interact with their microenvironment, including the role of stromal cells, immune cells, and extracellular matrix components in tumor progression and metastasis.
  3. Therapeutic Targets and Drug Resistance:
    Exploration of novel therapeutic targets, mechanisms of drug resistance, and the development of innovative treatment strategies, particularly in the context of targeted and immunotherapy.
  4. Biomarkers for Cancer Diagnosis and Prognosis:
    Studies aimed at identifying and validating biomarkers that can improve cancer diagnosis, prognosis, and treatment response.
  5. Translational Research:
    Research that translates laboratory findings into clinical applications, focusing on how molecular insights can inform cancer prevention, diagnosis, and treatment.
Recent trends in 'Molecular Carcinogenesis' indicate a shift towards several emerging themes that reflect the evolving landscape of cancer research. These themes highlight the increasing complexity of cancer biology and the need for innovative approaches to treatment and understanding disease mechanisms.
  1. Targeting the Tumor Microenvironment:
    A growing body of research is focusing on the tumor microenvironment, including the roles of cancer-associated fibroblasts, immune cells, and extracellular vesicles in tumor progression and therapy response.
  2. Molecular Mechanisms of Drug Resistance:
    There is an increasing emphasis on understanding the molecular mechanisms underlying drug resistance, particularly in the context of targeted therapies and immunotherapy.
  3. Epigenetic Modifications in Cancer:
    Research into the role of epigenetic changes, such as DNA methylation and histone modifications, in cancer initiation and progression is gaining momentum, reflecting a deeper understanding of gene regulation.
  4. Precision Medicine and Personalized Therapy:
    Emerging studies are focusing on precision medicine approaches that tailor treatments based on individual genetic profiles and tumor characteristics, enhancing therapeutic efficacy.
  5. Non-coding RNAs and Their Roles in Cancer:
    The role of non-coding RNAs, including long non-coding RNAs and microRNAs, in regulating cancer pathways and their potential as therapeutic targets is increasingly prominent.

Declining or Waning

While 'Molecular Carcinogenesis' has consistently focused on various aspects of cancer biology, certain themes appear to be declining in prominence based on recent publications. These waning scopes may reflect shifts in research priorities or advancements in understanding that have moved the field in new directions.
  1. Traditional Chemotherapy Studies:
    There is a noticeable decrease in publications focusing solely on traditional chemotherapy mechanisms and outcomes, as research increasingly emphasizes targeted therapies and immunotherapies.
  2. Basic Epidemiological Studies:
    Though important, basic epidemiological studies are becoming less frequent compared to molecular and mechanistic studies that provide deeper insights into cancer biology.
  3. Single-Agent Drug Studies:
    Research focusing on the efficacy of single-agent chemotherapeutics is waning, with a shift towards combination therapies and multi-target approaches that may offer better outcomes.
  4. In Vivo Animal Models:
    While still relevant, there is a reduced emphasis on traditional in vivo animal models in favor of more sophisticated models that better mimic human disease, including organoids and patient-derived xenografts.
  5. General Cancer Prevention Strategies:
    Research that broadly addresses cancer prevention without a molecular basis is declining, as more studies focus on specific molecular pathways and targeted prevention strategies.

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