Cell Division
Scope & Guideline
Exploring the intricacies of cellular mechanisms.
Introduction
Aims and Scopes
- Cell Cycle Regulation:
Research in this area focuses on the molecular mechanisms that govern the cell cycle, including checkpoints, mitotic kinases, and the role of centrosomes. - Cancer Biology and Therapeutics:
The journal publishes studies on the mechanisms of cancer progression, including the roles of specific genes, signaling pathways, and potential therapeutic targets. - Non-Coding RNAs in Cell Dynamics:
There is a significant focus on the roles of long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) in regulating cell proliferation, apoptosis, and cancer progression. - Molecular Mechanisms of Cell Death:
Exploration of various forms of cell death, including apoptosis, pyroptosis, and ferroptosis, and their implications in disease and therapy. - Stem Cell Biology and Differentiation:
Research on the role of stem cells in cancer and tissue regeneration, including mechanisms of stemness and differentiation pathways.
Trending and Emerging
- Role of Non-Coding RNAs in Cancer:
Recent publications underscore the increasing importance of non-coding RNAs, such as miRNAs and lncRNAs, in regulating cancer cell behavior, indicating a shift towards understanding their therapeutic potential. - Ferroptosis and Pyroptosis:
There is a growing focus on these novel forms of regulated cell death, particularly in the context of cancer therapy and resistance, suggesting their relevance in future treatment strategies. - Therapeutic Targeting of Mitotic Kinases:
Emerging research highlights mitotic kinases as promising targets for cancer therapy, reflecting a trend towards developing precise treatments that disrupt cancer cell division. - Cancer Stem Cells and Tumor Microenvironment:
Studies increasingly explore the interactions between cancer stem cells and their microenvironment, indicating a trend towards understanding cancer heterogeneity and therapy resistance. - Integrative Approaches in Cancer Research:
The integration of omics technologies (genomics, proteomics) with cell biology is becoming prevalent, facilitating a more comprehensive understanding of cancer mechanisms and potential therapeutic targets.
Declining or Waning
- Traditional Cell Culture Techniques:
There is a noticeable decrease in studies employing basic in vitro cell culture methods, as researchers increasingly adopt more complex and relevant models, such as 3D cultures or organoids. - Basic Mechanisms of Cell Division:
While foundational studies on cell division mechanisms are still relevant, there seems to be a waning interest in purely descriptive studies without novel insights into therapeutic applications or disease implications. - In Vivo Animal Models:
Research utilizing traditional in vivo models to study cell division and cancer has seen a decline, likely due to the rising interest in more sophisticated and human-relevant models.
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