Particle and Fibre Toxicology
Scope & Guideline
Connecting science to toxicological realities.
Introduction
Aims and Scopes
- Toxicological Assessments of Particulate Matter:
The journal frequently publishes research examining the toxicological effects of various particulate matter, including nanoparticles and fibers, on biological systems, emphasizing methodologies such as in vivo and in vitro studies. - Mechanistic Insights into Particle-Induced Toxicity:
Research articles often delve into the cellular and molecular mechanisms through which particulate matter induces toxicity, inflammation, and other adverse health effects, contributing to a deeper understanding of these processes. - Multidisciplinary Approaches to Nanotoxicology:
The journal encourages studies that utilize multidisciplinary approaches, integrating toxicology, pharmacokinetics, and epidemiology to assess risks associated with exposure to engineered nanomaterials and environmental pollutants. - Impact of Environmental and Dietary Factors on Toxicity:
There is a consistent focus on how environmental pollutants, including diesel exhaust and microplastics, interact with dietary factors to influence health outcomes, particularly in vulnerable populations. - Innovative Methodologies for Risk Assessment:
The journal highlights innovative methodologies for risk assessment, including high-throughput screening and omics technologies, to evaluate the health effects of emerging particulate contaminants.
Trending and Emerging
- Microplastics and Their Health Impacts:
Research on the health effects of microplastics has surged, reflecting growing public and scientific concern over their ubiquitous presence in the environment and potential toxicity. - Nanomaterials and Targeted Toxicity Mechanisms:
A significant increase in studies focusing on the specific mechanisms of toxicity associated with various nanomaterials, including their interactions at the cellular level, has been noted, indicating a deeper exploration of their health risks. - Impact of Environmental Pollutants on Chronic Diseases:
Emerging themes are focusing on the links between exposure to environmental pollutants, such as diesel exhaust, and chronic diseases, including cardiovascular conditions and metabolic disorders, emphasizing the long-term health implications. - Sex Differences in Toxicological Responses:
There is a growing interest in understanding the role of sex differences in the toxicological responses to particulate matter, as evidenced by studies examining how hormonal variations affect susceptibility to toxicity. - Integrated Risk Assessment Frameworks:
The development and application of integrated risk assessment frameworks that combine data from various sources, including epidemiological studies and mechanistic insights, are becoming increasingly prominent, signaling a shift towards holistic approaches in toxicology.
Declining or Waning
- Traditional Toxicology Studies Without Modern Techniques:
There is a noticeable decrease in the publication of studies relying solely on traditional toxicology methods without integrating modern techniques such as omics approaches or advanced imaging, indicating a shift towards more innovative methodologies. - Limited Focus on Non-Respiratory Health Effects:
Research specifically targeting non-respiratory health impacts of particulate matter exposure, such as gastrointestinal or skin effects, has become less frequent, suggesting a narrowing of focus towards pulmonary and systemic effects. - Studies Concentrating Solely on In Vitro Models:
The publication of studies that exclusively utilize in vitro models without corroborating in vivo findings has diminished, reflecting a preference for comprehensive studies that bridge laboratory results with real-world implications.
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