CLINICAL & EXPERIMENTAL METASTASIS

Scope & Guideline

Elevating the Science of Metastasis

Introduction

Welcome to your portal for understanding CLINICAL & EXPERIMENTAL METASTASIS, featuring guidelines for its aims and scope. Our guidelines cover trending and emerging topics, identifying the forefront of research. Additionally, we track declining topics, offering insights into areas experiencing reduced scholarly attention. Key highlights include highly cited topics and recently published papers, curated within these guidelines to assist you in navigating influential academic dialogues.
LanguageEnglish
ISSN0262-0898
PublisherSPRINGER
Support Open AccessNo
CountryNetherlands
TypeJournal
Convergefrom 1983 to 2024
AbbreviationCLIN EXP METASTAS / Clin. Exp. Metastasis
Frequency6 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
AddressVAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS

Aims and Scopes

The journal 'Clinical & Experimental Metastasis' focuses on the multifaceted aspects of cancer metastasis, exploring both clinical and experimental dimensions. It aims to provide a comprehensive platform for research that enhances the understanding of metastatic processes, therapeutic interventions, and innovative treatment strategies.
  1. Metastatic Mechanisms and Biology:
    Research into the biological underpinnings of metastasis, including cellular and molecular mechanisms that facilitate cancer spread. This includes studies on epithelial-mesenchymal transition (EMT), genetic alterations, and tumor microenvironment interactions.
  2. Therapeutic Strategies and Innovations:
    Exploration of novel therapeutic approaches aimed at preventing or treating metastasis, such as targeted therapies, immunotherapies, and combination treatments. This encompasses clinical trials and preclinical studies.
  3. Diagnostic Techniques and Biomarkers:
    Development and evaluation of diagnostic tools and biomarkers for early detection of metastasis, including imaging techniques, circulating tumor cells (CTCs), and liquid biopsies.
  4. Clinical Outcomes and Patient Management:
    Investigation of clinical outcomes related to metastatic cancer, including treatment responses, prognostic factors, and patient quality of life. This also includes analyses of treatment regimens and their efficacy.
  5. Translational Research and Preclinical Models:
    Utilization of translational research approaches and preclinical models to bridge laboratory findings with clinical applications, thereby enhancing the understanding of metastasis in a real-world context.
The journal has seen a rise in several innovative and impactful research themes that reflect the current landscape of cancer metastasis research. These emerging areas highlight the ongoing evolution of therapeutic strategies and diagnostic advancements.
  1. Immunotherapy and Immune Checkpoint Inhibition:
    There is a significant increase in studies exploring the role of immunotherapy and immune checkpoint inhibitors in treating metastatic cancers, reflecting a broader trend in oncology toward harnessing the immune system.
  2. Liquid Biopsy and Circulating Tumor Cells (CTCs):
    Research focusing on liquid biopsies and CTCs has gained momentum, emphasizing their potential for non-invasive monitoring of metastatic disease and treatment response.
  3. Targeted Therapies and Personalized Medicine:
    A notable trend is the exploration of targeted therapies that are tailored to the specific genetic and molecular profiles of tumors, which has become increasingly important in the management of metastatic cancers.
  4. Tumor Microenvironment and Metastatic Niche:
    The investigation of the tumor microenvironment and its influence on metastatic behavior is emerging as a critical area of research, highlighting the complex interactions that drive metastasis.
  5. Preclinical Models and Translational Research:
    There is a growing emphasis on the use of advanced preclinical models and translational research to better predict clinical outcomes and improve therapeutic strategies against metastasis.

Declining or Waning

While the journal covers a wide array of topics related to cancer metastasis, some areas have seen a decline in focus over recent years. This may reflect shifts in research priorities or advancements in other methodologies.
  1. Basic Research on Non-Metastatic Tumor Biology:
    There appears to be a waning interest in research focused solely on the biology of primary tumors without a direct connection to metastatic processes, as the field shifts toward understanding the complexities of metastasis.
  2. Conventional Chemotherapy Approaches:
    Studies centered on traditional chemotherapy regimens for metastatic cancer are less frequent, as there is a growing emphasis on personalized medicine and targeted therapies that offer more tailored treatment options.
  3. Single-Agent Therapies:
    Research dedicated to single-agent therapies is declining, as current trends favor combination therapies that leverage synergistic effects to combat metastasis more effectively.
  4. Descriptive Studies without Translational Insight:
    There has been a noticeable decrease in purely descriptive studies that do not provide translational insights or therapeutic implications, indicating a shift towards research that directly informs clinical practice.

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