Molecular & Cellular Oncology
Scope & Guideline
Advancing cancer research through molecular insights.
Introduction
Aims and Scopes
- Molecular Mechanisms of Cancer:
The journal investigates the fundamental molecular pathways involved in cancer initiation, progression, and metastasis, including signaling pathways, genetic mutations, and epigenetic modifications. - Therapeutic Development and Targeting:
Research focuses on developing novel therapeutic strategies, including small molecules, biologics, and immunotherapies, aimed at specific molecular targets identified in cancer cells. - Biomarkers and Precision Medicine:
The journal emphasizes the identification and validation of biomarkers for cancer diagnosis, prognosis, and treatment response, contributing to the advancement of personalized medicine in oncology. - Cancer Microenvironment and Metabolism:
Studies explore the role of the tumor microenvironment in cancer biology, including interactions between cancer cells and stromal components, as well as metabolic adaptations that support tumor growth. - Innovative Research Methodologies:
The journal employs advanced research methodologies, including bioinformatics, proteomics, and genomic studies, to uncover new insights into cancer biology and treatment.
Trending and Emerging
- Targeting the Tumor Microenvironment:
There is an increasing emphasis on understanding and targeting the tumor microenvironment, including immune cell interactions and stromal contributions to cancer progression and therapy resistance. - Autophagy and Cancer Metabolism:
Research on the role of autophagy in cancer cell survival and metabolism is gaining prominence, reflecting a deeper understanding of metabolic vulnerabilities in cancer cells. - RNA and Epigenetic Regulation:
Emerging studies are focusing on the roles of non-coding RNAs and epigenetic modifications in cancer biology, revealing their potential as therapeutic targets and biomarkers. - Immunotherapy and Immune Checkpoints:
With the rise of immunotherapy in cancer treatment, there is a growing body of research aimed at understanding and improving the efficacy of immune checkpoint inhibitors. - Genome Editing and CRISPR Technologies:
Recent publications indicate a trend towards utilizing genome editing technologies, such as CRISPR, to identify novel therapeutic targets and understand cancer biology.
Declining or Waning
- Traditional Chemotherapy Mechanisms:
Papers focusing solely on traditional chemotherapy mechanisms have decreased, suggesting a shift towards exploring more targeted and personalized treatment approaches. - Basic Cell Culture Studies:
Research primarily based on basic cell culture models without integration of in vivo or clinical relevance appears to be declining, as there is a stronger emphasis on studies that incorporate more complex biological models. - General Cancer Epidemiology:
Themes related to broad epidemiological studies of cancer incidence and prevalence have waned, with a move towards more mechanistic and targeted research that directly informs therapeutic strategies.
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