Molecular Oncology
Scope & Guideline
Connecting the Dots in Cancer Biology and Treatment.
Introduction
Aims and Scopes
- Molecular Characterization of Tumors:
The journal emphasizes studies that delve into the molecular and genetic underpinnings of various cancers, including the identification of biomarkers and therapeutic targets. - Cancer Stem Cells and Tumor Microenvironment:
Research on cancer stem cells and their interactions with the tumor microenvironment is a core focus, exploring how these elements contribute to tumorigenesis and therapeutic resistance. - Innovative Therapeutic Strategies:
Molecular Oncology seeks to publish novel therapeutic approaches, including targeted therapies, immunotherapies, and combination treatments that leverage molecular insights to improve cancer care. - Liquid Biopsy and Non-Invasive Diagnostics:
The journal encourages research on liquid biopsy techniques and other non-invasive methods for early cancer detection, monitoring treatment responses, and understanding tumor evolution. - Translational Research:
There is a strong emphasis on translational research that bridges laboratory findings with clinical applications, aiming to enhance patient outcomes through precision medicine.
Trending and Emerging
- Multi-Omics Approaches:
There is a growing trend towards multi-omics studies that integrate genomics, transcriptomics, proteomics, and metabolomics to provide a comprehensive view of cancer biology and therapy responses. - Microbiome and Cancer Interactions:
Research exploring the interactions between the microbiome and cancer is gaining traction, highlighting the influence of microbial communities on tumor development and treatment outcomes. - Immunotherapy and Immune Profiling:
The focus on immunotherapy continues to expand, with increasing research on immune profiling, checkpoint inhibitors, and the tumor microenvironment's role in shaping immune responses. - Artificial Intelligence and Computational Methods:
The application of artificial intelligence and machine learning in analyzing cancer data is on the rise, facilitating the identification of novel therapeutic targets and enhancing predictive modeling. - Targeting Metabolic Pathways:
There is a notable increase in studies targeting cancer metabolism, reflecting a deeper understanding of how metabolic reprogramming supports tumor growth and resistance.
Declining or Waning
- Traditional Chemotherapy Resistance Mechanisms:
Research focused solely on traditional chemotherapy resistance mechanisms is declining, as there is a shift towards understanding more complex interactions involving the tumor microenvironment and cancer stem cells. - Single-Agent Therapeutic Studies:
There is a noticeable decrease in studies that examine the efficacy of single-agent therapies, as the focus is increasingly on combination therapies and multi-target approaches that show greater promise in overcoming resistance. - Basic Epidemiological Studies:
Papers that primarily focus on basic epidemiological data without molecular insights are becoming less frequent, as the field moves towards integrating molecular biology with epidemiology for a more comprehensive understanding of cancer. - Generalized Cancer Biomarkers:
The exploration of generalized cancer biomarkers is waning, with more emphasis now placed on specific, actionable biomarkers that can guide targeted therapies and personalized medicine.
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