Annual Review of Pathology-Mechanisms of Disease

Scope & Guideline

Pioneering Research in the Mechanisms of Disease

Introduction

Immerse yourself in the scholarly insights of Annual Review of Pathology-Mechanisms of Disease with our comprehensive guidelines detailing its aims and scope. This page is your resource for understanding the journal's thematic priorities. Stay abreast of trending topics currently drawing significant attention and explore declining topics for a full picture of evolving interests. Our selection of highly cited topics and recent high-impact papers is curated within these guidelines to enhance your research impact.
LanguageEnglish
ISSN1553-4006
PublisherANNUAL REVIEWS
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 2006 to 2021, from 2023 to 2024
AbbreviationANNU REV PATHOL-MECH / Annu. Rev. Pathol.-Mech. Dis.
Frequency1 issue/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address4139 EL CAMINO WAY, PO BOX 10139, PALO ALTO, CA 94303-0139

Aims and Scopes

The Annual Review of Pathology: Mechanisms of Disease serves as a critical platform for disseminating comprehensive reviews that synthesize current research on the pathophysiological mechanisms underlying various diseases. The journal emphasizes the interplay between molecular biology, genetics, and environmental factors in disease progression, making it a cornerstone for researchers in pathology and related fields.
  1. Mechanisms of Disease Pathogenesis:
    The journal focuses on elucidating the underlying mechanisms of various diseases, including cancer, infectious diseases, and genetic disorders, providing insights into how these mechanisms contribute to disease progression and potential therapeutic targets.
  2. Translational Research:
    A significant emphasis is placed on bridging basic research with clinical applications, facilitating the translation of laboratory findings into clinical practice to improve diagnosis, treatment, and prevention strategies.
  3. Innovations in Diagnostic Techniques:
    The journal explores advancements in diagnostic methodologies, including imaging techniques, biomarker discovery, and molecular profiling, which enhance the accuracy and efficiency of disease detection.
  4. Interdisciplinary Approaches:
    The publication encourages interdisciplinary research that integrates pathology with fields such as immunology, genetics, and bioinformatics, promoting a holistic understanding of disease mechanisms.
  5. Emerging Therapeutics:
    The journal highlights novel therapeutic strategies, including precision medicine and targeted therapies, which are informed by a deeper understanding of disease biology, to improve patient outcomes.
In recent years, the Annual Review of Pathology: Mechanisms of Disease has identified several emerging themes that reflect the dynamic nature of research in pathology. These themes highlight areas of increasing interest and innovation within the field.
  1. Artificial Intelligence in Pathology:
    Recent publications have increasingly focused on the application of artificial intelligence and machine learning techniques in pathology, particularly for improving diagnostic accuracy and personalizing treatment strategies.
  2. Role of the Microenvironment in Disease:
    There is a growing interest in understanding how the tumor microenvironment and other tissue microenvironments influence disease progression, particularly in cancer and inflammatory diseases.
  3. Epigenetics and Disease Mechanisms:
    Research on epigenetic modifications and their roles in disease pathogenesis is gaining traction, reflecting the recognition of epigenetics as a crucial factor in gene expression regulation and disease development.
  4. Neuroinflammation and Neurodegeneration:
    The interplay between neuroinflammation and neurodegenerative diseases, particularly in the context of conditions like Alzheimer's and Parkinson's disease, has emerged as a significant area of focus, highlighting the importance of inflammation in neurological health.
  5. Metabolic Pathways in Disease:
    An increasing number of studies are examining the links between metabolic dysregulation and various diseases, including cancer and chronic inflammatory conditions, emphasizing the role of metabolism in pathophysiology.

Declining or Waning

While the Annual Review of Pathology: Mechanisms of Disease maintains a broad focus on various aspects of disease mechanisms, certain themes have shown a decline in prominence over recent years. This shift may reflect changing research priorities or advancements in related fields.
  1. Classic Pathological Techniques:
    There has been a noticeable decrease in publications focusing on traditional pathological methods such as histopathology and microscopy, as newer techniques and technologies have emerged to provide more detailed insights into disease mechanisms.
  2. General Disease Overviews:
    Papers that provide broad, non-specific overviews of diseases without a focus on specific mechanisms or advancements are becoming less common, indicating a shift towards more specialized and detailed analyses.
  3. Non-Molecular Approaches:
    Research that emphasizes non-molecular aspects of disease, such as purely clinical observations or epidemiological studies without a focus on underlying mechanisms, appears to be declining in favor of more molecularly-driven investigations.

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