Computational Toxicology
Scope & Guideline
Empowering insights at the intersection of toxicology and technology.
Introduction
Aims and Scopes
- Quantitative Structure-Activity Relationship (QSAR) Modeling:
Utilizing mathematical and statistical techniques to predict the toxicity of chemical compounds based on their molecular structure, enabling risk assessment without extensive animal testing. - Adverse Outcome Pathways (AOPs):
Developing frameworks that describe the relationship between chemical exposure and adverse health effects, facilitating the understanding of mechanisms of toxicity. - Physiologically-Based Kinetic (PBK) Modeling:
Creating models that simulate the absorption, distribution, metabolism, and excretion (ADME) of chemicals in biological systems, aiding in the prediction of human and environmental exposure. - Machine Learning and Artificial Intelligence Applications:
Employing advanced computational techniques to enhance predictive accuracy in toxicology, including the classification of toxic effects and the identification of potential chemical hazards. - Nanotoxicology and Environmental Toxicology:
Investigating the toxicological implications of nanomaterials and environmental chemicals, focusing on their interactions with biological systems. - Chemical Safety Assessment and Regulatory Frameworks:
Supporting the integration of computational approaches into regulatory practices to ensure the safe use of chemicals in various industries.
Trending and Emerging
- Integration of Big Data and High-Throughput Screening:
The use of large datasets combined with high-throughput screening technologies is on the rise, enabling more comprehensive analyses of chemical toxicity and enhancing predictive models. - Development of New Approach Methodologies (NAMs):
There is a growing emphasis on NAMs, which utilize innovative in silico and in vitro methodologies to enhance the safety assessment process and reduce reliance on animal testing. - Focus on Environmental and Human Health Risk Assessment:
Emerging themes include the assessment of environmental chemicals and their impact on human health, especially in light of increased regulatory scrutiny. - Personalized Toxicology and Risk Assessment:
The incorporation of genetic and biological variability in toxicity assessments is becoming more prevalent, facilitating personalized approaches to toxicological risk management. - Advancements in Computational Methods for Mixture Toxicology:
Research is increasingly addressing the complexities of chemical mixtures and their combined effects, reflecting a more holistic approach to toxicology.
Declining or Waning
- Traditional In Vivo Toxicology Studies:
There is a noticeable reduction in reliance on traditional animal testing methods as computational approaches gain traction, reflecting a broader acceptance of in silico predictions. - Basic Toxicity Screening Methods:
Basic screening methods that do not leverage advanced computational techniques are becoming less prominent, as more sophisticated models provide better predictive capabilities. - Single Endpoint Toxicity Assessments:
The shift towards integrated approaches that consider multiple endpoints and mechanisms of action has led to a decline in the publication of studies focused solely on single toxicity endpoints.
Similar Journals
TOXICOLOGY IN VITRO
Pioneering Innovative Toxicology ResearchTOXICOLOGY IN VITRO is a premier journal published by PERGAMON-ELSEVIER SCIENCE LTD, focusing on the latest advancements in the field of toxicology, particularly through in vitro methodologies. With an ISSN of 0887-2333 and an E-ISSN of 1879-3177, this journal serves as a critical platform for researchers aiming to disseminate their findings in toxicology, emphasizing innovative approaches and applications in pharmacology and toxicology. Featuring a commendable impact factor and classified in the second quartile (Q2) for both Medicine (miscellaneous) and Toxicology in 2023, the journal holds a significant position within the academic community, ranking 41st out of 133 in the Toxicology category according to Scopus, representing the 69th percentile. Despite being a subscription-based publication, it continuously attracts submissions from leading scientists worldwide, fostering a vibrant exchange of scientific knowledge. Since its inception in 1987, TOXICOLOGY IN VITRO has consistently aimed to enhance understanding of toxicological challenges, making it an invaluable resource for professionals, students, and researchers dedicated to developing safer pharmaceuticals and understanding the biological pathways influenced by potential toxic agents.
ARCHIVES OF TOXICOLOGY
Uncovering Insights, Shaping SafetyARCHIVES OF TOXICOLOGY is a prestigious journal published by Springer Heidelberg, dedicated to advancing research in the field of toxicology and related disciplines. With a distinguished history dating back to 1930, this journal has continuously provided vital insights and groundbreaking studies, making it a cornerstone in the areas of health, toxicology, and medicine. Recognized for its high impact, it occupies a top-ranking position in Scopus, with remarkable quartile placements in 2023, categorizing it as Q1 in Health, Toxicology and Mutagenesis, and Q1 in Medicine (Miscellaneous). The journal highlights critical research and innovative methodologies, appealing to a diverse audience of researchers, professionals, and students committed to understanding the complexities of toxic substances and their implications for public health and environmental safety. The journal does not currently offer open access, allowing for a more traditional but rigorous peer-review process that ensures the quality and integrity of every published article. Join the global discourse in toxicological science with ARCHIVES OF TOXICOLOGY, where every contribution furthers the understanding of safety and toxicity in our world.
TOXICOLOGY AND INDUSTRIAL HEALTH
Empowering professionals with insights on toxic substances and safety.TOXICOLOGY AND INDUSTRIAL HEALTH, published by SAGE PUBLICATIONS INC, is a premier journal in the field of toxicology, public health, and environmental health, with a significant history dating back to 1985. With its ISSN 0748-2337 and E-ISSN 1477-0393, the journal provides a platform for disseminating groundbreaking research and comprehensive reviews that address the complexities of toxic substances in industrial and occupational settings. Despite its Q3 ranking among peers in health, toxicology, and public health, this journal is becoming increasingly influential, reflected in its growing citation metrics. Researchers and professionals benefit from its commitment to fostering knowledge in both theoretical and practical contexts, making it an essential resource for those dedicated to advancing understanding in this vital field. The journal's main objectives include promoting research addressing the implications of toxicology on health and safety standards across industries, ensuring accessibility to current studies for a global audience. Overall, TOXICOLOGY AND INDUSTRIAL HEALTH plays a critical role in bridging the gap between research and real-world applications, proving invaluable to students, professionals, and researchers alike in their pursuit of enhancing public health and environmental safety.
European Journal of Pharmacology
Exploring the frontiers of therapeutic applications and drug development.The European Journal of Pharmacology, a prestigious publication by Elsevier, serves as a vital resource in the field of pharmacology, offering rich insights into drug development and therapeutic applications. Since its inception in 1967, this journal has evolved to encompass groundbreaking research, including pharmacokinetics, toxicology, and innovative pharmacological methodologies, making it an essential platform for researchers and professionals alike. With an impressive impact factor that places it in the Q1 category of pharmacological journals and a Scopus ranking of #49 out of 313, the journal is recognized in the 84th percentile within its category, solidifying its significance in the academic community. Although the journal is not open access, it continues to attract contributions from leading scientists worldwide, ensuring that cutting-edge findings are disseminated effectively. The European Journal of Pharmacology not only highlights advancements in drug discovery and clinical applications but also promotes interdisciplinary collaboration, ultimately contributing to the progress of healthcare globally.
CHEMICAL RESEARCH IN TOXICOLOGY
Unveiling the complexities of chemical toxicity for a safer future.Chemical Research in Toxicology is a premier journal published by the American Chemical Society, dedicated to advancing the understanding of toxicological effects associated with chemical substances. Since its inception in 1988, this esteemed journal has maintained a robust impact factor, ranking in the Q1 quartile for both Medicine (miscellaneous) and Toxicology as of 2023, reflecting its significance and influence in the fields of pharmacology and toxicology. With an impressive Scopus ranking at #16 out of 133 in the Toxicology category, it serves as a vital resource for researchers, professionals, and students seeking cutting-edge insights and scholarly articles that bridge the gap between chemistry and toxicological science. Although not an open-access publication, it continues to provide comprehensive analyses and original research that inform safe chemical practices and regulatory policies, further enhancing its role in public health and safety.
TOXICOLOGY MECHANISMS AND METHODS
Exploring innovative methodologies in toxicology research.TOXICOLOGY MECHANISMS AND METHODS is a distinguished peer-reviewed journal dedicated to the advancement of toxicological research, published by Taylor & Francis Ltd. With its ISSN 1537-6516 and E-ISSN 1537-6524, this esteemed journal features critical studies and innovative methodologies in the field of toxicology, aligning with its mission to enhance understanding of biological mechanisms and risk assessment. The journal holds a commendable Q2 ranking in both the Health, Toxicology and Mutagenesis, and Toxicology categories, as well as strong positions in Scopus rankings, reflecting its influence with a 71st percentile rank in Toxicology and a 69th percentile rank in Environmental Health. Researchers, professionals, and students in the toxicology domain will find this journal to be an invaluable resource, offering open access options that foster widespread dissemination of its findings. Since its inception, encompassing converged years from 1991 to 1995 and from 2002 to 2024, the journal remains at the forefront of critical discourse and innovative research methods, making it a vital platform for advancing toxicological science globally.
INHALATION TOXICOLOGY
Advancing the Science of Airborne Hazards.Inhalation Toxicology, published by Taylor & Francis Ltd, is a premier journal dedicated to advancing the field of toxicology with a particular focus on inhalation exposure and its impact on human health. Established in 1989, this journal provides a vital platform for original research, reviews, and case studies that explore the toxicological effects of inhaled substances, making it essential reading for researchers, health professionals, and regulatory scientists. With an Impact Factor that situates it in the Q3 category in both Health, Toxicology and Mutagenesis, the journal asserts its relevance within the scientific community, particularly emphasizing its contributions as indexed by Scopus rankings in related fields. Although it follows a traditional access model, the journal's commitment to delivering high-quality research continues to foster significant discussions and advancements in understanding inhalation toxicology. For those at the forefront of environmental science and pharmacology, Inhalation Toxicology is an indispensable resource for both current research and future innovations in the discipline.
Molecular & Cellular Toxicology
Unraveling the molecular mysteries of toxic responses.Molecular & Cellular Toxicology, published by the Korean Society Toxicogenomics & Toxicoproteomics (KSTT), is a significant journal in the field of toxicology, providing crucial insights into molecular mechanisms underlying toxic responses. With an ISSN of 1738-642X and E-ISSN 2092-8467, this journal serves as a vital platform for researchers, professionals, and students interested in the latest findings and advancements in toxicology, health, and environmental science. Although it operates under a subscription model, it maintains rigorous peer review standards, contributing to its respectable Q3 classification in Health, Toxicology and Mutagenesis, and its Q2 standing in Pharmacology, Toxicology, and Pharmaceutics. The journal, intersecting with innovative aspects of pharmacology and public health, aims to foster a deeper understanding of toxicological impacts on cellular processes and overall health. Located in Germany and supported by a dedicated editorial board, Molecular & Cellular Toxicology stands out in the academic community, encouraging interdisciplinary discourse and collaboration to address critical toxicological challenges. Engage with us for cutting-edge research that informs and shapes the future of toxicological science.
DRUG AND CHEMICAL TOXICOLOGY
Decoding the impacts of chemicals on human health.Drug and Chemical Toxicology is a well-respected journal in the fields of toxicology, pharmacology, and public health, published by Taylor & Francis Ltd. Since its inception in 1978, this journal has diligently explored the effects and mechanisms of chemical exposures on health and the environment, fulfilling a crucial role in advancing scientific understanding and safeguarding public health. The journal is indexed across prestigious databases and features an impressive array of articles categorized within the Q2 and Q3 quartiles across various categories in 2023, reflecting its significance in Chemical Health and Safety as well as Environmental and Occupational Health disciplines. With an extensive reach and a focus on interdisciplinary research, Drug and Chemical Toxicology offers a rich repository of original research, reviews, and methodological advancements, catering to a diverse audience of researchers, professionals, and students dedicated to the betterment of safety and health standards. Although not an open-access publication, its articles are widely accessible to the academic community, ensuring that critical innovations and insights are shared for the greater good.
TOXICOLOGIC PATHOLOGY
Pioneering Research for a Safer, Healthier FutureTOXICOLOGIC PATHOLOGY, published by SAGE Publications Inc., is a dedicated journal that serves as a pivotal platform for researchers and professionals in the fields of toxicology and pathology. With an ISSN of 0192-6233 and E-ISSN of 1533-1601, the journal has been committed to advancing knowledge since its inception in 1972. It boasts impressive rankings in the recent 2023 category quartiles, achieving Q2 in Pathology and Forensic Medicine, and Q3 in Cell Biology, Molecular Biology, and Toxicology, marking it as a significant contributor to these vital disciplines. Despite its non-open access status, the journal ensures accessibility through various premium library subscriptions, providing readers with essential insights on toxicologic and pathologic research, advancing both academic inquiry and practical applications. Researchers, students, and industry professionals alike will find TOXICOLOGIC PATHOLOGY an indispensable resource, offering high-quality peer-reviewed articles that explore the complex interactions between substances and biological systems, with the aim of improving public health and safety.