NUCLEIC ACIDS RESEARCH

Scope & Guideline

Pioneering Research in Molecular Biology

Introduction

Welcome to the NUCLEIC ACIDS RESEARCH information hub, where our guidelines provide a wealth of knowledge about the journal’s focus and academic contributions. This page includes an extensive look at the aims and scope of NUCLEIC ACIDS RESEARCH, highlighting trending and emerging areas of study. We also examine declining topics to offer insight into academic interest shifts. Our curated list of highly cited topics and recent publications is part of our effort to guide scholars, using these guidelines to stay ahead in their research endeavors.
LanguageEnglish
ISSN0305-1048
PublisherOXFORD UNIV PRESS
Support Open AccessYes
CountryUnited Kingdom
TypeJournal
Convergefrom 1974 to 2024
AbbreviationNUCLEIC ACIDS RES / Nucleic Acids Res.
Frequency22 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
AddressGREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND

Aims and Scopes

NUCLEIC ACIDS RESEARCH is a leading journal that focuses on the latest research in the fields of nucleic acids, molecular biology, and related areas. The journal aims to disseminate high-quality research articles that explore the structure, function, and dynamics of nucleic acids, as well as their implications in various biological processes and diseases.
  1. Nucleic Acid Structure and Function:
    Research focusing on the structural and functional aspects of DNA and RNA, including studies on G-quadruplexes, ribozymes, and RNA modifications.
  2. Gene Regulation and Expression:
    Explorations of the mechanisms that control gene expression, including transcription factors, enhancers, silencers, and the role of non-coding RNAs.
  3. DNA Repair and Replication:
    Investigations into the molecular mechanisms of DNA repair pathways, replication processes, and the impact of various factors on genomic integrity.
  4. CRISPR and Genome Editing Technologies:
    Studies on the development and application of CRISPR and other genome editing technologies, including their mechanisms, efficiency, and specificity.
  5. Epigenetics and Chromatin Dynamics:
    Research addressing the role of epigenetic modifications and chromatin structure in regulating gene expression and maintaining genomic stability.
  6. Bioinformatics and Computational Biology:
    Development and application of computational tools and databases for analyzing nucleic acid sequences, structures, and interactions.
NUCLEIC ACIDS RESEARCH has seen a surge in interest in several emerging themes that reflect current trends in nucleic acid research. These themes highlight innovative methodologies and significant biological implications.
  1. RNA Modifications and Function:
    Research focusing on various RNA modifications, such as m6A and pseudouridylation, is gaining momentum, emphasizing their roles in gene regulation, stability, and cellular responses.
  2. CRISPR Technologies and Applications:
    There is a rapidly growing body of work exploring novel CRISPR applications, including base editing, epigenome editing, and their therapeutic potential in various diseases.
  3. Synthetic Biology and RNA Engineering:
    Emerging studies on engineered RNA molecules and synthetic biology approaches are trending, particularly in the context of developing novel therapeutics and gene regulation systems.
  4. Phase Separation and Biomolecular Condensates:
    Research on the role of phase separation in cellular organization and function is increasingly prominent, particularly in relation to RNA-binding proteins and their interactions.
  5. Metagenomics and Microbiome Studies:
    The integration of nucleic acid research with metagenomics and microbiome analysis is on the rise, showcasing the importance of microbial communities in health and disease.
  6. Machine Learning in Genomics:
    The application of machine learning techniques to analyze genomic data and predict functional outcomes is an emerging trend, facilitating more efficient data interpretation and discovery.

Declining or Waning

While NUCLEIC ACIDS RESEARCH continues to thrive, certain research areas have shown a decline in frequency or interest over recent years. These waning scopes may reflect shifts in scientific focus or emerging priorities within the broader field.
  1. Traditional Molecular Biology Techniques:
    There has been a notable decrease in publications centered around classical molecular biology techniques, such as basic cloning and PCR methods, which have been largely supplanted by more advanced and sophisticated technologies.
  2. Single-Gene Studies:
    Research focusing on the characterization of single genes has diminished, as the field increasingly moves towards understanding complex interactions and networks involving multiple genes and regulatory elements.
  3. Static Structural Studies:
    Static studies that provide a snapshot of molecular structures without dynamic considerations are becoming less prominent, as researchers prioritize studies that incorporate dynamic and functional aspects of nucleic acids.
  4. Basic RNA Isolation Techniques:
    The frequency of articles dedicated solely to basic RNA isolation and purification techniques has decreased, as researchers now often integrate these methods within broader studies of RNA function and dynamics.

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