Nucleic Acid Therapeutics

Scope & Guideline

Fostering Collaboration in Nucleic Acid Therapeutics.

Introduction

Immerse yourself in the scholarly insights of Nucleic Acid Therapeutics with our comprehensive guidelines detailing its aims and scope. This page is your resource for understanding the journal's thematic priorities. Stay abreast of trending topics currently drawing significant attention and explore declining topics for a full picture of evolving interests. Our selection of highly cited topics and recent high-impact papers is curated within these guidelines to enhance your research impact.
LanguageEnglish
ISSN2159-3337
PublisherMARY ANN LIEBERT, INC
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 2011 to 2024
AbbreviationNUCLEIC ACID THER / Nucl. Acid Ther.
Frequency6 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address140 HUGUENOT STREET, 3RD FL, NEW ROCHELLE, NY 10801

Aims and Scopes

Nucleic Acid Therapeutics focuses on the development and application of nucleic acid-based therapies, particularly oligonucleotides, for treating various diseases. The journal emphasizes innovative methodologies and therapeutic strategies that leverage the unique properties of nucleic acids.
  1. Oligonucleotide Therapeutics:
    The journal primarily covers research on therapeutic oligonucleotides, including antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs), and their modifications to enhance efficacy and safety.
  2. Mechanisms of Action:
    It explores the molecular mechanisms of how nucleic acids interact with cellular machinery, including studies on RNA splicing, gene silencing, and the role of modifications on therapeutic effectiveness.
  3. Drug Development and Delivery Systems:
    Research on the preclinical and clinical development of nucleic acid therapeutics, including pharmacokinetics, biodistribution, and innovative delivery systems, is a core focus area.
  4. Clinical Applications and Innovations:
    The journal highlights clinical applications of nucleic acid therapies in treating genetic disorders, cancers, and infectious diseases, showcasing new therapeutic approaches and successes.
  5. Regulatory and Ethical Considerations:
    Discussion on the regulatory landscape, ethical considerations, and patient involvement in the development of nucleic acid therapeutics is also a significant aspect of the journal.
Nucleic Acid Therapeutics has seen a significant evolution in its focus, with several emerging themes reflecting the latest advancements and challenges in the field of nucleic acid-based therapies.
  1. RNA Modifications and Their Therapeutic Impacts:
    Recent publications emphasize the importance of RNA modifications in enhancing the therapeutic potential of oligonucleotides, indicating a trend towards optimizing oligonucleotide chemistry for improved efficacy.
  2. Personalized Medicine Approaches:
    The journal is increasingly featuring research on personalized medicine, particularly the development of individualized therapies for rare diseases and genetic disorders, demonstrating a shift towards tailored therapeutic strategies.
  3. Immunogenicity and Safety Assessments:
    There is a growing focus on assessing the immunogenicity and safety profiles of nucleic acid therapeutics, addressing concerns related to innate immune responses and off-target effects.
  4. Innovative Delivery Mechanisms:
    Emerging themes include advanced delivery mechanisms for nucleic acid therapeutics, such as the use of exosomes and targeted nanoparticles, which enhance the specificity and efficiency of therapy.
  5. In Vivo Applications and Clinical Trials:
    Increased emphasis is being placed on in vivo applications and clinical trial data, reflecting a trend towards translating laboratory findings into clinical settings, particularly for diseases like Duchenne muscular dystrophy and various cancers.

Declining or Waning

While Nucleic Acid Therapeutics continues to thrive in various areas, some themes have shown a decline in prominence in recent publications. This shift may reflect changing research priorities or advancements in related fields.
  1. Traditional Small Molecule Therapies:
    There has been a noticeable decline in research focused on traditional small molecule therapies in favor of more advanced nucleic acid-based approaches, which are now seen as more innovative and targeted.
  2. Non-Modified Oligonucleotides:
    Research on non-modified oligonucleotides has decreased as the community increasingly focuses on chemically modified oligonucleotides that offer improved stability, efficacy, and safety profiles.
  3. Conventional Delivery Methods:
    Studies exploring conventional delivery methods for oligonucleotides have become less common, as the field shifts towards developing more sophisticated delivery systems such as nanoparticles and conjugates.
  4. Basic Mechanistic Studies:
    There is a waning interest in basic mechanistic studies without translational implications, with a greater emphasis now on research that directly leads to clinical applications.

Similar Journals

Drug Target Insights

Pioneering Open Access to Critical Pharmacological Research.
Publisher: ABOUTSCIENCE SRLISSN: 1177-3928Frequency: 1 issue/year

Drug Target Insights is a prestigious peer-reviewed journal published by ABOUTSCIENCE SRL, catering to the dynamic field of pharmacology and medicinal biochemistry. With an Open Access policy since 2006, the journal aims to promote the dissemination of cutting-edge research and innovations that target drug discovery and therapeutic developments. Based in Milan, Italy, it boasts a notable impact within its research community, achieving a Q3 classification in the categories of Clinical Biochemistry and Medical Pharmacology in 2023, alongside a robust performance in the Q2 category for Pharmacology, Toxicology, and Pharmaceutics. The journal serves as a vital platform for researchers, professionals, and students seeking to advance their understanding of drug delivery systems, therapeutic targets, and pharmacodynamics. With a commitment to enhancing global access to crucial research findings, Drug Target Insights stands out as an essential resource for those engaged in the ever-evolving landscape of pharmaceutical sciences.

Molecular Therapy Nucleic Acids

Catalyzing scientific excellence in molecular medicine.
Publisher: CELL PRESSISSN: 2162-2531Frequency: 4 issues/year

Molecular Therapy Nucleic Acids is a premier open-access journal published by CELL PRESS, dedicated to advancing the field of molecular medicine through the innovative application of nucleic acid-based therapies. Since its inception in 2012, this journal has become an essential resource for researchers and professionals in drug discovery and molecular medicine, reflected in its status as a Q1 journal in both categories for 2023. With a notable impact factor and high rankings in Scopus, including #8 out of 157 in Drug Discovery and #16 out of 178 in Molecular Medicine, it serves to disseminate groundbreaking research and foster collaborations among scientists worldwide. The journal's comprehensive scope encompasses a wide variety of topics, including gene therapy, RNA interference, and CRISPR technology, ensuring that it remains at the forefront of scientific excellence. With open access availability, Molecular Therapy Nucleic Acids actively promotes the widespread dissemination of knowledge, making its crucial insights accessible to students, researchers, and industry professionals alike.

EXPERT OPINION ON THERAPEUTIC PATENTS

Decoding Drug Discovery: Insights from Leading Experts
Publisher: TAYLOR & FRANCIS LTDISSN: 1354-3776Frequency: 12 issues/year

EXPERT OPINION ON THERAPEUTIC PATENTS, published by Taylor & Francis Ltd, is a prestigious journal dedicated to the critical analysis and commentary on therapeutic patents, emphasizing their impact on drug discovery and development. With an improving reputation reflected in its 2023 Q1 rankings in Drug Discovery and Pharmacology, this journal stands out as a leading source in the fields of pharmacology and medicine, holding significant relevance with a Scopus ranking in the 90th percentile for its contributions in Drug Discovery and a robust position in Pharmacology. Launched in 1991, the journal consistently engages researchers and professionals seeking to stay at the forefront of innovations in therapeutic patents, thus driving advancements in the pharmaceutical landscape. Although it does not offer Open Access, its comprehensive scope and commitment to quality make it an essential resource for those looking to explore the intersection of intellectual property and pharmacological research.

CURRENT PHARMACEUTICAL DESIGN

Leading the Charge in Pharmaceutical Innovations
Publisher: BENTHAM SCIENCE PUBL LTDISSN: 1381-6128Frequency: 46 issues/year

CURRENT PHARMACEUTICAL DESIGN is a leading journal in the fields of Drug Discovery and Pharmacology, published by Bentham Science Publishers Ltd in the dynamic United Arab Emirates. With an impressive historical span from 1995 to 2024, this journal serves as a vital platform for disseminating innovative research findings, breakthrough methodologies, and critical reviews that shape the future of pharmaceutical sciences. Ranked Q2 in both Drug Discovery and Pharmacology categories according to the 2023 metrics, it places itself within the top-tier percentile, catering to a diverse audience of researchers, industry professionals, and students. The journal’s commitment to high-quality research exploration is evidenced by its Scopus ranking, where it is positioned favorably within its category ranks. Although currently not Open Access, CURRENT PHARMACEUTICAL DESIGN remains an essential resource for those looking to stay at the forefront of pharmacological advancements and drug development strategies.

DRUG DEVELOPMENT RESEARCH

Pioneering insights in pharmacology and toxicology.
Publisher: WILEYISSN: 0272-4391Frequency: 8 issues/year

DRUG DEVELOPMENT RESEARCH is a premier interdisciplinary journal published by Wiley, focusing on the latest advancements in drug discovery, pharmacology, and toxicology. With an ISSN of 0272-4391 and an E-ISSN of 1098-2299, this esteemed publication has been a cornerstone in the field since its inception in 1981 and continues to provide cutting-edge research until 2024. Its rigorous peer-review process and strategic placement in Q2 of the Drug Discovery category, as well as ranking #60 out of 157 in Scopus, underscore the journal's relevance and influence, boasting a respectable 62nd percentile ranking. While the journal does not currently offer open access, it remains a vital resource for researchers, professionals, and students seeking to expand their knowledge on the processes of drug development, identifying new therapeutic targets, and assessing the efficacy and safety of novel compounds. Situated in Hoboken, NJ, this journal stands at the forefront of pharmaceutical innovation, making significant contributions to the advancement of medical science.

Translational Research

Pioneering Research for Global Health Progress
Publisher: ELSEVIER SCIENCE INCISSN: 1931-5244Frequency: 12 issues/year

Translational Research, published by Elsevier Science Inc, stands at the forefront of the rapidly evolving fields of biochemistry, medicine, physiology, and public health. With an impressive 2023 Q1 ranking in these categories, this journal has established itself as a critical platform for disseminating innovative research that bridges the gap between laboratory findings and clinical application. The journal, which has been converging knowledge since 2006, is committed to advancing scientific understanding and improving health outcomes by publishing high-quality articles that reflect rigorous peer review and impactful findings. With its impressive Scopus rankings, including a rank of #5 in Biochemistry and #7 in Physiology, it is an essential resource for researchers, practitioners, and students dedicated to the translation of scientific breakthroughs into real-world health solutions. Transitioning to an open-access model, the journal enhances accessibility and engagement, inviting a global audience to participate in the discourse shaping the future of healthcare and disease management.

NATURE REVIEWS DRUG DISCOVERY

Leading the charge in pharmacological research.
Publisher: NATURE PORTFOLIOISSN: 1474-1776Frequency: 12 issues/year

Nature Reviews Drug Discovery, published by Nature Portfolio, is a premier academic journal dedicated to the field of drug discovery. Since its inception in 2002, this journal has become an essential resource for researchers, professionals, and students, providing high-quality, peer-reviewed articles that present the latest advancements and insights into the complex landscape of pharmaceutical development. With an impressive impact factor placing it in the Q1 category across multiple disciplines, including Drug Discovery and Pharmacology, it continues to lead the way in pharmacological research, evidenced by its top ranks in Scopus among peers. Although it is not an open-access publication, the journal remains a vital tool for those looking to stay abreast of emerging trends and innovations in drug research. For more details about their submission guidelines and access options, visit the official journal website.

JOURNAL OF MOLECULAR MEDICINE-JMM

Connecting Molecular Biology to Clinical Applications.
Publisher: SPRINGER HEIDELBERGISSN: 0946-2716Frequency: 12 issues/year

JOURNAL OF MOLECULAR MEDICINE (JMM) is a premier publication dedicated to advancing the field of molecular medicine, encompassing critical areas such as drug discovery, genetics, and biochemistry. Published by Springer Heidelberg in Germany, this influential journal has established its significance within the academic community, achieving an impressive Q1 ranking across multiple categories as of 2023, including Drug Discovery, Clinical Genetics, and Molecular Medicine. With a focus on publishing high-quality research and novel insights, JMM appeals to a diverse audience of researchers, professionals, and students passionate about the molecular underpinnings of health and disease. The journal, which has seen a convergence of relevant research spanning from 1976 to 2024, is instrumental in showcasing groundbreaking studies that push the boundaries of knowledge in molecular therapeutics and biomedical science. While it does not offer open access, the rigor of its peer-reviewed content ensures that each publication is a valuable addition to the scientific discourse surrounding molecular medicine. For comprehensive studies and reviews that highlight the intersection of molecular biology and clinical application, look no further than JOURNAL OF MOLECULAR MEDICINE.

Discovery Medicine

Fostering a vibrant dialogue in the world of medical sciences.
Publisher: DISCOVERY MEDICINEISSN: 1539-6509Frequency: 6 issues/year

Discovery Medicine, an esteemed journal published by Discovery Medicine, serves as a vital platform within the field of general medicine, dedicated to advancing knowledge through high-quality research and innovative insights. With its ISSN 1539-6509 and E-ISSN 1944-7930, this journal boasts an impressive Scopus ranking of #29 out of 529 in the general medicine category, positioning it at the 94th percentile, indicating its significant contribution to the medical sciences. While operating as a subscription-based journal, Discovery Medicine fosters an environment where researchers and professionals can disseminate their findings and engage with cutting-edge developments in medicine. Spanning topics that bridge clinical practice and healthcare advancements, this journal aims to inform, challenge, and inspire the medical community. The journal has converged its volumes from 2006 to 2007 and again from 2009 to 2018, highlighting its sustained commitment to excellence even as coverage has temporarily discontinued in Scopus. Situated at 10 Gerard Ave, Ste 201, Timonium, MD 21093, Discovery Medicine continues to be a cornerstone for medical scholars, offering a rich repository of knowledge essential for ongoing research and practical applications.

CURRENT TOPICS IN MEDICINAL CHEMISTRY

Transforming Challenges into Solutions in Medicinal Chemistry
Publisher: BENTHAM SCIENCE PUBL LTDISSN: 1568-0266Frequency: 32 issues/year

CURRENT TOPICS IN MEDICINAL CHEMISTRY is a prestigious journal published by Bentham Science Publishers Ltd, dedicated to advancing the field of medicinal chemistry through the dissemination of high-quality research from 2001 to 2024. With an ISSN of 1568-0266 and an E-ISSN of 1873-4294, this journal is recognized for its significant contributions, as evidenced by its Scopus ranking in the 63rd percentile in the category of Drug Discovery, specifically at position #58 out of 157. Currently placed in Quartile 3 within Drug Discovery and Quartile 2 in miscellaneous medicine as of 2023, it serves as an essential resource for researchers, professionals, and students interested in the latest developments, methodologies, and applications in medicinal chemistry. The journal aims to foster collaboration and innovation by featuring original research articles, reviews, and brief communications that address current and emerging challenges in the discipline. Although it is not an open access platform, the journal's rich content is indispensable for those striving to enhance therapeutic strategies and drug development processes.