INTERNATIONAL REVIEWS OF IMMUNOLOGY
Scope & Guideline
Catalyzing Collaboration in Immunology
Introduction
Aims and Scopes
- Investigation of Immune Mechanisms:
The journal consistently publishes research examining the underlying mechanisms of immune responses, including both innate and adaptive immunity, and their roles in various diseases. - Therapeutic Innovations in Immunology:
A significant focus is placed on novel therapeutic approaches, such as immunotherapy, vaccine development, and the use of biological agents to modulate immune responses. - Interdisciplinary Approaches:
The journal promotes interdisciplinary research, integrating immunology with other fields such as microbiology, oncology, and bioinformatics, to provide a holistic understanding of immune interactions. - Emerging Infectious Diseases:
The journal addresses the immunological aspects of emerging infectious diseases, notably the response to new pathogens and the immune challenges posed by pandemics, such as COVID-19. - Role of Metabolism in Immunity:
Research exploring the interplay between metabolism and immune function has become a core area, highlighting how metabolic pathways influence immune cell behavior and disease outcomes.
Trending and Emerging
- Cancer Immunotherapy:
There is a notable increase in research related to cancer immunotherapy, including CAR-T cell therapy and immune checkpoint inhibitors, underscoring the growing importance of harnessing the immune system against tumors. - Microbiome and Immunity:
Research exploring the relationship between the gut microbiome and immune responses is gaining traction, highlighting its role in health and disease, particularly in autoimmune and inflammatory conditions. - Single-Cell Analysis Techniques:
The adoption of single-cell RNA sequencing and other high-resolution techniques is on the rise, allowing for detailed profiling of immune cell populations and their functional states in various contexts. - Immunometabolism:
The integration of immunology with metabolic research is emerging as a key theme, focusing on how metabolic pathways influence immune cell function and contribute to disease pathology. - Regulatory T Cells and Immune Tolerance:
There is an increasing interest in understanding the role of regulatory T cells in maintaining immune tolerance, particularly in the context of autoimmune diseases and transplantation.
Declining or Waning
- Traditional Vaccine Research:
Research focused on traditional vaccine formulations and methodologies has decreased, possibly as the field shifts towards innovative and personalized vaccine strategies. - Basic Mechanisms of Disease:
There seems to be a decline in publications solely dedicated to basic immunological mechanisms in diseases, with a growing preference for studies that connect these mechanisms to therapeutic applications. - Historical Perspectives on Immunology:
Papers that provide historical insights or reviews on classical immunological concepts are less frequent, as the focus has moved towards cutting-edge research and contemporary issues in immunology.
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