BIOLOGICALS
Scope & Guideline
Driving innovation in applied biology and pharmacology.
Introduction
Aims and Scopes
- Biological Therapeutics Development:
The journal emphasizes research on the development of biological products, including vaccines and monoclonal antibodies, highlighting innovative approaches and methodologies. - Quality Control and Assurance:
A significant focus is placed on the quality control processes for biological products, including validation of assays and detection of contaminants. - Regulatory Frameworks:
The journal covers the regulatory aspects surrounding biological products, providing insights into international standards, national regulations, and compliance challenges. - Vaccine Research and Development:
There is a consistent emphasis on vaccine R&D, including novel vaccine candidates, formulations, and delivery systems. - Infectious Diseases and Immunology:
Research addressing infectious diseases, immune responses, and the implications of vaccination strategies is a core area of interest. - Emerging Technologies in Biologicals:
The journal explores the integration of new technologies in the development and manufacturing of biologicals, such as mRNA vaccines and nanoparticle formulations.
Trending and Emerging
- Advancements in mRNA Technology:
The rise of mRNA vaccines has spurred a significant increase in research related to their development, production, and evaluation, particularly in light of COVID-19. - Real-World Evidence in Vaccine Deployment:
There is an emerging trend towards utilizing real-world evidence to inform regulatory decisions and public health strategies for vaccine deployment. - Nanotechnology in Vaccine Delivery:
Research into nanoparticle formulations and other nanotechnologies for vaccine delivery systems is rapidly gaining momentum, highlighting their potential to enhance immunogenicity. - Ethical and Regulatory Considerations:
A growing emphasis on the ethical implications and regulatory challenges surrounding the development and use of biologicals is emerging, particularly in the context of animal welfare and human trials. - Multi-epitope and Combination Vaccines:
The exploration of multi-epitope vaccines and combination strategies is trending, reflecting a shift towards more comprehensive approaches in addressing complex infectious diseases.
Declining or Waning
- Traditional Vaccine Potency Testing:
There has been a noticeable decline in publications centered around traditional in vivo potency testing methods for vaccines, as newer, more humane in vitro alternatives gain traction. - General Virology Studies:
While virology remains important, the specific focus on broad virology studies without a direct application to biologicals or therapeutics has decreased, possibly due to a shift toward more targeted research. - Conventional Monoclonal Antibody Development:
Research centered solely on conventional methods for monoclonal antibody development has waned, with a growing preference for innovative approaches and biosimilar comparisons. - Non-regulatory Laboratory Practices:
There seems to be a reduction in emphasis on non-regulatory laboratory practices, as the focus shifts towards compliance and regulatory issues in the context of biologicals.
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