Annual Review of Cell and Developmental Biology
Scope & Guideline
Synthesizing Knowledge to Propel Biological Innovation
Introduction
Aims and Scopes
- Cellular Mechanisms and Signaling:
Research in this area explores the fundamental processes that govern cell behavior, including signaling pathways, gene regulation, and cellular responses to environmental changes. - Developmental Biology and Morphogenesis:
This scope encompasses studies on how organisms develop from a single cell to complex structures, focusing on tissue morphogenesis, organ development, and the interplay between cells and their microenvironment. - Regenerative Biology and Repair Mechanisms:
The journal highlights advancements in understanding regeneration and repair processes in various organisms, including mechanisms of fibrosis and tissue homeostasis. - Model Organisms and Comparative Biology:
Utilizing diverse model systems such as zebrafish, flies, and plants, research often compares cellular and developmental mechanisms across species, shedding light on evolutionary biology. - Technological Advances in Imaging and Analysis:
The journal incorporates studies utilizing cutting-edge imaging techniques and quantitative analyses to explore cellular dynamics and interactions in vivo.
Trending and Emerging
- Single-Cell Analysis and Transcriptomics:
There is a marked increase in research focused on single-cell methodologies, particularly the dynamics of mRNA life cycles and expression profiling, highlighting the importance of cellular heterogeneity. - Mechanobiology and Physical Forces in Development:
Emerging studies emphasize the role of mechanical forces in shaping cellular and tissue behavior, reflecting a growing recognition of the physical context in biological processes. - Intercellular Communication and Extracellular Vesicles:
Research on how cells communicate through extracellular vesicles and signaling molecules is trending, particularly in the context of health and disease, underscoring the relevance of these processes in regenerative medicine. - Neurodevelopment and Neuroimmunology:
An increasing number of studies are focusing on the intersection of neurodevelopment and immune responses, indicating a trend towards understanding how these systems interact during tissue homeostasis and repair. - Organoids and Tissue Engineering:
Advancements in organoid technology and tissue engineering are becoming a significant focus, reflecting the potential for these systems in modeling development and disease.
Declining or Waning
- Classical Cell Biology Techniques:
While foundational techniques in cell biology remain important, there is a noticeable shift towards more advanced methodologies, leading to a decline in publications focused solely on traditional experimental approaches. - Basic Mechanisms of Cell Cycle Regulation:
Research specifically centered on the cell cycle has become less prominent, possibly due to the increasing integration of cell cycle studies with broader developmental and signaling context. - Studies Lacking Multidisciplinary Approaches:
Papers that do not incorporate interdisciplinary perspectives, such as integrating genomics, bioinformatics, and system biology with traditional cell biology, are witnessing a decline in interest and publication opportunities.
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