TOXICOLOGY AND APPLIED PHARMACOLOGY

Scope & Guideline

Navigating the Nexus of Safety and Efficacy

Introduction

Welcome to the TOXICOLOGY AND APPLIED PHARMACOLOGY information hub, where our guidelines provide a wealth of knowledge about the journal’s focus and academic contributions. This page includes an extensive look at the aims and scope of TOXICOLOGY AND APPLIED PHARMACOLOGY, highlighting trending and emerging areas of study. We also examine declining topics to offer insight into academic interest shifts. Our curated list of highly cited topics and recent publications is part of our effort to guide scholars, using these guidelines to stay ahead in their research endeavors.
LanguageEnglish
ISSN0041-008x
PublisherACADEMIC PRESS INC ELSEVIER SCIENCE
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 1959 to 2024
AbbreviationTOXICOL APPL PHARM / Toxicol. Appl. Pharmacol.
Frequency24 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address525 B ST, STE 1900, SAN DIEGO, CA 92101-4495

Aims and Scopes

The journal 'Toxicology and Applied Pharmacology' focuses on the intersection of toxicology and pharmacology, aiming to disseminate significant findings that enhance understanding of the toxic effects of chemical substances and their therapeutic applications. It encompasses a wide range of studies that elucidate mechanisms of toxicity, drug safety, and the pharmacological effects of various compounds.
  1. Chemical Toxicology:
    Research exploring the toxic effects of chemicals on biological systems, including mechanisms of action, dose-response relationships, and the implications of exposure to environmental pollutants.
  2. Pharmacology and Drug Safety:
    Studies investigating the pharmacological properties of drugs, including their therapeutic potential, side effects, and safety profiles in both clinical and preclinical settings.
  3. Developmental and Reproductive Toxicology:
    Research focused on the impact of toxic substances on developmental processes and reproductive health, particularly studies examining maternal exposure and its effects on offspring.
  4. Environmental Toxicology:
    Exploration of the effects of environmental contaminants on human health and ecosystems, including studies on heavy metals, pesticides, and industrial chemicals.
  5. Cellular and Molecular Mechanisms:
    Investigations into the cellular and molecular pathways affected by toxicants, including studies on oxidative stress, apoptosis, and inflammation.
  6. Innovative Testing Methods:
    Development and application of novel in vitro and in vivo models for assessing toxicity, including high-throughput screening methods and computational toxicology.
The journal has shown a clear trajectory towards embracing new and innovative research areas that reflect the evolving landscape of toxicology and pharmacology. This section highlights the emerging themes that have gained traction in recent publications.
  1. Nanotoxicology:
    Research focusing on the toxicity of nanoparticles and nanomaterials is on the rise, driven by the increasing use of nanotechnology in medicine and industry.
  2. Pharmacogenomics:
    Studies exploring the genetic factors that influence individual responses to drugs are gaining prominence, reflecting a broader interest in personalized medicine and tailored therapeutic strategies.
  3. Microbiome Interactions:
    Emerging research on the role of the microbiome in modulating toxicological outcomes and drug metabolism is becoming increasingly prominent, linking gut health to overall pharmacological effects.
  4. Environmental Health and Epidemiology:
    There is an increasing trend towards studies that connect environmental exposures to health outcomes, particularly in the context of chronic diseases and public health.
  5. Integrated Approaches to Toxicology:
    A significant shift towards integrated methodologies that combine in vitro, in vivo, and computational approaches to assess the toxicity of compounds and mixtures is evident, reflecting the complexity of real-world exposures.

Declining or Waning

Over recent years, certain themes within the journal have seen a decline in prominence, reflecting shifts in research focus and emerging scientific priorities. This section identifies areas that are becoming less frequently addressed in the journal's publications.
  1. Traditional Toxicology:
    Research centered on classical toxicology principles, such as acute toxicity testing, has decreased as the field shifts towards more integrated approaches that include molecular and systems toxicology.
  2. Single Agent Studies:
    There is a waning interest in studies focusing exclusively on the toxic effects of single agents, as the field increasingly emphasizes the importance of understanding interactions and cumulative effects of multiple exposures.
  3. Historical Toxicological Assessments:
    Research focused on historical assessments of well-established toxicants is declining, as the journal moves towards more contemporary and relevant studies that address current public health concerns.
  4. Animal Models in Toxicology:
    While animal studies remain important, there is a notable decrease in traditional animal model studies as researchers adopt more humane and efficient in vitro techniques and computer modeling approaches.

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