Pharmacogenetics and Genomics

Scope & Guideline

Pioneering research for a tailored approach to drug therapy.

Introduction

Welcome to your portal for understanding Pharmacogenetics and Genomics, featuring guidelines for its aims and scope. Our guidelines cover trending and emerging topics, identifying the forefront of research. Additionally, we track declining topics, offering insights into areas experiencing reduced scholarly attention. Key highlights include highly cited topics and recently published papers, curated within these guidelines to assist you in navigating influential academic dialogues.
LanguageEnglish
ISSN1744-6872
PublisherLIPPINCOTT WILLIAMS & WILKINS
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 2005 to 2024
AbbreviationPHARMACOGENET GENOM / Pharmacogenet. Genomics
Frequency9 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
AddressTWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103

Aims and Scopes

The journal "Pharmacogenetics and Genomics" focuses on the intersection of pharmacogenetics and clinical practice, emphasizing how genetic variations influence drug responses and efficacy. Its core aim is to advance personalized medicine through the integration of genetic testing in therapeutic decisions.
  1. Pharmacogenetic Variability and Drug Response:
    The journal extensively covers research that elucidates how genetic polymorphisms affect individual responses to medications, including efficacy and toxicity, thereby contributing to personalized treatment strategies.
  2. Clinical Implementation of Pharmacogenetics:
    A significant focus is on the practical application of pharmacogenetic testing in clinical settings, evaluating how such implementations can enhance patient care and treatment outcomes.
  3. Genetic Mechanisms and Pathways:
    Research published in the journal often explores the biological mechanisms underlying pharmacogenetic variability, including gene-drug interactions and metabolic pathways.
  4. Population-Specific Pharmacogenetics:
    The journal highlights studies that investigate pharmacogenetic variations across different populations, addressing disparities in drug response and treatment effectiveness.
  5. Emerging Technologies in Pharmacogenomics:
    The integration of new technologies such as CRISPR, genome-wide association studies, and high-throughput sequencing is a consistent theme, driving advancements in pharmacogenetic research.
The journal has witnessed a rise in certain themes that reflect current trends and emerging areas of interest within pharmacogenetics and genomics. These trends signify the evolving landscape of personalized medicine.
  1. Integration of Pharmacogenomics in Clinical Guidelines:
    There is an increasing focus on how pharmacogenomic data can be incorporated into clinical guidelines, enhancing decision-making in drug therapy and improving patient outcomes.
  2. Research on Polygenic Risk Scores:
    Studies exploring polygenic risk scores to predict drug response and adverse effects are gaining traction, highlighting the complexity of genetic influences on pharmacotherapy.
  3. Pharmacogenetics in Oncology:
    An emerging theme is the application of pharmacogenetics in oncology, where genetic variations are linked to responses to chemotherapy and targeted therapies, driving personalized cancer treatment.
  4. Real-World Evidence and Implementation Studies:
    There is a significant increase in research utilizing real-world data to assess the impact of pharmacogenetic testing on treatment outcomes, reflecting a shift towards practical applications in healthcare.
  5. Patient-Centric Pharmacogenetic Research:
    New studies are emphasizing patient perspectives and experiences regarding pharmacogenetic testing, indicating a trend towards more holistic approaches in pharmacogenomics.

Declining or Waning

While the journal continues to thrive in various areas of pharmacogenetics, some themes have shown a decline in focus over recent years, reflecting shifts in research priorities and emerging scientific interests.
  1. Traditional Drug Interaction Studies:
    Research centered solely on traditional drug-drug interactions, without considering genetic factors, appears less frequently, as the field moves towards a more integrated approach that includes genetic profiling.
  2. Single Gene Studies:
    There is a noticeable reduction in studies focusing exclusively on single gene polymorphisms, as the field increasingly embraces comprehensive genomic approaches and polygenic risk scores.
  3. General Population Studies:
    Investigations that do not account for specific demographic or ethnic variations are becoming less common, reflecting a trend towards more nuanced research that recognizes the importance of population genetics.
  4. Basic Science without Clinical Application:
    Research that remains purely within the domain of basic science, without a clear path to clinical application or relevance, is less frequently published, indicating a shift towards translational research.

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