PROTEIN SCIENCE

Scope & Guideline

Exploring the Vital Role of Proteins in Health and Disease

Introduction

Welcome to your portal for understanding PROTEIN SCIENCE, featuring guidelines for its aims and scope. Our guidelines cover trending and emerging topics, identifying the forefront of research. Additionally, we track declining topics, offering insights into areas experiencing reduced scholarly attention. Key highlights include highly cited topics and recently published papers, curated within these guidelines to assist you in navigating influential academic dialogues.
LanguageEnglish
ISSN0961-8368
PublisherWILEY
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 1992 to 2024
AbbreviationPROTEIN SCI / Protein Sci.
Frequency12 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address111 RIVER ST, HOBOKEN 07030-5774, NJ

Aims and Scopes

The journal 'Protein Science' primarily focuses on advancing the understanding of protein structure, function, and dynamics through innovative research methodologies and interdisciplinary approaches. Its aim is to provide a platform for the dissemination of high-quality research that contributes to the field of protein science, including but not limited to structural biology, biochemistry, and molecular biology.
  1. Protein Structure and Dynamics:
    Research dedicated to elucidating the three-dimensional structures of proteins and their dynamics in various environments, often using techniques like X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy.
  2. Protein Engineering and Design:
    Innovative methods in designing and engineering proteins for specific functions, including the development of novel enzymes, therapeutic proteins, and biosensors.
  3. Protein-Protein Interactions:
    Studies focusing on the interactions between proteins, including binding mechanisms, allosteric regulation, and the impact of post-translational modifications on these interactions.
  4. Proteomics and Functional Studies:
    Comprehensive explorations of protein expression profiles, modifications, and interactions within biological systems, often utilizing mass spectrometry and bioinformatics.
  5. Disease Mechanisms and Therapeutic Targets:
    Research elucidating the role of proteins in diseases, including neurodegenerative conditions and cancer, and the identification of potential therapeutic targets.
  6. Computational Biology and Modeling:
    Use of computational methods, including machine learning and molecular dynamics simulations, to predict protein structures, interactions, and dynamics.
  7. Phase Separation and Biomolecular Condensates:
    Investigating the role of protein phase separation in cellular processes and the formation of membraneless organelles.
The journal has embraced several emerging themes that reflect the current trends in protein science. These trends indicate a shift towards more integrative approaches that consider protein dynamics, interactions, and the influence of cellular environments.
  1. Protein Phase Separation:
    There is a significant increase in research exploring the phenomenon of liquid-liquid phase separation of proteins and its implications for cellular organization and function.
  2. Machine Learning in Protein Science:
    The integration of machine learning techniques for predicting protein structure, dynamics, and function is on the rise, showcasing the intersection of computational methods with experimental biology.
  3. Post-Translational Modifications:
    Investigation into the effects of post-translational modifications on protein function and stability is trending, reflecting an increased interest in how these modifications influence disease mechanisms.
  4. Therapeutic Protein Engineering:
    Emerging research is focusing on the design and engineering of therapeutic proteins, including novel biologics and biosensors, driven by the need for innovative treatment strategies.
  5. Interdisciplinary Approaches:
    There is a growing trend towards interdisciplinary research that combines structural biology, biochemistry, and computational techniques to address complex biological questions.
  6. SARS-CoV-2 Research:
    Research related to SARS-CoV-2, including protein interactions and therapeutic targeting, has surged, reflecting the global health crisis and the urgency of developing effective treatments.

Declining or Waning

While the journal continues to thrive in many areas, certain themes have shown a decline in focus over recent years. This could reflect shifts in research priorities, the emergence of new methodologies, or the completion of previously active research topics.
  1. Traditional Biochemical Assays:
    There appears to be a waning interest in traditional biochemical assays, as researchers increasingly turn to high-throughput and computational methods for studying protein interactions and functions.
  2. Static Structural Studies:
    The emphasis on static structural studies, while still relevant, has diminished compared to dynamic studies that explore protein flexibility and interactions in real-time.
  3. Single-Domain Antibody Research:
    Research focused on single-domain antibodies has seen a decrease, possibly due to the saturation of findings in this area and the growing interest in bispecific and multifunctional antibodies.

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