TOXICOLOGIC PATHOLOGY

Scope & Guideline

Exploring the Complex Interactions of Toxicology and Pathology

Introduction

Welcome to the TOXICOLOGIC PATHOLOGY information hub, where our guidelines provide a wealth of knowledge about the journal’s focus and academic contributions. This page includes an extensive look at the aims and scope of TOXICOLOGIC PATHOLOGY, highlighting trending and emerging areas of study. We also examine declining topics to offer insight into academic interest shifts. Our curated list of highly cited topics and recent publications is part of our effort to guide scholars, using these guidelines to stay ahead in their research endeavors.
LanguageEnglish
ISSN0192-6233
PublisherSAGE PUBLICATIONS INC
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 1972 to 2024
AbbreviationTOXICOL PATHOL / Toxicol. Pathol.
Frequency8 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address2455 TELLER RD, THOUSAND OAKS, CA 91320

Aims and Scopes

The journal 'Toxicologic Pathology' focuses on the intersection of toxicology and pathology, providing a platform for research that elucidates the effects of chemicals and pharmaceuticals on biological systems. It aims to advance the understanding of toxicological mechanisms through histopathological evaluations and innovative methodologies.
  1. Toxicological Mechanisms and Pathology:
    Research exploring the cellular and molecular mechanisms by which toxic substances induce pathological changes in various organ systems, including liver, kidney, and lung.
  2. Histopathological Assessments:
    Emphasis on the development and application of histopathological techniques to evaluate the effects of toxicants in animal models, contributing to the understanding of disease processes.
  3. Preclinical Toxicity Studies:
    Focus on the assessment of safety and efficacy of new drugs and chemicals through rigorous preclinical studies, including the use of animal models to predict human responses.
  4. Novel Methodologies in Toxicology:
    Incorporation of advanced technologies such as gene expression analysis, organoid models, and machine learning techniques to enhance the evaluation of toxicological effects.
  5. Contributions to Regulatory Toxicology:
    Providing insights and data that aid in the regulatory approval process for pharmaceuticals and chemicals, focusing on the implications for human health.
In recent years, 'Toxicologic Pathology' has seen a rise in the exploration of innovative themes and methodologies that reflect current trends in toxicological research. These emerging scopes highlight the journal's adaptability and commitment to addressing contemporary challenges in the field.
  1. Organoid and 3D Culture Models:
    There is a growing interest in utilizing organoid models and three-dimensional cultures for toxicological assessments, allowing for more physiologically relevant evaluations of drug and chemical effects.
  2. Machine Learning and AI in Toxicology:
    The application of artificial intelligence and machine learning techniques for analyzing toxicological data is trending, enhancing the ability to predict outcomes and streamline assessments.
  3. Biomarkers of Toxicity:
    Research focusing on identifying and validating biomarkers for early detection of toxicity is on the rise, providing critical insights for predictive toxicology.
  4. Integrated Approaches to Risk Assessment:
    Emerging studies are increasingly adopting integrated approaches that combine histopathological, biochemical, and behavioral evaluations to assess the overall impact of toxicants.
  5. Focus on Environmental Toxicology:
    There is an increasing emphasis on the effects of environmental toxicants and pollutants on health, reflecting a broader concern for ecological impacts and public health.

Declining or Waning

While 'Toxicologic Pathology' maintains a robust focus on various aspects of toxicological research, certain themes have shown a decline in prominence over recent publications. These waning scopes may reflect shifts in research interests or advancements in methodologies that have rendered previous approaches less relevant.
  1. Traditional Toxicity Testing Models:
    There is a noticeable reduction in studies relying solely on traditional animal models for toxicity testing, as newer methodologies and in vitro models gain traction.
  2. Single-Factor Toxicological Studies:
    Research focusing on the effects of single toxicants in isolation is becoming less frequent, with a trend towards more complex studies that consider multi-factorial interactions.
  3. Basic Histopathological Techniques:
    The reliance on basic histopathological examinations without incorporating advanced imaging or molecular techniques is decreasing, as the field moves towards more integrative approaches.
  4. Carcinogenicity Studies in Long-Term Models:
    The traditional long-term carcinogenicity studies in laboratory animals are becoming less common, as shorter, more predictive models and alternative methods are being developed.
  5. Generalized Toxicity Assessments:
    Research that provides broad, non-specific toxicity assessments is waning in favor of studies that focus on specific mechanisms or pathways affected by toxicants.

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