FEBS Open Bio
Scope & Guideline
Exploring the depths of biochemistry, genetics, and beyond.
Introduction
Aims and Scopes
- Biochemical and Molecular Biology:
Research focused on the biochemical processes that underlie cellular functions, including enzyme mechanisms, metabolic pathways, and molecular interactions. - Cell Biology and Physiology:
Studies examining cellular processes, signaling pathways, and physiological responses in various cell types, including investigations into cancer biology and stem cell research. - Structural Biology and Biophysics:
Research involving the structural characterization of biological macromolecules using techniques such as X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy. - Genomics and Transcriptomics:
Exploration of gene expression patterns, genetic variations, and their implications for health and disease using high-throughput sequencing technologies. - Microbiology and Immunology:
Investigations into microbial biology, host-pathogen interactions, and the immune responses to infections and diseases. - Biotechnology and Bioengineering:
Research focused on the application of biological knowledge for technological advancements, including drug development, synthetic biology, and biomanufacturing. - Environmental and Ecological Studies:
Studies assessing the interactions between biological organisms and their environments, including the impact of climate change and pollution on ecosystems.
Trending and Emerging
- CRISPR and Genome Editing Technologies:
The use of CRISPR technology for genome editing is rapidly expanding, with applications ranging from gene therapy to crop improvement, reflecting its transformative potential in biology. - Microbiome Research and Its Implications:
Studies exploring the human microbiome and its role in health and disease are on the rise, highlighting the importance of microbial communities in various biological processes. - Synthetic Biology and Biomanufacturing:
Research focused on engineering biological systems for the production of biofuels, pharmaceuticals, and other valuable compounds is gaining momentum as sustainability becomes a priority. - Personalized Medicine and Biomarkers:
The identification of biomarkers for personalized treatment strategies in various diseases, especially cancer, is a growing area of interest, driven by advances in genomics and biochemistry. - Cellular Mechanotransduction:
Investigations into how cells sense and respond to mechanical stimuli are emerging as significant, particularly in the context of tissue engineering and regenerative medicine. - Immunotherapy and Cancer Treatment Innovations:
Research into novel immunotherapeutic approaches, including CAR-T cell therapy and immune checkpoint inhibitors, is rapidly advancing, reflecting a shift towards targeted cancer therapies.
Declining or Waning
- Classical Biochemistry Techniques:
Research utilizing traditional biochemical methods may be declining as newer, more advanced techniques such as CRISPR and high-throughput sequencing gain popularity. - Single-Cell Analysis in Non-Cancer Contexts:
While single-cell analysis remains a hot topic in cancer research, its application in other biological contexts may be waning as focus shifts towards more integrated approaches. - Basic Microbiology Studies:
Research that does not translate into applied microbiology or clinical relevance may be declining, as journals increasingly favor studies with direct implications for health or industry. - In Vivo Models of Disease:
The reliance on in vivo models may be decreasing as alternative methods, such as organ-on-a-chip technologies and computational models, become more prominent. - Studies with Limited Interdisciplinary Approach:
Papers that do not incorporate interdisciplinary methods or collaborations may be less favored, reflecting a trend towards integrative research.
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