Cell Stress
Scope & Guideline
Exploring the Intersection of Health and Molecular Biology
Introduction
Aims and Scopes
- Cellular Stress Mechanisms:
This area encompasses studies on how cells respond to various stressors, including oxidative stress, nutrient deprivation, and mechanical stress, exploring pathways like autophagy and apoptosis. - Cancer Biology and Therapy:
The journal focuses on the role of stress responses in cancer development, progression, and treatment, including the investigation of novel therapeutic targets and strategies to overcome cancer resistance. - Microbiota and Health:
Research on the interaction between microbiota and host health, particularly in relation to metabolic diseases and cancer, highlighting the impact of gut health on overall well-being. - Neurological Disorders:
Exploration of the cellular stress responses in neurodegenerative diseases, including Alzheimer's and Huntington's, with an emphasis on autophagy and mitochondrial function. - Immunology and Inflammation:
Studies that examine the role of cellular stress in immune responses, inflammation, and the implications for disease and therapy, particularly in cancer and autoimmune diseases. - Metabolism and Aging:
Research on how cellular stress impacts metabolic pathways and aging processes, investigating potential interventions to promote healthspan and lifespan.
Trending and Emerging
- Liquid-Liquid Phase Separation in Cellular Processes:
An increasing number of studies are investigating the role of phase separation in cellular functions, particularly in relation to cancer biology and stress responses. - Psychosocial Factors in Health:
Research exploring the psychosocial aspects of health and disease, particularly how stress affects psychosocial adaptation, is gaining attention, indicating a holistic approach to health. - Microbiota's Role in Disease Modulation:
Emerging themes focus on the gut microbiota's influence on various diseases, particularly in cancer therapy and metabolic disorders, showcasing the interplay between microbiota and host health. - Senolytics and Aging Research:
There is a growing interest in senolytic compounds and their potential to target aging cells, reflecting an increasing focus on longevity and healthspan. - Immunotherapy Advances in Oncology:
The journal is increasingly publishing on innovative immunotherapeutic strategies, particularly those that enhance T cell function against tumors, indicating a shift towards personalized cancer therapies.
Declining or Waning
- Traditional Cancer Therapies:
There is a noticeable reduction in studies focusing on conventional cancer treatment modalities, like chemotherapy, as newer, more targeted therapies gain traction. - Basic Mechanistic Studies:
Research that solely explores basic mechanisms of cellular stress without translational applications is becoming less frequent, indicating a shift towards studies with direct clinical relevance. - In Vivo Studies of Non-Cancerous Conditions:
The emphasis on in vivo studies related to non-cancerous conditions has decreased, possibly because of a growing focus on cancer and its treatments.
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