BIOORGANIC & MEDICINAL CHEMISTRY
Scope & Guideline
Transforming Therapeutics with Cutting-Edge Chemistry
Introduction
Aims and Scopes
- Medicinal Chemistry:
Research devoted to the design and synthesis of new pharmaceutical agents, exploring their mechanisms of action and therapeutic potential. - Bioorganic Chemistry:
Studies on the chemical processes within and related to living organisms, including the synthesis of biomolecules and their interactions. - Pharmacology and Drug Development:
Investigations into the pharmacokinetics, pharmacodynamics, and therapeutic efficacy of newly developed compounds in various disease models. - Chemical Biology:
Research that bridges chemistry and biology, focusing on the development of chemical tools to study biological systems. - Natural Products Chemistry:
Exploration and modification of natural products to develop new therapeutic agents, including their structure-activity relationships. - Bioconjugation and Drug Delivery Systems:
Innovative strategies for enhancing drug delivery and targeting, including the use of conjugates and prodrugs.
Trending and Emerging
- PROTACs and Targeted Protein Degradation:
The increasing interest in PROTACs (Proteolysis Targeting Chimeras) highlights a shift towards innovative strategies for targeted protein degradation, offering new avenues for therapeutic intervention. - Immuno-oncology and Cancer Immunotherapy:
Research on compounds that modulate immune responses to enhance anti-tumor activity is gaining momentum, reflecting the growing importance of immunotherapy in cancer treatment. - RNA-targeted Therapeutics:
With advancements in RNA biology, there is a rising focus on developing small molecules that target RNA structures, potentially leading to novel therapeutic agents. - Nanotechnology in Drug Delivery:
The integration of nanotechnology for drug delivery systems is increasingly prominent, focusing on improving bioavailability and targeting specific tissues. - Natural Product Derivatives:
There is renewed interest in modifying natural products to enhance their therapeutic properties, leveraging their complex structures and biological activity. - Synthetic Biology Applications:
Emerging research is increasingly focusing on the application of synthetic biology techniques for drug discovery and development, showcasing the interdisciplinary nature of modern medicinal chemistry.
Declining or Waning
- Traditional Antibiotic Development:
Research in this area has decreased as focus shifts toward novel mechanisms of action and alternative therapeutic strategies to combat antibiotic resistance. - Basic Organic Synthesis:
Publications solely focused on the synthetic methodologies without direct application to biological systems are becoming less frequent as interdisciplinary approaches gain traction. - Single-target Drug Discovery:
The trend is moving towards multi-target approaches or combination therapies, leading to a reduction in publications centered on single-target compounds. - In Vitro Studies without In Vivo Correlation:
There is a waning interest in studies that do not extend beyond in vitro evaluations, as there is a growing emphasis on translational research that includes in vivo studies.
Similar Journals
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JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
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Medicinal Chemistry
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PHARMACEUTICAL CHEMISTRY JOURNAL
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Open Chemistry
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EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Pioneering Insights for the Future of Pharmacology.European Journal of Medicinal Chemistry, a premier publication by Elsevier France-Editions Scientifiques Médicales Elsevier, has been at the forefront of advancing medicinal chemistry since its inception in 1974. With an impressive impact factor and ranking in the Q1 quartile across multiple categories including Drug Discovery, Medicine (miscellaneous), Organic Chemistry, and Pharmacology, this journal delivers cutting-edge research and reviews that are vital for researchers and professionals in the field. The journal’s scope encompasses the design, synthesis, and evaluation of biological activity of bioactive compounds, making it a critical resource for those looking to innovate in drug development and therapeutic strategies. Although currently not open access, subscribers can benefit from its diverse range of high-quality articles, ensuring the dissemination of knowledge in the ever-evolving landscape of medicinal chemistry. The European Journal of Medicinal Chemistry continues to play a pivotal role in shaping the future of pharmacological research and its application, thus appealing to an audience dedicated to making impactful scientific contributions.
RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY
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CURRENT TOPICS IN MEDICINAL CHEMISTRY
Exploring Breakthroughs in Therapeutic StrategiesCURRENT TOPICS IN MEDICINAL CHEMISTRY is a prestigious journal published by Bentham Science Publishers Ltd, dedicated to advancing the field of medicinal chemistry through the dissemination of high-quality research from 2001 to 2024. With an ISSN of 1568-0266 and an E-ISSN of 1873-4294, this journal is recognized for its significant contributions, as evidenced by its Scopus ranking in the 63rd percentile in the category of Drug Discovery, specifically at position #58 out of 157. Currently placed in Quartile 3 within Drug Discovery and Quartile 2 in miscellaneous medicine as of 2023, it serves as an essential resource for researchers, professionals, and students interested in the latest developments, methodologies, and applications in medicinal chemistry. The journal aims to foster collaboration and innovation by featuring original research articles, reviews, and brief communications that address current and emerging challenges in the discipline. Although it is not an open access platform, the journal's rich content is indispensable for those striving to enhance therapeutic strategies and drug development processes.