THROMBOSIS RESEARCH
Scope & Guideline
Transforming Understanding of Blood Clotting Mechanisms
Introduction
Aims and Scopes
- Thrombosis Mechanisms and Pathophysiology:
Research exploring the underlying mechanisms of thrombosis, including genetic, molecular, and cellular factors that contribute to thrombus formation and resolution. - Clinical Management of Thrombotic Disorders:
Studies focused on the clinical aspects of thrombosis management, including treatment protocols, anticoagulation strategies, and patient outcomes across various conditions, particularly in cancer and surgery. - Impact of Anticoagulants and Novel Therapies:
Evaluating the efficacy and safety of anticoagulant therapies, including direct oral anticoagulants (DOACs), low molecular weight heparins, and emerging treatments in diverse patient populations. - Risk Assessment and Predictive Models:
Development and validation of risk assessment tools and models to predict thrombotic events in various clinical settings, enhancing patient stratification and management. - Thrombosis and Systemic Conditions:
Investigations into the relationship between thrombosis and systemic diseases, including infections, autoimmune disorders, and malignancies, highlighting the complexity of coagulation in these contexts. - Innovative Diagnostic Techniques:
Research on novel diagnostic methodologies for the detection and monitoring of thrombotic conditions, including imaging techniques and biomarker assessments.
Trending and Emerging
- COVID-19 and Thrombosis:
An increasing number of studies are investigating the thrombotic complications associated with COVID-19, including mechanisms, risk factors, and management strategies, indicating a significant shift in research focus due to the pandemic. - Cancer-Associated Thrombosis:
There is a marked rise in research related to thrombosis in cancer patients, exploring the complexities of managing thrombotic events in this vulnerable population and the implications of anticancer therapies on thrombotic risk. - Machine Learning and Predictive Analytics:
Emerging themes in the application of machine learning and predictive analytics for thrombotic risk assessment and management, showcasing the integration of technology and data science in clinical practice. - Patient-Centered Approaches:
A growing emphasis on patient-reported outcomes and experiences related to thrombotic conditions and their management, reflecting a broader trend towards personalized medicine. - Thrombosis in Pediatric Populations:
An increase in studies focusing on thrombosis in pediatric patients, highlighting the unique challenges and considerations in this demographic, including implications for long-term health. - Interdisciplinary Research:
An upward trend in interdisciplinary studies that explore the intersection of thrombosis with other medical fields, such as immunology and cardiology, indicating a holistic approach to understanding thrombotic diseases.
Declining or Waning
- Traditional Anticoagulant Therapies:
There seems to be a declining emphasis on older anticoagulant therapies, such as vitamin K antagonists, as research increasingly focuses on direct oral anticoagulants and their advantages. - Basic Laboratory Studies in Thrombosis:
A reduction in basic laboratory research related to thrombosis mechanisms, with a shift towards clinical and translational studies that directly impact patient care. - Isolated Studies on Specific Thrombosis Types:
Fewer publications are addressing isolated forms of thrombosis, such as superficial vein thrombosis, as the journal's focus expands to encompass broader, more integrated studies that consider multiple thrombotic events and their systemic implications.
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