Molecular Therapy Nucleic Acids
Scope & Guideline
Catalyzing scientific excellence in molecular medicine.
Introduction
Aims and Scopes
- Gene Editing Technologies:
This area encompasses advancements in CRISPR, TALENs, and other gene editing techniques aimed at correcting genetic disorders, improving genomic stability, and developing novel therapeutic strategies. - Nucleic Acid Delivery Systems:
Research in this scope focuses on the development of novel carriers and delivery mechanisms, such as lipid nanoparticles, exosomes, and viral vectors, to enhance the cellular uptake and efficacy of nucleic acid therapeutics. - RNA Therapeutics:
The journal emphasizes the therapeutic potentials of various RNA molecules, including mRNA, siRNA, and circular RNAs, exploring their roles in gene regulation, disease treatment, and potential applications in cancer and genetic disorders. - Mechanisms of Action and Safety:
Research that investigates the mechanisms through which nucleic acid therapies exert their effects and the safety profiles of these treatments, including off-target effects and immune responses. - Translational Research:
The journal also focuses on the translation of basic research findings into clinical applications, emphasizing studies that bridge laboratory discoveries with patient care.
Trending and Emerging
- Enhanced CRISPR-Cas9 Techniques:
Recent publications highlight advancements in CRISPR-Cas9 technology, including improved specificity and efficiency, as well as novel applications in gene therapy for complex diseases. - RNA Modifications and Their Therapeutic Implications:
There is an increasing focus on understanding how RNA modifications, such as m6A, influence the stability and function of therapeutic RNAs, opening new avenues for enhancing RNA-based therapies. - Circular RNAs as Therapeutics:
Research into the therapeutic potential of circular RNAs is gaining momentum, exploring their roles in disease mechanisms and their utility as novel therapeutic agents. - AI and Machine Learning in RNA Research:
The integration of artificial intelligence and machine learning techniques in the design and optimization of RNA therapeutics is emerging as a significant trend, showcasing the potential for computational approaches to enhance nucleic acid therapy development. - Exosome-Mediated Delivery Systems:
Publications are increasingly focusing on exosomes as natural carriers for delivering RNA therapeutics, capitalizing on their biocompatibility and ability to evade immune detection.
Declining or Waning
- Traditional Gene Therapy Approaches:
There is a noticeable decline in research focused on older gene therapy methods that do not utilize contemporary techniques such as CRISPR or innovative delivery systems. This shift reflects the field's movement towards more advanced technologies. - Basic Mechanistic Studies of RNA Interference:
Studies that focus solely on the fundamental aspects of RNA interference without translational applications are becoming less common, as the field increasingly prioritizes applied research with direct therapeutic implications. - In Vivo Models in Preclinical Studies:
Research utilizing traditional animal models for initial testing of nucleic acid therapies may be waning, as there is a growing trend towards more sophisticated models, such as organoids or humanized systems, that better mimic human pathophysiology.
Similar Journals
Biomolecules
Where groundbreaking research meets open access knowledge.Biomolecules is a prestigious, peer-reviewed journal published by MDPI that has been dedicated to advancing the field of biochemical research since its launch in 2011. With an impressive impact factor positioning it in Q1 for Biochemistry and Q2 for Molecular Biology as of 2023, this journal serves as a vital platform for disseminating high-quality research findings related to biological macromolecules, including proteins, nucleic acids, and carbohydrates. Operating as an Open Access journal, it ensures that vital research is accessible to all, furthering knowledge dissemination and collaboration within the scientific community. Located in Basel, Switzerland, the journal has established a significant presence in major academic databases, holding commendable Scopus rankings in both Biochemistry and Molecular Biology. Researchers, professionals, and students will find Biomolecules an invaluable resource for cutting-edge research, reviews, and insights in the rapidly evolving domains of biochemistry and molecular biology.
TRENDS IN PHARMACOLOGICAL SCIENCES
Elevating Standards in Pharmacology and Toxicology ResearchTRENDS IN PHARMACOLOGICAL SCIENCES, an esteemed journal published by CELL PRESS, is a leading platform in the field of pharmacology and toxicology, with an impressive history since its inception in 1979. With an impact factor that places it in the top quartile category (Q1) for both pharmacology and toxicology as of 2023, it is recognized for disseminating high-quality, peer-reviewed research that shapes the future of these disciplines. The journal is indexed with a robust standing in Scopus rankings, positioned at rank #2 in Toxicology and #6 in Pharmacology, both boasting an extraordinary percentile of 98. Researchers, professionals, and students benefit from its comprehensive coverage, which spans cutting-edge advancements, review articles, and significant trends in drug development and toxicity assessment. While the journal does not currently offer open access options, it remains a vital resource for the academic community, ensuring critical insights into the complexities of pharmacological sciences are readily available to enhance research and practice.
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
Advancing ocular health through innovative research.JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, published by Mary Ann Liebert, Inc, stands at the forefront of research in the realms of ophthalmology and pharmacology. Established in 1985 and converging until 2024, this esteemed journal is dedicated to advancing the understanding of ocular pharmacology, drug therapies, and therapeutic approaches in the treatment of eye diseases. With an impressive impact factor and categorized in the Q2 quartile for both Ophthalmology and Medical Pharmacology, it showcases pivotal research in the field, reflecting its rank of #31 among 137 in Ophthalmology and #109 among 272 in Medical Pharmacology per Scopus metrics. Although it follows a subscription-based model, the journal provides critical insights and empirical studies that foster innovation and collaboration for researchers, professionals, and students alike in the pursuit of improving ocular health.
CELLULAR & MOLECULAR BIOLOGY LETTERS
Unlocking the Secrets of Life at the Molecular LevelCELLULAR & MOLECULAR BIOLOGY LETTERS, published by BMC, is a premier open-access journal dedicated to disseminating high-quality research in the fields of Biochemistry, Cell Biology, and Molecular Biology. Established in 1996, the journal has emerged as a leader in its domain, boasting an impressive Q1 ranking across three critical categories as of 2023, reflecting its significant impact within the scientific community. With an ISSN of 1425-8153 and an E-ISSN of 1689-1392, it offers accessible research findings to a global audience, having been open access since 2013. Situated in the United Kingdom, at CAMPUS, 4 CRINAN ST, LONDON N1 9XW, the journal continues to serve as a vital resource for researchers, professionals, and students, contributing to advancements in the understanding of cellular and molecular processes. By providing a platform for original research, reviews, and short communications, CELLULAR & MOLECULAR BIOLOGY LETTERS plays a crucial role in fostering dialogue and collaboration within the scientific community.
JOURNAL OF GENE MEDICINE
Connecting Researchers to Transformative Genetic InsightsThe Journal of Gene Medicine, published by Wiley, stands as a pivotal resource in the field of gene therapy and molecular medicine, with a rich history of dissemination of impactful research since its inception in 1998. With an ISSN of 1099-498X and an E-ISSN of 1521-2254, this esteemed journal plays a crucial role in advancing our understanding of genetics and drug discovery, reflected in its impressive 2023 Scopus rankings where it holds a Q2 classification in Drug Discovery and Q3 in several genetics-related categories. The journal aims to facilitate the exchange of high-quality research findings that bridge the gap between laboratory and clinical applications, making it an essential platform for researchers, academics, and healthcare professionals committed to the forefront of genetic innovation. Although it does not currently offer open access options, its reputation for rigorous peer review ensures that all published work meets the highest academic standards, providing a reliable reference for scientific inquiry in the United States and beyond. As the field rapidly evolves, the Journal of Gene Medicine remains at the helm, guiding future discoveries with its influential publications and comprehensive insights.
Non-Coding RNA
Fostering Collaboration in Non-Coding RNA ExplorationNon-Coding RNA is a prestigious open-access journal published by MDPI, based in Switzerland, dedicated to the significant and rapidly evolving field of non-coding RNA research. Established in 2015, this journal has quickly become an essential resource for researchers and professionals, showcasing innovative studies and breakthroughs related to the functions and mechanisms of non-coding RNAs in various biological processes. With an impressive Q1 ranking in Biochemistry and strong rankings in Genetics and Molecular Biology, Non-Coding RNA consistently reflects the highest standards of academic publishing. The journal provides comprehensive access options, granting researchers worldwide the ability to disseminate and access high-quality research without subscription barriers. As the landscape of genomics and molecular discoveries continues to expand, the journal aims to foster interdisciplinary exchanges and collaborations, making it a vital platform for advancing knowledge and innovation in this critical area of biological science.
NUCLEIC ACIDS RESEARCH
Exploring the Frontiers of Genetic DiscoveryNUCLEIC ACIDS RESEARCH, published by Oxford University Press, is a premier peer-reviewed journal in the field of genetics, holding a prestigious Q1 ranking in this domain as of 2023. Since its inception in 1974 and with a converged publication horizon extending to 2024, this journal has established itself as a vital resource for researchers and professionals interested in the molecular aspects of nucleic acids, encompassing DNA and RNA studies as well as their implications in biochemistry and molecular biology. With an impressive Scopus rank of #6 out of 347 in Genetics, this journal is positioned in the 98th percentile among its peers, highlighting its significant impact and relevance in the scientific community. As an open access journal since 2005, NUCLEIC ACIDS RESEARCH ensures wide dissemination of knowledge, promoting collaborative advancements in genetic research. For those looking to stay at the forefront of nucleic acid research, this journal remains an essential publication for accessing cutting-edge findings and innovative methodologies in the field.
RSC Chemical Biology
Advancing Interdisciplinary Discoveries in Life SciencesRSC Chemical Biology is a prestigious journal published by the Royal Society of Chemistry, providing a significant platform for researchers in the fields of biochemistry, genetics, and molecular biology. Launched in 2020, the journal aims to disseminate high-quality research that bridges the gap between chemistry and biology, promoting interdisciplinary studies and innovations that are essential for advancements in life sciences. With an emerging impact factor and ranking in the top quartile (Q1) for multiple categories such as Biochemistry and Molecular Biology, RSC Chemical Biology holds a prominent position in the academic landscape, evidenced by its Scopus rankings placing it in the top 20% and 30% of its respective fields. Although it does not operate under an open-access model, the journal's commitment to accessibility is reflected in its rigorous peer-review process and its role in shaping future scientific discourse. Research published in this journal is vital for contributing to our understanding of complex biological processes and fostering innovations that can lead to real-world applications.
EMBO REPORTS
Advancing Molecular Biology Through Rigorous ResearchEMBO REPORTS, published by WILEY, is a premier journal in the fields of Biochemistry, Genetics, and Molecular Biology, recognized for its rigorous peer-review process and impactful scientific contributions. Established in the year 2000 in the United Kingdom, this journal has maintained a stellar reputation, reflected in its consistent positioning within the Q1 category across these disciplines as of 2023. EMBO REPORTS excels in disseminating high-quality and timely research that addresses fundamental questions and challenges in molecular biology and genetics, making it an invaluable resource for researchers, professionals, and students. With impressive Scopus rankings, including Genetics at the 32nd rank and a 90th percentile placement, it fosters an environment for scholarly exchange and advances in knowledge. While Open Access options are not available, the journal continues to enhance its impact through traditional subscription models, thereby maintaining wide visibility in the scientific community. Its ongoing evolution promises continued relevance and influence until at least 2024.
CURRENT GENE THERAPY
Shaping Tomorrow’s Therapies Today.CURRENT GENE THERAPY is a leading journal in the field of gene therapy, offering a platform for researchers and professionals to publish their findings related to innovative approaches in gene-based treatments. Published by Bentham Science Publishers Ltd, this journal, with its ISSN 1566-5232 and E-ISSN 1875-5631, is indexed in respected databases, enhancing its visibility and impact in the scientific community. As of 2023, it holds a commendable impact factor, with categorized quartile rankings reflecting its influence, especially in Drug Discovery (Q2), Genetics (Q3), and Molecular Medicine (Q3). Although it follows a subscription model, the journal aims to bridge the gap between laboratory research and clinical applications, attracting submissions that provide critical insights into gene therapy advancements from 2001 to 2024. The editorial scope covers various aspects of gene therapy, including experimental studies and clinical trials, underlining its commitment to fostering knowledge that addresses genetic disorders and enhances therapeutic efficacy. Whether you are a researcher, clinician, or student, CURRENT GENE THERAPY serves as an invaluable resource at the forefront of genetic research and medical innovation.