RSC Medicinal Chemistry

Scope & Guideline

Connecting Disciplines for Breakthrough Medicines

Introduction

Welcome to the RSC Medicinal Chemistry information hub, where our guidelines provide a wealth of knowledge about the journal’s focus and academic contributions. This page includes an extensive look at the aims and scope of RSC Medicinal Chemistry, highlighting trending and emerging areas of study. We also examine declining topics to offer insight into academic interest shifts. Our curated list of highly cited topics and recent publications is part of our effort to guide scholars, using these guidelines to stay ahead in their research endeavors.
LanguageEnglish
ISSN-
PublisherROYAL SOC CHEMISTRY
Support Open AccessNo
Country-
Type-
Converge-
AbbreviationRSC MED CHEM / RSC Med. Chem.
Frequency12 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
AddressTHOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND

Aims and Scopes

RSC Medicinal Chemistry is dedicated to advancing the field of medicinal chemistry through innovative research that encompasses the design, synthesis, and evaluation of new chemical entities with therapeutic potential. The journal focuses on the integration of experimental and computational approaches to facilitate drug discovery and development.
  1. Drug Discovery and Development:
    The journal emphasizes research that contributes to the understanding and development of new therapeutic agents, including small molecules, biologics, and novel drug delivery systems.
  2. Targeted Therapeutics:
    There is a strong focus on the design and synthesis of compounds aimed at specific biological targets, including proteins involved in cancer, infectious diseases, and metabolic disorders.
  3. Mechanistic Studies:
    Papers often explore the mechanisms of action of new compounds, providing insights into their pharmacological effects and potential therapeutic applications.
  4. Novel Synthetic Methodologies:
    RSC Medicinal Chemistry showcases innovative synthetic strategies that facilitate the creation of complex molecular structures, enhancing the efficiency and effectiveness of drug development processes.
  5. Interdisciplinary Approaches:
    The journal encourages interdisciplinary research that combines medicinal chemistry with biology, pharmacology, and computational modeling to address complex challenges in drug development.
RSC Medicinal Chemistry has identified several trending and emerging themes in recent years, reflecting the dynamic nature of medicinal chemistry research and the need to address contemporary health challenges.
  1. PROTAC Technology:
    The use of PROTACs (Proteolysis Targeting Chimeras) is gaining momentum, with increasing publications focusing on their design and application in targeted protein degradation, offering novel therapeutic strategies for various diseases.
  2. Nanotechnology in Drug Delivery:
    There is a rising interest in the application of nanotechnology for drug delivery systems, enhancing the bioavailability and targeting capabilities of therapeutic agents.
  3. Machine Learning and AI in Drug Design:
    The integration of machine learning and artificial intelligence in drug discovery processes is emerging as a significant trend, facilitating the prediction of molecular properties and optimizing lead compounds.
  4. Immunotherapy and Immune Modulation:
    Research on immunotherapeutics, particularly in cancer treatment, is trending, with an emphasis on small molecules that can modulate immune responses to enhance therapeutic efficacy.
  5. Antimicrobial Resistance Solutions:
    Given the global health crisis posed by antimicrobial resistance, there is an increasing focus on discovering new classes of antibiotics and strategies to overcome resistance mechanisms.

Declining or Waning

As the journal evolves, certain themes have seen a decrease in prominence in recent publications. This waning focus reflects the shifting priorities and emerging interests within the field of medicinal chemistry.
  1. Traditional Natural Product Studies:
    While natural products have historically played a significant role in drug discovery, there is a noticeable decline in papers solely focused on traditional natural product chemistry, as researchers increasingly explore synthetic and semi-synthetic alternatives.
  2. Basic In Vitro Assays:
    There is a diminishing emphasis on basic in vitro assays without mechanistic insights, as the field increasingly values studies that incorporate more complex biological systems and translational relevance.
  3. Single Target Inhibition Studies:
    Research centered on single-target inhibitors is becoming less common, with a shift towards multitarget approaches and the development of compounds that can modulate multiple pathways simultaneously.

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