Molecular Cell

Scope & Guideline

Pioneering Discoveries in Cell and Molecular Biology.

Introduction

Welcome to the Molecular Cell information hub, where our guidelines provide a wealth of knowledge about the journal’s focus and academic contributions. This page includes an extensive look at the aims and scope of Molecular Cell, highlighting trending and emerging areas of study. We also examine declining topics to offer insight into academic interest shifts. Our curated list of highly cited topics and recent publications is part of our effort to guide scholars, using these guidelines to stay ahead in their research endeavors.
LanguageEnglish
ISSN1097-2765
PublisherCELL PRESS
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 1997 to 2024
AbbreviationMOL CELL / Mol. Cell
Frequency24 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address50 HAMPSHIRE ST, FLOOR 5, CAMBRIDGE, MA 02139

Aims and Scopes

Molecular Cell focuses on the fundamental mechanisms of molecular biology, particularly in the context of cellular processes, gene expression, and the interplay between various molecular components. This journal serves as a platform for publishing high-quality research that advances our understanding of molecular mechanisms in health and disease.
  1. Molecular Mechanisms of Gene Regulation:
    The journal emphasizes studies that elucidate how gene expression is controlled at various levels, including transcriptional regulation, RNA processing, and chromatin modifications.
  2. Cellular Stress Responses:
    Research articles often explore how cells respond to various stressors, including oxidative stress, DNA damage, and nutrient deprivation, highlighting the molecular pathways involved.
  3. Protein Dynamics and Interactions:
    Molecular Cell publishes work that investigates how proteins interact, fold, and function within cellular contexts, including the roles of molecular chaperones and post-translational modifications.
  4. CRISPR and Genome Editing Technologies:
    The journal features innovative applications and developments in CRISPR technology, focusing on its mechanisms, modifications, and implications for gene editing and therapy.
  5. Cell Fate and Developmental Biology:
    Articles related to how molecular processes influence cell differentiation, lineage specification, and developmental pathways are central to the journal's scope.
  6. Cancer Biology and Therapeutic Strategies:
    Research addressing the molecular underpinnings of cancer, including oncogenes, tumor suppressors, and therapeutic targets, is a significant focus of the journal.
Molecular Cell is currently witnessing a rise in research themes that reflect the latest advancements in molecular biology. These emerging trends indicate a shift towards more integrated and interdisciplinary approaches to understanding cellular and molecular mechanisms.
  1. Phase Separation and Biomolecular Condensates:
    Increasingly, studies are exploring the role of phase separation in cellular organization and function, particularly how biomolecular condensates influence processes like transcription and signal transduction.
  2. Epitranscriptomics and RNA Modifications:
    Research focusing on the role of RNA modifications, such as m6A methylation, in regulating gene expression and cellular responses is gaining momentum, reflecting a growing interest in the post-transcriptional landscape.
  3. Interplay Between Metabolism and Gene Regulation:
    There is a trend towards exploring how metabolic pathways intersect with gene regulatory networks, particularly in the context of cancer metabolism and cellular stress responses.
  4. Technological Innovations in CRISPR and Genome Editing:
    Advancements in CRISPR technology are leading to new applications and refinements in genome editing, which are being actively published, showcasing the journal's commitment to cutting-edge research.
  5. Immunology and Cancer Therapeutics:
    Research that connects molecular mechanisms to immune responses, particularly in the context of cancer, is increasingly prominent, reflecting the growing importance of immunotherapy in cancer treatment.

Declining or Waning

While Molecular Cell continues to publish impactful research, certain themes appear to be declining in prominence over recent years. This shift may reflect evolving scientific interests or advancements in technology that change the landscape of molecular biology research.
  1. Studies on Classical Biochemistry:
    Research focused on traditional biochemical methods and pathways has seen a decrease, as more sophisticated molecular techniques and systems biology approaches gain traction.
  2. Basic Mechanistic Studies without Broader Implications:
    There is a noticeable decline in papers that focus solely on basic mechanisms without linking them to broader biological contexts or applications, particularly in disease models.
  3. Single-Cell Analysis Techniques:
    Although single-cell technologies are still relevant, there has been a shift towards integrating multi-omic approaches rather than isolated single-cell studies, leading to fewer publications focusing exclusively on single-cell methodologies.

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