PLoS Genetics

Scope & Guideline

Connecting the dots in genetics for transformative research.

Introduction

Immerse yourself in the scholarly insights of PLoS Genetics with our comprehensive guidelines detailing its aims and scope. This page is your resource for understanding the journal's thematic priorities. Stay abreast of trending topics currently drawing significant attention and explore declining topics for a full picture of evolving interests. Our selection of highly cited topics and recent high-impact papers is curated within these guidelines to enhance your research impact.
LanguageEnglish
ISSN1553-7404
PublisherPUBLIC LIBRARY SCIENCE
Support Open AccessYes
CountryUnited States
TypeJournal
Convergefrom 2005 to 2024
AbbreviationPLOS GENET / PLoS Genet.
Frequency12 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address1160 BATTERY STREET, STE 100, SAN FRANCISCO, CA 94111

Aims and Scopes

PLoS Genetics is a leading journal dedicated to the publication of research in all areas of genetics, emphasizing the integration of genetic data with biological insights. It aims to disseminate significant findings that advance our understanding of genetic mechanisms and their implications in health, evolution, and biodiversity.
  1. Genetic Mechanisms and Pathways:
    Focus on elucidating the molecular mechanisms of gene function, regulation, and interaction, including pathways that influence development, disease, and cellular processes.
  2. Population and Evolutionary Genetics:
    Exploration of genetic diversity, population structure, and evolutionary dynamics among different species, emphasizing the role of genetics in adaptation and speciation.
  3. Genomics and Transcriptomics:
    Integration of high-throughput genomic and transcriptomic data to uncover gene expression patterns, regulatory networks, and their implications for phenotypic variation.
  4. Model Organisms and Experimental Genetics:
    Utilization of model organisms (e.g., Drosophila, C. elegans, yeast) to study genetic functions, interactions, and the impact of genetic variations on development and health.
  5. Clinical Genetics and Disease Mechanisms:
    Investigation of genetic variants linked to human diseases, including the mechanisms underlying genetic disorders and the potential for therapeutic interventions.
  6. Bioinformatics and Computational Genetics:
    Development and application of computational tools and statistical methods for analyzing genetic data, facilitating insights into complex traits and disease associations.
The landscape of genetics research is constantly evolving, with emerging themes reflecting new technologies and shifting scientific interests. PLoS Genetics is at the forefront of these trends, providing insights into contemporary genetic research.
  1. CRISPR and Genome Editing Technologies:
    The application of CRISPR and other genome editing technologies has surged, leading to innovative approaches in functional genomics, gene therapy, and genetic engineering.
  2. Epigenetics and Gene Regulation:
    Increased focus on epigenetic modifications and their role in gene regulation, development, and disease, highlighting the complex interplay between genetics and environmental factors.
  3. Integrative Genomics and Multi-Omics Approaches:
    Growing interest in integrative genomics that combines data from genomics, transcriptomics, proteomics, and metabolomics to provide a holistic view of biological processes.
  4. Population Genomics and Evolutionary Biology:
    A rise in studies examining population genomics, particularly in relation to adaptation, migration, and the effects of climate change on genetic diversity.
  5. Machine Learning in Genetic Research:
    The utilization of machine learning algorithms to analyze genetic data is expanding, enhancing the ability to identify patterns and predict outcomes in complex traits and diseases.

Declining or Waning

While PLoS Genetics continues to thrive in numerous research areas, certain themes have seen a decline in frequency or focus over recent years. These waning scopes highlight shifts in research priorities and emerging interests in the field.
  1. Classical Mendelian Genetics:
    Research focusing solely on classical Mendelian principles has decreased, as the field has increasingly shifted towards complex trait analysis and polygenic models.
  2. Single-Variant Analyses:
    The emphasis on studying single genetic variants in isolation has waned in favor of understanding gene-gene interactions and the polygenic nature of traits and diseases.
  3. Static Genetic Models:
    The use of static models that do not incorporate environmental interactions or dynamic evolutionary processes is becoming less common as researchers adopt more integrative and adaptive approaches.
  4. Laboratory-Only Studies:
    Research that solely relies on laboratory conditions without considering ecological or environmental contexts is declining as the importance of field studies and real-world applications gains recognition.
  5. Focus on Non-Coding RNAs:
    While still significant, the intense focus on non-coding RNAs as standalone subjects has lessened as interest broadens to include their roles within larger genetic and epigenetic networks.

Similar Journals

MOLECULAR GENETICS AND GENOMICS

Empowering Research Through Open Access Knowledge
Publisher: SPRINGER HEIDELBERGISSN: 1617-4615Frequency: 6 issues/year

MOLECULAR GENETICS AND GENOMICS is a distinguished journal published by SPRINGER HEIDELBERG that serves as a pivotal platform for the communication of cutting-edge research and developments in the fields of genetics, molecular biology, and medicine. With an ISSN of 1617-4615 and an E-ISSN of 1617-4623, this journal has established itself since its inception in 1994 as a significant resource for researchers aiming to explore the complexities of genetic interactions and their implications in various biological systems. The journal is indexed in Scopus, with respectable rankings in the Genetics, Molecular Biology, and Biochemistry categories, showcasing its position within the academic community. It is categorized in the 2023 rankings as Q3 in Genetics, Q2 in Medicine (miscellaneous), and Q3 in Molecular Biology, indicating its relevance and quality in the scientific discourse. The journal also promotes open access, ensuring that researchers and professionals can easily share and advance knowledge in the rapidly evolving disciplines of molecular genetics and genomics. As the journal continues to bridge the gap between experimental and theoretical research, it presents a vital space for innovation, fostering collaborations and scholarly exchange among its readership.

NATURE REVIEWS GENETICS

Illuminating the Pathways of Genetic Research.
Publisher: NATURE PORTFOLIOISSN: 1471-0056Frequency: 12 issues/year

NATURE REVIEWS GENETICS, published by NATURE PORTFOLIO, stands as a leading journal in the field of genetics, boasting a remarkable reputation reflected in its Q1 ranking across multiple categories including Genetics, Clinical Genetics, and Molecular Biology. With an impressive percentile of 99th in both Genetics and Clinical Genetics, as well as a solid rank in Molecular Biology, this journal is pivotal for researchers, professionals, and students alike who seek to stay informed on the latest advancements and comprehensive reviews in genetic research. The journal's scope encompasses a wide array of topics, providing in-depth insights from fundamental genetic principles to clinical applications, underscoring its importance in bridging basic science and medical practice. Though not an open-access publication, it remains accessible through various academic institutions, enhancing its reach and influence within the scientific community. With publication years spanning from 2000 to 2024, NATURE REVIEWS GENETICS continues to shape the future of genetics research and education.

TRENDS IN GENETICS

Advancing the Frontiers of Genetic Research
Publisher: CELL PRESSISSN: 0168-9525Frequency: 12 issues/year

TRENDS IN GENETICS, published by CELL PRESS, is a leading journal in the field of genetics, recognized for its significant impact on research and advancements in the discipline. With an impressive Scopus ranking of #10 out of 347 in the category of Genetics and a 97th percentile ranking, this journal stands as a premier platform for publishing innovative, high-quality articles that shape the future of genetic research. Since its inception in 1985, TRENDS IN GENETICS has been at the forefront of the genetic sciences, continuously disseminating crucial findings while maintaining a strong commitment to scientific rigor and integrity. Although it does not currently offer open access options, its rigorous peer-review process ensures that only the most relevant and groundbreaking studies make it to publication. Scholars and practitioners in genetics will find this journal to be an invaluable resource for keeping abreast of the latest developments, trends, and methodologies that drive the field forward.

JOURNAL OF GENETICS

Fostering Innovation in Genetic Science
Publisher: INDIAN ACAD SCIENCESISSN: 0022-1333Frequency: 1 issue/year

JOURNAL OF GENETICS, published by the Indian Academy of Sciences, is a pivotal platform for researchers and scholars in the field of genetics. With its long-standing history dating back to 1910, this journal has consistently contributed to the academic discourse through the rigorous publication of original research, reviews, and case studies. Despite its current classification in the Q4 quartile for the 2023 metrics in Genetics, the journal plays a critical role in advancing our understanding of genetic principles, experimental methodologies, and innovations. Spanning a diverse array of topics, the journal aims to foster scholarly exchange and collaboration within the global genetics community. For researchers aiming to publish their work, accessing the journal’s comprehensive archives, which include publications from as early as 1910 to the present day, offers a valuable perspective on the evolution of genetic research. As it continues to adapt to the changing landscape of scientific inquiry, JOURNAL OF GENETICS remains a significant resource for students, professionals, and academics dedicated to exploring the complexities of genetics.

JOURNAL OF GENE MEDICINE

Advancing the Frontiers of Gene Therapy
Publisher: WILEYISSN: 1099-498XFrequency: 12 issues/year

The Journal of Gene Medicine, published by Wiley, stands as a pivotal resource in the field of gene therapy and molecular medicine, with a rich history of dissemination of impactful research since its inception in 1998. With an ISSN of 1099-498X and an E-ISSN of 1521-2254, this esteemed journal plays a crucial role in advancing our understanding of genetics and drug discovery, reflected in its impressive 2023 Scopus rankings where it holds a Q2 classification in Drug Discovery and Q3 in several genetics-related categories. The journal aims to facilitate the exchange of high-quality research findings that bridge the gap between laboratory and clinical applications, making it an essential platform for researchers, academics, and healthcare professionals committed to the forefront of genetic innovation. Although it does not currently offer open access options, its reputation for rigorous peer review ensures that all published work meets the highest academic standards, providing a reliable reference for scientific inquiry in the United States and beyond. As the field rapidly evolves, the Journal of Gene Medicine remains at the helm, guiding future discoveries with its influential publications and comprehensive insights.

HEREDITY

Illuminating Genetic Pathways: Your Source for Cutting-edge Research
Publisher: SPRINGERNATUREISSN: 0018-067XFrequency: 12 issues/year

HEREDITY is a prestigious academic journal published by SpringerNature, specializing in the dynamic fields of Genetics and Genetics (Clinical). With a history of excellence since its inception in 1947, this journal has established itself as a significant contributor to the understanding of genetic research, addressing both foundational principles and clinical applications. Operating without an open access model, it maintains a strong reputation with an impact factor that reflects its rigorous peer-review process and high-quality submissions, ranking in the top quartiles of its category as evidenced by its Q2 classification in Genetics and Genetics (clinical) for 2023. Further, HEREDITY holds commendable positions in Scopus rankings, illustrating its influence within the field, currently placed #21 out of 99 in Medicine (Clinical Genetics) and #87 out of 347 in Biochemistry, Genetics, and Molecular Biology (Genetics). Researchers, professionals, and students are invited to explore the latest discoveries and advancements in genetics through this esteemed journal, contributing to the broader discourse and innovation within the field.

Frontiers in Genetics

Transforming Genetic Discoveries into Solutions
Publisher: FRONTIERS MEDIA SAISSN: Frequency: 1 issue/year

Frontiers in Genetics is a premier academic journal dedicated to advancing the field of genetics through high-quality, peer-reviewed research. Published by FRONTIERS MEDIA SA in Switzerland since 2010, this Open Access journal provides a platform for researchers and practitioners to disseminate innovative findings across various subfields, including clinical genetics and molecular medicine. With a notable emphasis on interdisciplinary approaches, the journal holds a strong position in the academic landscape, achieving Q2 rankings in key categories such as Genetics and Molecular Medicine in 2023. Not only does Frontiers in Genetics contribute to the scholarly dialogue by publishing impactful studies, but it also promotes accessibility to vital research, ensuring that knowledge is available to a global audience. This journal is a vital resource for researchers, professionals, and students looking to stay at the forefront of genetic discoveries and their applications, reflective of its engagement with contemporary challenges in genetics and healthcare.

Genes

Connecting researchers to shape the future of genetics.
Publisher: MDPIISSN: Frequency: 12 issues/year

Genes is a leading open-access journal published by MDPI that focuses on advancing the field of genetics and genomics. Established in 2010 and based in Basel, Switzerland, this journal has made significant strides in promoting innovative research in both clinical genetics and molecular biology. With an impact factor reflecting its relevance and quality, Genes has been classified in the Q2 quartile for Genetics and the Q3 quartile for clinical Genetics as of 2023. The journal provides an accessible platform for researchers, professionals, and students to disseminate their findings and explore emerging trends across the genetics landscape. Accessible online since its inception, Genes allows for continuous engagement and collaboration within the scientific community, fostering a deeper understanding of genetic mechanisms and their implications in health and disease.

BIOCHEMICAL GENETICS

Connecting Biochemistry and Genetics for a Sustainable Future
Publisher: SPRINGER/PLENUM PUBLISHERSISSN: 0006-2928Frequency: 6 issues/year

BIOCHEMICAL GENETICS, published by Springer/Plenum Publishers, is a prominent journal in the fields of biochemistry, genetics, and molecular biology, with a substantial impact on the scientific community since its inception in 1967. The journal holds a significant position within various academic quartiles, ranking Q2 in Ecology, Evolution, Behavior and Systematics, and Q3 in Biochemistry, Genetics, and Medicine (miscellaneous), among others, demonstrating its diverse and interdisciplinary reach. With an ISSN of 0006-2928 and an E-ISSN of 1573-4927, it is recognized for contributing critical research insights and methodologies that drive the fields of biochemical genetics forward. Although it is not an Open Access journal, it provides vital access options and resources for researchers globally, facilitating the dissemination of knowledge across institutions. Positioned within the competitive landscape of Scopus rankings, it maintains respectable standings across its focused areas, making it an invaluable resource for researchers, professionals, and students seeking to deepen their understanding of genetic mechanisms and biochemical processes.

npj Genomic Medicine

Unlocking the Potential of Genomic Research
Publisher: NATURE PORTFOLIOISSN: Frequency: 1 issue/year

npj Genomic Medicine is a leading open-access journal published by NATURE PORTFOLIO, specializing in the rapidly evolving areas of genomic medicine, including genetics, molecular biology, and clinical applications. Launched in 2016, the journal has quickly established itself within the academic community, boasting a prestigious Q1 ranking in multiple categories, including Genetics and Molecular Biology, with remarkable positions in both Scopus ranks and percentiles. With an emphasis on innovative genomic research that bridges the gap between laboratory findings and clinical implementation, npj Genomic Medicine aims to provide a platform for researchers, professionals, and students to share significant advancements and insights. Being an open-access journal enhances accessibility to cutting-edge research, ensuring that vital discoveries in genomics can benefit a global audience and facilitate interdisciplinary collaboration. The journal continues to contribute to the forefront of genomic research, impacting both academic scholarship and practical healthcare solutions.