GENES & DEVELOPMENT

Scope & Guideline

Exploring the Frontiers of Gene Function and Development

Introduction

Explore the comprehensive scope of GENES & DEVELOPMENT through our detailed guidelines, including its aims and scope. Stay updated with trending and emerging topics, and delve into declining areas to understand shifts in academic interest. Our guidelines also showcase highly cited topics, featuring influential research making a significant impact. Additionally, discover the latest published papers and those with high citation counts, offering a snapshot of current scholarly conversations. Use these guidelines to explore GENES & DEVELOPMENT in depth and align your research initiatives with current academic trends.
LanguageEnglish
ISSN0890-9369
PublisherCOLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
Support Open AccessNo
CountryUnited States
TypeJournal
Convergefrom 1987 to 2024
AbbreviationGENE DEV / Genes Dev.
Frequency24 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address1 BUNGTOWN RD, COLD SPRING HARBOR, NY 11724

Aims and Scopes

The journal 'GENES & DEVELOPMENT' focuses on the intricate processes of gene expression and regulation, cellular development, and the molecular mechanisms driving biological functions. It serves as a platform for cutting-edge research that integrates genetics, developmental biology, and molecular biology, with an emphasis on understanding the underlying principles of gene function in health and disease.
  1. Gene Regulation and Expression:
    Research on the mechanisms of gene regulation, including transcriptional and post-transcriptional control, RNA processing, and the roles of non-coding RNAs.
  2. Developmental Biology:
    Studies that explore the genetic and molecular basis of development across various organisms, emphasizing how genes orchestrate complex developmental processes.
  3. Cancer Biology:
    Investigations into the genetic and epigenetic alterations that lead to cancer, focusing on the roles of specific genes and pathways in tumorigenesis and metastasis.
  4. Stem Cell Biology and Regeneration:
    Research focused on the mechanisms that govern stem cell behavior, differentiation, and tissue regeneration, including the environmental and genetic factors that influence these processes.
  5. Epigenetics and Chromatin Dynamics:
    Exploration of how epigenetic modifications and chromatin structure affect gene expression and cellular identity, with implications for development and disease.
  6. Cellular Responses to Stress and Damage:
    Studies investigating how cells respond to DNA damage and environmental stress, including the roles of signaling pathways and repair mechanisms.
  7. Model Organisms in Genetics:
    Utilization of model organisms such as Drosophila, zebrafish, and mice to uncover fundamental biological principles applicable to higher organisms.
The landscape of research published in 'GENES & DEVELOPMENT' is evolving, with several emerging themes gaining traction in recent years. This section outlines the trending areas that reflect current scientific inquiries and technological advancements.
  1. RNA Biology and Regulation:
    An increasing emphasis on the roles of RNA in gene regulation, including the functions of non-coding RNAs, RNA modifications, and RNA-protein interactions, highlighting the complexity of gene expression control.
  2. Cancer Genomics and Precision Medicine:
    A surge in research focusing on the genetic underpinnings of cancer, particularly studies that link genomic alterations to therapeutic strategies, emphasizing personalized medicine approaches.
  3. Epigenetic Mechanisms and Therapy:
    Growing interest in understanding epigenetic modifications and their potential as therapeutic targets, particularly in cancer and developmental disorders.
  4. Cellular Mechanisms of Aging and Regeneration:
    Emerging studies investigating the cellular and molecular mechanisms underlying aging and regenerative processes, with implications for developmental biology and therapeutics.
  5. Systems Biology and Multi-Omics Approaches:
    An increase in the application of systems biology and multi-omics techniques to study complex biological systems, integrating genomics, transcriptomics, proteomics, and metabolomics.
  6. Neurogenetics and Neurodevelopmental Disorders:
    A rising focus on the genetic basis of neurological conditions, emphasizing developmental processes and the impact of genetic variants on brain function and disease.

Declining or Waning

While 'GENES & DEVELOPMENT' maintains a robust focus on various aspects of gene function and development, certain themes appear to be waning in prominence over recent years. This section highlights these declining areas of research, reflecting shifts in scientific interest and advancements in technology.
  1. Classical Genetics:
    There has been a noticeable decline in the publication of papers focused on classical genetic studies, such as Mendelian inheritance patterns, as the field shifts towards more complex genetic interactions and molecular mechanisms.
  2. In vitro Models:
    Research utilizing traditional in vitro cell culture models is becoming less common, as there is a trend towards more sophisticated in vivo models and organoid systems that better mimic physiological conditions.
  3. Basic Biochemical Pathways:
    While foundational research into basic biochemical pathways remains important, there has been a gradual decrease in studies that solely describe these pathways without integrating them into broader biological contexts.
  4. Single-Gene Studies:
    The focus on individual genes and their functions is less prevalent as the field moves towards understanding gene networks and interactions within larger biological systems.

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