OncoTargets and Therapy
Scope & Guideline
Bridging knowledge and practice in cancer care.
Introduction
Aims and Scopes
- Cancer Therapeutics:
The journal focuses on the development and evaluation of novel therapeutic strategies for various cancers, including chemotherapy, targeted therapy, immunotherapy, and combination therapies. - Molecular Mechanisms of Cancer:
Research articles often explore the underlying molecular and cellular mechanisms that contribute to cancer development, progression, and treatment resistance, with a particular emphasis on signaling pathways and gene expression. - Biomarkers and Prognostic Indicators:
The identification and validation of biomarkers for cancer diagnosis, prognosis, and treatment response are central themes, helping to personalize therapy and improve patient outcomes. - Clinical Case Studies:
The journal publishes clinical case reports that highlight unique therapeutic responses, novel treatment applications, and insights into cancer management, contributing to the clinical understanding of oncology. - Translational Research:
OncoTargets and Therapy promotes translational research that bridges the gap between laboratory findings and clinical applications, facilitating the development of new diagnostic and therapeutic strategies.
Trending and Emerging
- Immunotherapy Advances:
The increasing focus on immunotherapy, particularly checkpoint inhibitors and CAR-T cell therapies, reflects the growing recognition of the immune system's role in cancer treatment and the need for novel immunotherapeutic strategies. - Targeted Therapy Innovations:
Research on targeted therapies, especially those targeting specific genetic mutations (e.g., EGFR, ALK), has surged, demonstrating a trend towards precision medicine in oncology. - Long Non-Coding RNAs (lncRNAs):
There is a rising interest in the role of lncRNAs in cancer biology, particularly their involvement in tumor progression, metastasis, and chemoresistance, highlighting their potential as therapeutic targets. - Circular RNAs in Cancer:
The exploration of circular RNAs as regulatory molecules in cancer has gained momentum, with studies investigating their roles in tumorigenesis and potential as biomarkers or therapeutic targets. - Liquid Biopsy Techniques:
Emerging research on liquid biopsies for cancer detection and monitoring reflects a trend towards non-invasive methods for assessing tumor dynamics and treatment response, paving the way for more personalized patient management.
Declining or Waning
- Traditional Chemotherapy Focus:
The emphasis on traditional chemotherapy regimens has diminished as newer targeted therapies and immunotherapies have gained prominence, leading to a reduced number of studies centered on conventional chemotherapy. - Single-Agent Therapies:
There is a noticeable decline in research focusing solely on single-agent therapies, as the trend has shifted towards combination therapies that leverage synergistic effects for improved efficacy. - Basic Science Research Without Clinical Application:
Papers that focus purely on basic biological mechanisms without direct clinical implications or translational relevance appear to be less frequent, as the journal increasingly prioritizes research with clear applications to patient care. - Epidemiological Studies:
The number of epidemiological studies related to cancer has decreased, possibly due to a shift towards more molecular and targeted approaches in cancer research. - Focus on Rare Cancers:
Research focusing on rare cancers, while still important, has seen a reduction in publication frequency as the journal emphasizes more common malignancies that have larger patient populations and treatment implications.
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