BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Scope & Guideline

Illuminating the Pathways of Molecular Medicine

Introduction

Welcome to the BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE information hub, where our guidelines provide a wealth of knowledge about the journal’s focus and academic contributions. This page includes an extensive look at the aims and scope of BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, highlighting trending and emerging areas of study. We also examine declining topics to offer insight into academic interest shifts. Our curated list of highly cited topics and recent publications is part of our effort to guide scholars, using these guidelines to stay ahead in their research endeavors.
LanguageDutch
ISSN0925-4439
PublisherELSEVIER
Support Open AccessNo
CountryNetherlands
TypeJournal
Convergefrom 1990 to 2025
AbbreviationBBA-MOL BASIS DIS / Biochim. Biophys. Acta-Mol. Basis Dis.
Frequency12 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
AddressRADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS

Aims and Scopes

The journal "Biochimica et Biophysica Acta - Molecular Basis of Disease" focuses on the molecular mechanisms underlying various diseases, emphasizing cellular and molecular biology approaches. The journal aims to disseminate impactful research that sheds light on disease pathogenesis, potential therapeutic targets, and innovative treatment strategies.
  1. Molecular Mechanisms of Disease:
    The journal emphasizes research elucidating the molecular and cellular mechanisms underlying various diseases, including cancer, neurodegenerative disorders, and metabolic diseases.
  2. Translational Research:
    It focuses on studies that bridge basic research and clinical applications, aiming to translate laboratory findings into potential therapeutic strategies.
  3. Cellular and Molecular Biology Techniques:
    The journal publishes articles utilizing diverse experimental approaches, including genomics, proteomics, metabolomics, and advanced imaging techniques to explore disease mechanisms.
  4. Therapeutic Strategies:
    Research on novel therapeutic interventions, including drug development, gene therapy, and immunotherapy, is a core focus, highlighting innovative approaches to combat diseases.
  5. Interdisciplinary Research:
    The journal encourages interdisciplinary studies that integrate insights from biochemistry, molecular biology, immunology, and genetics to provide a comprehensive understanding of disease processes.
The journal has exhibited a dynamic evolution in its focus areas, with certain themes gaining prominence in recent years. These emerging scopes reflect advancements in technology, evolving scientific inquiries, and the pressing need for innovative treatment strategies.
  1. Microbiome and Disease:
    Research investigating the role of the microbiome in disease development and progression is on the rise, highlighting the complex interactions between gut health and systemic diseases.
  2. Immunotherapy and Immune Modulation:
    There is an increasing focus on immunotherapy, particularly in cancer treatment, as studies explore the mechanisms of immune evasion and strategies to enhance anti-tumor immune responses.
  3. Metabolic Reprogramming in Disease:
    Emerging studies are emphasizing the role of metabolic reprogramming in cancer and other diseases, exploring how altered metabolism contributes to disease pathogenesis and therapy resistance.
  4. Autophagy and Cellular Homeostasis:
    Research on autophagy is gaining traction, particularly its role in cellular homeostasis, immune response, and neurodegeneration, reflecting its potential as a therapeutic target.
  5. Personalized Medicine and Genomics:
    There is a growing trend towards personalized medicine, with studies focusing on genomic alterations and their implications for tailored therapeutic approaches in various diseases.

Declining or Waning

While certain themes remain prominent, some areas of research have shown a decline in publication frequency. This may reflect shifting interests within the scientific community or advancements in technology that render previous topics less relevant.
  1. Traditional Pharmacology:
    Research focusing solely on traditional pharmacological approaches is declining, as there is a growing interest in personalized medicine and targeted therapies that consider individual genetic and molecular profiles.
  2. Basic Biochemical Studies:
    While foundational biochemical studies are essential, there is a waning emphasis on purely descriptive biochemical research without clear implications for disease mechanisms or therapeutic strategies.
  3. Animal Models of Disease:
    The reliance on conventional animal models is decreasing, with a shift towards more complex models, including organoids and humanized systems, that better mimic human disease conditions.
  4. Static In Vitro Studies:
    There is a noticeable decline in studies that do not incorporate dynamic or three-dimensional culture systems, as the scientific community increasingly recognizes the limitations of 2D cell cultures in reflecting in vivo conditions.

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