CANCER RESEARCH
Scope & Guideline
Exploring the depths of cancer prevention and diagnosis.
Introduction
Aims and Scopes
- Cancer Biology and Mechanisms:
Research exploring the molecular and cellular mechanisms underlying cancer initiation, progression, and metastasis, including studies on genetic mutations, epigenetic alterations, and the tumor microenvironment. - Therapeutic Strategies and Drug Development:
Investigations into novel therapeutic approaches, including targeted therapies, immunotherapies, and combination treatments, aimed at improving clinical outcomes for cancer patients. - Biomarkers and Prognostic Indicators:
Studies focused on identifying and validating biomarkers that can predict cancer progression, treatment response, and patient prognosis, aiding in personalized medicine. - Clinical Trials and Translational Research:
Reports on clinical trials evaluating new treatments, surgical techniques, and interventions, bridging the gap between laboratory research and patient care. - Cancer Epidemiology and Risk Factors:
Research analyzing epidemiological data to identify risk factors associated with various cancer types, contributing to prevention strategies and public health initiatives. - Innovative Methodologies:
Development and application of cutting-edge techniques, such as machine learning, genomic sequencing, and advanced imaging, to enhance cancer research and diagnostics.
Trending and Emerging
- Immunotherapy and Immune Microenvironment:
A significant increase in studies focusing on immunotherapy, including checkpoint inhibitors and CAR T-cell therapy, as researchers explore the immune landscape's role in cancer progression and treatment response. - Targeted Therapy and Precision Medicine:
Emerging research on targeted therapies that exploit specific genetic alterations within tumors, alongside studies on biomarkers for patient stratification and personalized treatment plans. - Role of Non-Coding RNAs:
A growing body of literature investigating the functions of long non-coding RNAs (lncRNAs) and microRNAs in cancer biology, particularly their roles in regulating gene expression, cancer stemness, and treatment resistance. - Metabolic Reprogramming in Cancer:
Research focusing on the metabolic adaptations of cancer cells, including the study of pathways like glycolysis and ferroptosis, as potential targets for therapeutic intervention. - Multi-Omics Approaches:
An increase in studies utilizing multi-omics strategies (genomics, transcriptomics, proteomics) to gain comprehensive insights into cancer biology and identify novel therapeutic targets.
Declining or Waning
- Traditional Chemotherapy Studies:
Research centered on conventional chemotherapy regimens has decreased as newer targeted therapies and immunotherapies gain traction, leading to a shift in focus toward more personalized and effective treatment modalities. - Basic Research on Non-Malignant Conditions:
Investigations into benign tumors and non-cancerous conditions have become less frequent, as the journal prioritizes research that directly impacts cancer treatment and understanding. - Single-Agent Drug Studies:
The prevalence of studies evaluating the efficacy of single-agent drugs has waned, with a growing emphasis on combination therapies and multi-targeted approaches to overcome resistance and enhance treatment outcomes.
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