Computational Toxicology

Scope & Guideline

Innovating the future of environmental health through computation.

Introduction

Delve into the academic richness of Computational Toxicology with our guidelines, detailing its aims and scope. Our resource identifies emerging and trending topics paving the way for new academic progress. We also provide insights into declining or waning topics, helping you stay informed about changing research landscapes. Evaluate highly cited topics and recent publications within these guidelines to align your work with influential scholarly trends.
LanguageEnglish
ISSN2468-1113
PublisherELSEVIER
Support Open AccessNo
CountryNetherlands
TypeJournal
Convergefrom 2017 to 2024
AbbreviationCOMPUT TOXICOL / Comput. Toxicol.
Frequency4 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
AddressRADARWEG 29, 1043 NX AMSTERDAM, NETHERLANDS

Aims and Scopes

Computational Toxicology focuses on leveraging computational methods and models to assess chemical safety, predict toxicological effects, and support regulatory decisions. The journal emphasizes innovative methodologies and interdisciplinary approaches that integrate toxicology, bioinformatics, and cheminformatics.
  1. Quantitative Structure-Activity Relationship (QSAR) Modeling:
    Utilizing mathematical and statistical techniques to predict the toxicity of chemical compounds based on their molecular structure, enabling risk assessment without extensive animal testing.
  2. Adverse Outcome Pathways (AOPs):
    Developing frameworks that describe the relationship between chemical exposure and adverse health effects, facilitating the understanding of mechanisms of toxicity.
  3. Physiologically-Based Kinetic (PBK) Modeling:
    Creating models that simulate the absorption, distribution, metabolism, and excretion (ADME) of chemicals in biological systems, aiding in the prediction of human and environmental exposure.
  4. Machine Learning and Artificial Intelligence Applications:
    Employing advanced computational techniques to enhance predictive accuracy in toxicology, including the classification of toxic effects and the identification of potential chemical hazards.
  5. Nanotoxicology and Environmental Toxicology:
    Investigating the toxicological implications of nanomaterials and environmental chemicals, focusing on their interactions with biological systems.
  6. Chemical Safety Assessment and Regulatory Frameworks:
    Supporting the integration of computational approaches into regulatory practices to ensure the safe use of chemicals in various industries.
Recent publications in Computational Toxicology highlight several emerging themes that are gaining momentum. These trends indicate a proactive response to the evolving landscape of toxicological research and regulatory needs.
  1. Integration of Big Data and High-Throughput Screening:
    The use of large datasets combined with high-throughput screening technologies is on the rise, enabling more comprehensive analyses of chemical toxicity and enhancing predictive models.
  2. Development of New Approach Methodologies (NAMs):
    There is a growing emphasis on NAMs, which utilize innovative in silico and in vitro methodologies to enhance the safety assessment process and reduce reliance on animal testing.
  3. Focus on Environmental and Human Health Risk Assessment:
    Emerging themes include the assessment of environmental chemicals and their impact on human health, especially in light of increased regulatory scrutiny.
  4. Personalized Toxicology and Risk Assessment:
    The incorporation of genetic and biological variability in toxicity assessments is becoming more prevalent, facilitating personalized approaches to toxicological risk management.
  5. Advancements in Computational Methods for Mixture Toxicology:
    Research is increasingly addressing the complexities of chemical mixtures and their combined effects, reflecting a more holistic approach to toxicology.

Declining or Waning

As the field of computational toxicology evolves, certain themes have shown a decline in focus or frequency of publication. This reflects shifting priorities and advancements in methodologies.
  1. Traditional In Vivo Toxicology Studies:
    There is a noticeable reduction in reliance on traditional animal testing methods as computational approaches gain traction, reflecting a broader acceptance of in silico predictions.
  2. Basic Toxicity Screening Methods:
    Basic screening methods that do not leverage advanced computational techniques are becoming less prominent, as more sophisticated models provide better predictive capabilities.
  3. Single Endpoint Toxicity Assessments:
    The shift towards integrated approaches that consider multiple endpoints and mechanisms of action has led to a decline in the publication of studies focused solely on single toxicity endpoints.

Similar Journals

JOURNAL OF ANALYTICAL TOXICOLOGY

Empowering Safety Through Analytical Excellence
Publisher: OXFORD UNIV PRESS INCISSN: 0146-4760Frequency: 9 issues/year

JOURNAL OF ANALYTICAL TOXICOLOGY, published by Oxford University Press Inc, stands as a leading platform in the field of analytical chemistry and toxicology, focusing on the rigorous exploration of methodologies and advancements in the detection of toxic substances. Since its inception in 1977, this journal has continually contributed to the scientific community, providing researchers and professionals with vital insights into chemical health, safety, and environmental implications. With an impressive Q1 ranking in both Analytical Chemistry and Chemical Health and Safety, along with reputable Q2 rankings in Environmental Chemistry and Toxicology, the journal maintains its critical standing in vibrant academic communities, ensuring the dissemination of high-quality research. Although it currently does not offer open access, articles are made available via institutional subscriptions, allowing widespread access to its valuable findings. Located in the United States, the journal contains a wealth of knowledge poised to benefit scientists and scholars engaged in toxicological research, emphasizing its importance in enhancing public health and safety.

Molecular Informatics

Bridging Computational Techniques with Biological Innovation
Publisher: WILEY-V C H VERLAG GMBHISSN: 1868-1743Frequency: 12 issues/year

Molecular Informatics is a prestigious journal published by WILEY-V C H VERLAG GMBH, dedicated to advancing the fields of computational analysis and molecular modeling. As a key resource in the realms of Computer Science Applications, Drug Discovery, Molecular Medicine, Organic Chemistry, and Structural Biology, this journal is recognized for its significant contributions and is ranked in the Q2 and Q3 categories across multiple disciplines, positioning it among the leading journals for researchers and academics. With an impressive track record since its inception in 2010 and converging its contributions until 2024, Molecular Informatics aims to bridge the gap between computational techniques and biological applications, promoting interdisciplinary collaboration and innovation. Accessible to a global audience, the journal reflects a commitment to advancing science through open access options, making cutting-edge research available to students, professionals, and decision-makers alike. This journal serves as an indispensable platform for disseminating high-quality research and fostering the development of new theoretical and practical frameworks in molecular informatics.

Toxin Reviews

Pioneering Insights in Toxicology Since 1982
Publisher: TAYLOR & FRANCIS INCISSN: 1556-9543Frequency: 4 issues/year

Toxin Reviews is a premier academic journal focused on the critical field of Toxicology, published by Taylor & Francis Inc. Established with an aim to foster research and disseminate knowledge, this journal has been pivotal since its inception in 1982 and continues to be a leading platform for both emerging and established researchers. With an impressive impact factor and ranked in the 75th percentile among its peers in the Scopus categories, it serves as an essential resource for scientists, practitioners, and students interested in understanding the complexities of toxins and their effects on health. The journal provides an Open Access platform, enhancing visibility and accessibility of research findings to a broader audience. Covering a wide scope, Toxin Reviews plays a vital role in bridging gaps between toxicological research and practical applications, ensuring that rigorous scientific inquiry translates into real-world solutions.

INHALATION TOXICOLOGY

Elevating Knowledge in Inhalation Toxicology.
Publisher: TAYLOR & FRANCIS LTDISSN: 0895-8378Frequency: 14 issues/year

Inhalation Toxicology, published by Taylor & Francis Ltd, is a premier journal dedicated to advancing the field of toxicology with a particular focus on inhalation exposure and its impact on human health. Established in 1989, this journal provides a vital platform for original research, reviews, and case studies that explore the toxicological effects of inhaled substances, making it essential reading for researchers, health professionals, and regulatory scientists. With an Impact Factor that situates it in the Q3 category in both Health, Toxicology and Mutagenesis, the journal asserts its relevance within the scientific community, particularly emphasizing its contributions as indexed by Scopus rankings in related fields. Although it follows a traditional access model, the journal's commitment to delivering high-quality research continues to foster significant discussions and advancements in understanding inhalation toxicology. For those at the forefront of environmental science and pharmacology, Inhalation Toxicology is an indispensable resource for both current research and future innovations in the discipline.

CRITICAL REVIEWS IN TOXICOLOGY

Elevating Understanding of Chemical Risks and Impacts
Publisher: TAYLOR & FRANCIS LTDISSN: 1040-8444Frequency: 10 issues/year

CRITICAL REVIEWS IN TOXICOLOGY, published by Taylor & Francis Ltd, stands as a preeminent journal within the field of toxicology, boasting an impressive Q1 ranking and holding the distinction of being ranked 12th out of 133 in the toxicology category according to Scopus, placing it in the top 91st percentile. With a continuous publication history since 1971 and a commitment to providing high-quality reviews, the journal offers critical insight into the latest research and advancements in toxicological sciences. While it is not an open-access journal, it provides numerous access options for both subscribers and institutions, ensuring that its extensive articles are widely available to the academic community. The journal's objectives are to disseminate comprehensive reviews that foster understanding and innovation in the assessment of chemical risks, environmental impacts, and the mechanisms of toxicity, making it an invaluable resource for researchers, professionals, and students dedicated to the science of toxicology.

TOXICOLOGY LETTERS

Driving innovation in the study of toxic substances.
Publisher: ELSEVIER IRELAND LTDISSN: 0378-4274Frequency: 20 issues/year

TOXICOLOGY LETTERS is a prominent journal dedicated to advancing the field of toxicology, providing a platform for high-quality research and reviews that explore the effects of chemical substances on biological systems. Published by Elsevier Ireland Ltd, this peer-reviewed journal has established itself as a vital resource in toxicological research since its inception in 1977, with a convergence of studies extending to 2024. With an impressive Scopus ranking, positioned at #28 out of 133 in the Toxicology category, TOXICOLOGY LETTERS garners a respectable percentile of 79, highlighting its significance in the academic community. Although it is not an open-access journal, its research is accessible through institutional subscriptions, ensuring that critical insights into human health and environmental safety are disseminated effectively. Being categorized in the Q2 quartile in both Medicine (miscellaneous) and Toxicology for 2023 further emphasizes its relevance and impact in these fields. This journal aims to foster collaboration between researchers and professionals, encouraging the exploration of innovative solutions to chemical hazards and the promotion of safer practices in pharmacology and toxicology.

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Unveiling the impacts of toxins on ecosystems and society.
Publisher: SPRINGERISSN: 0007-4861Frequency: 12 issues/year

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, published by SPRINGER, is a pivotal journal in the fields of Environmental Science, Toxicology, and Public Health. With a strong history of dissemination since its inception in 1966, the journal predominantly focuses on the latest advances in understanding environmental contaminants and their toxicological effects on health and ecosystems. It currently holds a respectable Q2 ranking across multiple categories including Health, Toxicology and Mutagenesis, Medicine (miscellaneous), and Pollution, as per the 2023 metrics. While the journal is not Open Access, it provides an invaluable platform for researchers, professionals, and students seeking to contribute to and stay informed on critical issues regarding environmental hazards and their implications. With an engaged community of scholars and practitioners, this journal continues to be an essential resource for addressing the pressing challenges of environmental contamination and its health impacts, guiding future research and policy decisions.

Particle and Fibre Toxicology

Connecting science to toxicological realities.
Publisher: BMCISSN: 1743-8977Frequency: 1 issue/year

Particle and Fibre Toxicology is a leading open-access journal dedicated to advancing the field of toxicology, specifically focusing on the health impacts of particulate matter and fibers. Published by BMC since 2004, this journal operates from its offices in the United Kingdom and has gained significant recognition in the scientific community, achieving an impressive impact factor that highlights its relevance and influence. As indicated by its Q1 ranking in various categories including Health, Toxicology and Mutagenesis and Medicine (miscellaneous), it occupies a prestigious position in the academic landscape, appealing to researchers, professionals, and students alike. With a Scopus ranking of #4 in Toxicology and #7 in Environmental Science, the journal ensures high visibility and accessibility, providing a platform for the dissemination of key research findings and innovative methodologies in the interdisciplinary domains of toxicology. Through its commitment to open access, Particle and Fibre Toxicology fosters knowledge-sharing and collaboration, facilitating significant advancements in our understanding of the toxicological effects of environmental agents.

SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Advancing Environmental Insights through Molecular Relationships.
Publisher: TAYLOR & FRANCIS LTDISSN: 1062-936XFrequency: 12 issues/year

SAR and QSAR in Environmental Research is a leading journal published by Taylor & Francis Ltd, focusing on the integration of Structure-Activity Relationships (SAR) and Quantitative Structure-Activity Relationships (QSAR) within the realm of environmental science. Since its inception in 1993, the journal has been a pivotal platform for disseminating innovative research that bridges the gap between chemistry and environmental sustainability, ranking in the Q3 quartile for Bioengineering, Drug Discovery, and miscellaneous Medicine categories as of 2023. Featuring a compelling collection of peer-reviewed articles, it caters to academic and professional audiences seeking to enhance their understanding of molecular interactions and their implications for environmental health. Although the journal does not currently offer Open Access options, its rigorous editorial standards ensure high-quality, impactful publications that are crucial for advancing methodologies in pharmacology, toxicology, and bioengineering. With an ISSN of 1062-936X and an E-ISSN of 1029-046X, SAR and QSAR in Environmental Research continues to serve as an essential resource for researchers, academics, and practitioners dedicated to innovative approaches in environmental research.

REGULATORY TOXICOLOGY AND PHARMACOLOGY

Elevating Standards in Toxicology and Pharmacology Research
Publisher: ACADEMIC PRESS INC ELSEVIER SCIENCEISSN: 0273-2300Frequency: 9 issues/year

REGULATORY TOXICOLOGY AND PHARMACOLOGY is a prestigious peer-reviewed journal published by Academic Press Inc. Elsevier Science, dedicated to advancing knowledge in the fields of toxicology and pharmacology. With an esteemed impact factor and a current ranking of Q2 in both Medicine and Toxicology, this journal serves as a critical resource for researchers, professionals, and students interested in the regulatory aspects of drug safety and environmental toxicology. The journal publishes original research articles, reviews, and regulatory updates that reflect the latest insights and methodologies in safety assessment and toxicological research. Established in 1970, the journal continues to play an integral role in shaping the scientific discourse around regulatory practices in pharmacology, ensuring that both academic and practical perspectives are captured. Readers can access the articles through subscription services, allowing them to stay informed of the most significant developments in the field.