CURRENT GENE THERAPY
Scope & Guideline
Bridging Research and Clinical Practice.
Introduction
Aims and Scopes
- Gene Therapy Innovations:
The journal highlights breakthroughs in gene therapy methodologies, exploring both established and novel techniques for delivering therapeutic genes to target cells. - Cancer Research and Treatment:
A significant focus is placed on the application of gene therapy in oncology, investigating therapeutic strategies for various cancers, including personalized medicine approaches. - Neurodegenerative Disorders:
CURRENT GENE THERAPY features research on gene therapy applications aimed at treating neurodegenerative diseases, emphasizing advancements in targeting and delivery systems. - Regulatory and Ethical Considerations:
The journal discusses the regulatory landscape surrounding gene therapy, including safety assessments, clinical trial designs, and ethical implications of genetic modifications. - Research on Non-Coding RNAs:
There is a consistent focus on the role of non-coding RNAs in gene regulation and their potential as therapeutic targets in various diseases.
Trending and Emerging
- CRISPR and Genome Editing Technologies:
Research on CRISPR-based gene editing continues to rise, focusing on its applications in therapeutic contexts, including cancer and genetic disorders, showcasing its potential for precision medicine. - Theranostics in Cancer Treatment:
The integration of diagnostic and therapeutic approaches, particularly concerning the use of biomarkers in conjunction with gene therapy, is an emerging trend that enhances personalized treatment strategies. - Non-Coding RNA Therapeutics:
There is a growing interest in the therapeutic potential of non-coding RNAs, with research focusing on their role in gene regulation and their applications in treating various diseases. - Nanoparticle and Vector Development:
Innovations in nanoparticle and viral vector technologies for gene delivery are increasingly prominent, as researchers seek to improve targeted delivery and reduce immunogenicity. - Immunotherapy and Gene Therapy Synergy:
The combination of gene therapy with immunotherapeutic strategies is gaining attention as a promising avenue for enhancing treatment efficacy in cancer and other diseases.
Declining or Waning
- Traditional Small Molecule Therapies:
Research on traditional pharmacological approaches has diminished as the field increasingly emphasizes genetic and molecular therapies, reflecting a shift towards more innovative genetic solutions. - General Stem Cell Therapies:
The focus on broad stem cell applications is waning in favor of targeted gene therapies, particularly those that utilize stem cells specifically for gene delivery or modification. - Basic Mechanistic Studies:
There is a noted decline in publications centered solely on basic mechanistic studies without a direct therapeutic application, as the journal increasingly prioritizes translational research.
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