NATURE REVIEWS CANCER
Scope & Guideline
Pioneering Knowledge in Cancer Prevention and Treatment
Introduction
Aims and Scopes
- Cancer Biology and Mechanisms:
The journal explores the fundamental biological processes underlying cancer, including cellular signaling, genetic mutations, and tumor microenvironment interactions. - Therapeutic Strategies and Innovations:
It investigates novel therapeutic approaches, including targeted therapies, immunotherapies, and emerging treatment modalities, aiming to enhance patient outcomes. - Epidemiology and Public Health:
Research on cancer epidemiology, risk factors, and public health implications is a core focus, addressing disparities and the impact of environmental factors on cancer incidence. - Translational Research and Clinical Applications:
The journal emphasizes the translation of laboratory findings into clinical practice, highlighting studies that bridge the gap between research and patient care. - Emerging Technologies in Cancer Research:
NATURE REVIEWS CANCER discusses the application of cutting-edge technologies such as genomics, proteomics, and artificial intelligence in cancer research and treatment. - Patient-Centric Research and Care:
The journal promotes research that centers on patient experiences, outcomes, and the integration of patient perspectives in cancer care.
Trending and Emerging
- Immunotherapy and Immune Microenvironment:
There has been a significant increase in studies focusing on the role of the immune system in cancer, particularly regarding immunotherapy and the tumor immune microenvironment. - AI and Machine Learning Applications:
The integration of artificial intelligence and machine learning in cancer diagnosis, treatment planning, and research methodologies has gained momentum, reflecting technological advancements in the field. - Patient-Derived Models and Organoids:
Research utilizing patient-derived tumor models and organoids is on the rise, emphasizing personalized medicine and the importance of studying cancer in a more physiologically relevant context. - Microbiome and Cancer Interactions:
An emerging theme is the exploration of the gut and tumor microbiome's role in cancer initiation and progression, highlighting the importance of microbiota in cancer biology. - Sex and Racial Disparities in Cancer:
There is a growing emphasis on understanding how sex and racial disparities affect cancer outcomes, treatment responses, and genetic predispositions, aiming for more equitable healthcare solutions.
Declining or Waning
- Traditional Chemotherapy:
Research focusing solely on traditional chemotherapy regimens has decreased, as newer targeted and immunotherapeutic strategies gain prominence. - Basic Cancer Genetics:
While genetics remains crucial, the emphasis has shifted from basic genetic studies to more complex interactions involving epigenetics and the tumor microenvironment. - Single-Agent Therapies:
There is a waning interest in studies that focus on single-agent therapies, as combination therapies and multi-modal approaches are becoming more favored in the literature. - Non-Clinical Models:
Research that relies solely on non-clinical models without translational implications is less frequently published, with a stronger emphasis on studies that can inform clinical practice. - Conventional Imaging Techniques:
There is a notable decline in the publication of papers centered on conventional imaging techniques, as advanced imaging technologies and multiplex approaches are increasingly favored.
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