TOXICOLOGY
Scope & Guideline
Elevating research in toxicology to safeguard public health.
Introduction
Aims and Scopes
- Ecotoxicology and Environmental Toxicology:
Research on the effects of pollutants such as heavy metals, pesticides, and pharmaceuticals on aquatic and terrestrial organisms, including studies on bioaccumulation, biomagnification, and ecological risk assessments. - Mechanisms of Toxicity:
Investigations into the biochemical and physiological mechanisms through which toxic substances affect organisms, including studies on oxidative stress, hormonal disruption, and genetic damage. - Toxicological Assessment and Risk Evaluation:
Development and application of methodologies for assessing the toxicity of chemicals, including single and combined exposures, chronic and acute toxicity tests, and modeling of ecological impacts. - Biomarkers and Bioindicators:
Utilization of various biological indicators to assess the health of ecosystems and the impact of contaminants, including studies on gene expression, enzyme activity, and physiological responses. - Nanotoxicology:
Research focused on the toxicity of nanoparticles and their interactions with biological systems, including studies on environmental persistence and impacts on microbial and animal health. - Phytotoxicity and Soil Toxicology:
Studies examining the effects of contaminants on plant growth and soil health, including the impact of agricultural chemicals on soil microbial communities and plant physiology.
Trending and Emerging
- Microplastics and Their Ecotoxicological Effects:
An increasing number of studies are focusing on the impacts of microplastics on aquatic and terrestrial organisms, highlighting the urgent need to understand their environmental fate and biological effects. - Pharmaceuticals and Personal Care Products (PPCPs):
Research into the ecotoxicological impacts of pharmaceuticals and their mixtures is on the rise, driven by concerns over their presence in water bodies and effects on non-target organisms. - Combined Chemical Exposures and Mixtures:
There is a growing emphasis on studying the combined effects of multiple chemicals, reflecting real-world exposure scenarios more accurately and addressing the complexity of environmental toxicity. - Endocrine Disruption and Hormonal Toxicology:
An emerging focus on the effects of endocrine-disrupting chemicals (EDCs) and their mechanisms of action is evident, emphasizing the need for understanding how these substances affect reproductive and developmental health. - Climate Change and Toxicology:
Research exploring the interactions between climate change factors (such as temperature and salinity) and chemical toxicity is gaining traction, indicating a holistic approach to understanding ecological impacts.
Declining or Waning
- Traditional Chemical Toxicology:
Research specifically focused on the toxicity of traditional chemicals (e.g., organophosphates) appears to be declining, possibly due to a shift towards investigating mixtures and real-world exposure scenarios. - Aquatic Toxicity of Legacy Pollutants:
There seems to be a waning interest in studies solely focused on the aquatic toxicity of legacy pollutants, such as PCBs and PAHs, as newer contaminants of emerging concern gain more attention. - Laboratory-Based Toxicity Testing:
A decrease in emphasis on standard laboratory toxicity testing methods may be noted, as the field moves towards more ecologically relevant assessments that consider environmental complexities. - Biodiversity Studies in Toxicology:
Research explicitly linking biodiversity metrics to toxicological outcomes appears less frequent, possibly overshadowed by more direct assessments of chemical impacts on specific species or ecosystems.
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