CELLULAR SIGNALLING

Scope & Guideline

Transforming Understanding of Cellular Dynamics

Introduction

Welcome to the CELLULAR SIGNALLING information hub, where our guidelines provide a wealth of knowledge about the journal’s focus and academic contributions. This page includes an extensive look at the aims and scope of CELLULAR SIGNALLING, highlighting trending and emerging areas of study. We also examine declining topics to offer insight into academic interest shifts. Our curated list of highly cited topics and recent publications is part of our effort to guide scholars, using these guidelines to stay ahead in their research endeavors.
LanguageEnglish
ISSN0898-6568
PublisherELSEVIER SCIENCE INC
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 1989 to 2024
AbbreviationCELL SIGNAL / Cell. Signal.
Frequency12 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
AddressSTE 800, 230 PARK AVE, NEW YORK, NY 10169

Aims and Scopes

The journal 'CELLULAR SIGNALLING' focuses on exploring the intricate mechanisms of cellular signaling pathways and their implications in various physiological and pathological processes. This encompasses a broad spectrum of biological systems, with a particular emphasis on how cellular signals influence disease progression, treatment responses, and therapeutic interventions.
  1. Cellular Signaling Mechanisms:
    Investigation of the molecular pathways involved in cellular signaling, including receptor activation, second messenger systems, and downstream effectors.
  2. Pathophysiological Implications:
    Exploration of how dysregulation in signaling pathways contributes to various diseases, including cancer, cardiovascular disorders, and metabolic diseases.
  3. Therapeutic Targets and Drug Development:
    Identification of novel therapeutic targets within signaling pathways and the development of small molecules or biological agents aimed at modulating these pathways for therapeutic benefit.
  4. Role of Non-Coding RNAs:
    Analysis of the involvement of non-coding RNAs, including microRNAs and long non-coding RNAs, in the regulation of cellular signaling and their implications in disease.
  5. Intercellular Communication:
    Study of how cellular signaling affects intercellular interactions, particularly in the tumor microenvironment and immune responses.
The journal 'CELLULAR SIGNALLING' has identified several trending and emerging themes that reflect the evolving landscape of research in cellular signaling, particularly in relation to disease mechanisms and therapeutic strategies.
  1. Ferroptosis and Its Role in Disease:
    Research on ferroptosis, a form of regulated cell death characterized by iron-dependent lipid peroxidation, has surged, highlighting its implications in cancer, neurodegeneration, and organ damage.
  2. Exosome-Mediated Signaling:
    The exploration of exosomes as mediators of cellular communication and signaling has gained traction, emphasizing their role in cancer progression and potential as biomarkers.
  3. Immunomodulatory Signaling Pathways:
    The study of how cellular signaling pathways modulate immune responses, particularly in the context of cancer immunotherapy, has become increasingly prominent.
  4. Integrative Multi-Omics Approaches:
    There is a growing trend towards integrating various omics data (genomics, transcriptomics, proteomics) to provide a holistic view of cellular signaling networks and their implications in health and disease.
  5. CircRNAs in Cancer Biology:
    Research focusing on circular RNAs (circRNAs) as regulators of gene expression and their roles in cancer has emerged as a significant area of interest, revealing novel mechanisms of action.

Declining or Waning

While 'CELLULAR SIGNALLING' continues to thrive in various research areas, certain topics have seen a decline in focus, possibly reflecting shifts in the research landscape or emerging priorities in cellular signaling studies.
  1. Basic Research on Traditional Pathways:
    There has been a noticeable decrease in publications focusing solely on well-established signaling pathways (e.g., MAPK, PI3K) without new insights or applications, as the field moves towards more integrative and complex signaling interactions.
  2. Single-Cell Analysis Studies:
    Though still important, the frequency of studies solely relying on single-cell analysis techniques has waned as researchers adopt multi-omics approaches that provide a more comprehensive view of cellular signaling.
  3. Studies on Non-Mammalian Models:
    Research utilizing non-mammalian model organisms for signaling studies has diminished, likely due to a greater emphasis on mammalian systems that more directly correlate with human health.
  4. In Vitro Studies Without Translational Relevance:
    There is a shift away from in vitro studies that do not demonstrate clear translational relevance to human diseases, as the journal increasingly prioritizes research with potential clinical applications.

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