Drug Metabolism and Pharmacokinetics

Scope & Guideline

Pioneering Research in Drug Metabolism and Pharmacokinetics

Introduction

Welcome to your portal for understanding Drug Metabolism and Pharmacokinetics, featuring guidelines for its aims and scope. Our guidelines cover trending and emerging topics, identifying the forefront of research. Additionally, we track declining topics, offering insights into areas experiencing reduced scholarly attention. Key highlights include highly cited topics and recently published papers, curated within these guidelines to assist you in navigating influential academic dialogues.
LanguageEnglish
ISSN1347-4367
PublisherJAPANESE SOC STUDY XENOBIOTICS
Support Open AccessNo
CountryJapan
TypeJournal
Convergefrom 2002 to 2024
AbbreviationDRUG METAB PHARMACOK / Drug Metab. Pharmacokinet.
Frequency6 issues/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
AddressINT MED INF CENTER SHINANOMACHI RENGAKAN, 35 SHINANO-MACHI SHINJUKU-KU, TOKYO 160-0016, JAPAN

Aims and Scopes

The journal "Drug Metabolism and Pharmacokinetics" focuses on the intricate processes of drug metabolism, pharmacokinetics, and drug-drug interactions, emphasizing the importance of these areas in drug discovery and development.
  1. Drug Metabolism Mechanisms:
    Research on the biochemical processes by which drugs are metabolized in the body, including studies on cytochrome P450 enzymes and other metabolic pathways.
  2. Pharmacokinetic Modeling:
    Development and application of mathematical models to predict the absorption, distribution, metabolism, and excretion (ADME) of drugs, particularly through physiologically based pharmacokinetic (PBPK) models.
  3. Drug-Drug Interactions:
    Investigation of how different drugs affect each other's pharmacokinetics and pharmacodynamics, including the role of transporters and metabolic enzymes.
  4. Population Pharmacokinetics:
    Analysis of how drug pharmacokinetics vary among different populations, including genetic factors and ethnic differences.
  5. In Vitro and In Vivo Studies:
    Utilization of various experimental models, including animal models and human-derived systems, to study drug metabolism and pharmacokinetics.
  6. Emerging Technologies in Drug Development:
    Exploration of innovative methodologies such as machine learning, high-throughput screening, and organ-on-a-chip technologies to enhance drug development processes.
The journal has seen a surge in interest in several emerging themes, reflecting the ongoing evolution of drug metabolism and pharmacokinetics research.
  1. Physiologically Based Pharmacokinetic Modeling (PBPK):
    An increasing trend towards using PBPK modeling to predict drug behavior and interactions in humans, highlighting its importance in regulatory submissions and personalized medicine.
  2. Machine Learning Applications:
    Growing integration of machine learning techniques in pharmacokinetic modeling and drug discovery, enhancing the ability to predict drug metabolism and interactions.
  3. Microbiome Influence on Drug Metabolism:
    Emerging research on the role of gut microbiota in drug metabolism and pharmacokinetics, recognizing the significant impact of the microbiome on drug efficacy and safety.
  4. 3D Cell Culture Models:
    Increased use of advanced in vitro models, such as 3D cultures and organoids, for more accurate predictions of human drug metabolism and toxicity.
  5. Biomarker Identification for Drug Response:
    A trend towards identifying biomarkers that can predict individual responses to drugs, which is vital for the implementation of precision medicine.
  6. Focus on Rare Genetic Variants:
    An emerging emphasis on studying rare genetic variants in drug metabolism, recognizing their potential impact on drug efficacy and safety, particularly in diverse populations.

Declining or Waning

While the journal continues to explore a wide array of topics, certain themes have shown a decline in prominence, reflecting shifts in research focus and advancements in methodologies.
  1. Traditional Drug Interaction Studies:
    Research focused solely on traditional in vitro drug-drug interaction studies has been declining, as newer methodologies and models are developed that offer more predictive power.
  2. Animal Models in Drug Metabolism:
    There is a noticeable reduction in studies relying solely on animal models for drug metabolism research, with a shift towards more human-relevant in vitro systems and organoid models.
  3. Single Enzyme Studies:
    Investigations that focus on single enzyme activities without considering broader metabolic contexts and pathways are becoming less frequent, as there is a growing recognition of the complexity of drug metabolism.
  4. Generalized Pharmacogenomics:
    Research that does not take into account specific genetic variations in diverse populations is waning, as more studies emphasize personalized medicine and population-specific pharmacogenomics.

Similar Journals

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Fostering Collaboration for Transformative Medical Insights
Publisher: WILEYISSN: 0305-1870Frequency: 12 issues/year

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, published by WILEY, is a premier journal that serves as a vital resource for researchers, professionals, and students in the fields of pharmacology and physiology. With ISSN 0305-1870 and E-ISSN 1440-1681, this journal has established itself as a significant contributor to scientific dialogue since its inception in 1974. Currently spanning until 2024, it consistently publishes cutting-edge research addressing both experimental and clinical advancements in pharmacology and physiology. Recognized for its quality, it holds a Q2 ranking in the 2023 Pharmacology category and notable Q3 rankings in both Physiology and Medical Physiology. The journal's coverage of topical issues not only ensures a robust platform for innovative findings but also fosters collaborations across disciplines. Although not an Open Access journal, its curated content is invaluable for advancing knowledge, as evidenced by its solid Scopus rankings, which place it within the top percentiles of its field. Engaging with this journal means staying at the forefront of research that shapes clinical practices and experimental methodologies.

ADMET and DMPK

Elevating knowledge in ADMET and DMPK for a safer tomorrow.
Publisher: IAPC PUBLISHINGISSN: 1848-7718Frequency: 4 issues/year

ADMET and DMPK is a premier open-access journal published by IAPC PUBLISHING since 2013, focusing on the rapidly evolving fields of ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) and DMPK (Drug Metabolism and Pharmacokinetics). Catering to researchers, professionals, and students in the realms of pharmacology, toxicology, and medicinal chemistry, this journal plays a crucial role in fostering innovation and collaboration within the interdisciplinary landscape of drug development. With an impressive Q1 ranking in Pharmacology, Toxicology and Pharmaceutics and ranking in the top percentiles across various categories such as Chemistry and Health, ADMET and DMPK provides a reputable platform for high-quality publications. Its global reach, complemented by its open-access model, ensures that valuable research is accessible to a wide audience. As we converge towards 2024, this journal remains dedicated to advancing knowledge and practices that shape the future of drug discovery and safety, making it an essential resource in the scientific community.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Pioneering Research at the Intersection of Pharmacology and Science
Publisher: AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICSISSN: 0022-3565Frequency: 12 issues/year

The JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, published by the American Society for Pharmacology and Experimental Therapeutics, stands as a pivotal platform in the fields of pharmacology and molecular medicine. With an impressive convergence of knowledge from 1945 to 2024, this esteemed journal is recognized for its rigorous peer-reviewed research, contributing significantly to our understanding of drug action and therapeutic interventions. It holds a commendable position in the Q2 quartile in both Molecular Medicine and Pharmacology, emphasizing its relevance and impact within the contemporary scientific landscape, as evidenced by its Scopus ranking that places it amongst the leading journals in its category. Aimed at researchers, professionals, and students, the journal not only fosters a deeper insight into toxicology, pharmacodynamics, and therapeutic strategies but also encourages innovation through its comprehensive access to groundbreaking experimental methodologies. The journal continues to foster discourse and disseminate research that shapes the future of pharmacological science.

AAPS Journal

Advancing Pharmaceutical Knowledge, One Article at a Time.
Publisher: SPRINGERISSN: 1550-7416Frequency: 1 issue/year

AAPS Journal, published by Springer in the United States, is a leading peer-reviewed journal dedicated to the advancement of research in the field of Pharmaceutical Sciences. With an impressive Q1 rank in its category and a position within the 81st percentile of Scopus rankings, it serves as a vital resource for researchers and professionals seeking to disseminate impactful findings and innovative methodologies. The journal publishes high-quality original research, review articles, and technical reports aimed at addressing the multifaceted challenges in pharmacology, toxicology, and pharmaceutics. Operating under an Open Access model, AAPS Journal ensures broad dissemination of knowledge, contributing to the enhanced visibility and accessibility of research outputs. With a publication window spanning from 1999 to 2024, it continues to shape the future of pharmaceutical research and its applications. Researchers, students, and industry professionals will find a valuable repository of cutting-edge knowledge in this esteemed journal.

XENOBIOTICA

Bridging Disciplines for a Healthier Tomorrow.
Publisher: TAYLOR & FRANCIS LTDISSN: 0049-8254Frequency: 12 issues/year

XENOBIOTICA is a premier journal in the field of pharmacology and toxicology, published by Taylor & Francis Ltd. With an ISSN of 0049-8254 and E-ISSN 1366-5928, this journal has been at the forefront of research since 1971, providing critical insights and advancements up until 2024. It is recognized for its rigorous peer-reviewed content, occupying a third quartile ranking across various categories including Biochemistry, Health, Toxicology, and Pharmacology as of 2023. The journal serves as a pivotal platform for disseminating innovative findings that address the impact of xenobiotics on health and the environment, making it an essential resource for researchers, professionals, and students engaged in these multidisciplinary fields. While it does not currently offer open access, it is widely respected for its contribution to science, evidenced by its Scopus rankings across different areas of study. The journal encourages submissions that push the boundaries of knowledge and transform our understanding of the effects of chemical substances on living organisms.

ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Exploring the Nexus of Science and Drug Development
Publisher: MARY ANN LIEBERT, INCISSN: 1540-658XFrequency: 8 issues/year

ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES is a peer-reviewed journal published by Mary Ann Liebert, Inc., focused on the innovative fields of pharmacology and drug development. With its ISSN 1540-658X and E-ISSN 1557-8127, the journal has successfully contributed to the scientific community since its inception in 2002, converging into one comprehensive resource by 2024. Positioned in the Q3 quartile for Drug Discovery and Q4 for Molecular Medicine as per the 2023 rankings, the journal is dedicated to disseminating cutting-edge research that addresses the complexities of drug assay techniques and their implications in therapeutics. Although currently not an open-access publication, it offers significant insights and findings valuable to researchers, professionals, and students in the realm of biochemistry and pharmacology. With a commitment to advancing knowledge and innovation, ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES continues to be an essential platform for the latest advancements in drug discovery and development.

CURRENT DRUG METABOLISM

Bridging Discovery and Application in Drug Metabolism
Publisher: BENTHAM SCIENCE PUBL LTDISSN: 1389-2002Frequency: 14 issues/year

CURRENT DRUG METABOLISM, published by Bentham Science Publishers Ltd, serves as a pivotal resource in the fields of Clinical Biochemistry and Pharmacology. With an ISSN of 1389-2002 and an E-ISSN of 1875-5453, this journal has carved a niche since its inception in 2000, offering in-depth research and reviews that bridge the gap between drug metabolism and its clinical applications. The journal finds itself positioned in the third quartile (Q3) for both Clinical Biochemistry and Pharmacology as of 2023, reflecting its significance within these scientific sectors, with Scopus rankings showcasing its role in advancing knowledge—rank #167 in Pharmacology and #66 in Clinical Biochemistry. Researchers and industry professionals are encouraged to contribute their findings, fostering a diverse platform that informs and inspires innovations in drug development and safety. While CURRENT DRUG METABOLISM operates under a traditional subscription model without open access, its rigorous peer-review process ensures the quality and integrity of the published work, making it indispensable for anyone engaged in drug research and biochemistry.

ARCHIVES OF PHARMACAL RESEARCH

Showcasing impactful discoveries in organic chemistry and beyond.
Publisher: PHARMACEUTICAL SOC KOREAISSN: 0253-6269Frequency: 12 issues/year

Archives of Pharmacal Research, published by the Pharmaceutical Society of Korea, is a leading journal in the fields of drug discovery, molecular medicine, and organic chemistry. With an illustrious history spanning from 1978 to 2024, this peer-reviewed journal has earned a remarkable reputation, achieving a Q1 category ranking in each of its primary research areas as of 2023. Ranked #9 in Organic Chemistry and #12 in Drug Discovery among their respective fields, Archives of Pharmacal Research showcases cutting-edge research that contributes significantly to scientific advancements. Although it is not an open-access journal, its impactful publications are crucial resources for researchers, professionals, and students navigating the complexities of pharmacological sciences. The journal's continued commitment to disseminating high-quality research underlines its importance in fostering innovation and expanding knowledge within the pharmaceutical landscape.

DRUG METABOLISM AND DISPOSITION

Unraveling the Complexities of Drug Metabolism
Publisher: AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICSISSN: 0090-9556Frequency: 12 issues/year

Drug Metabolism and Disposition is a premier journal published by the American Society for Pharmacology and Experimental Therapeutics, focusing on crucial advancements in the fields of pharmaceutical sciences and pharmacology. Since its inception in 1973, this esteemed journal has established itself as a leading platform for innovative research, earning a prestigious Q1 rating in both Pharmaceutical Science and Pharmacology categories as of 2023. With an impressive Scopus ranking of #52 out of 183 in Pharmaceutical Science and #105 out of 313 in Pharmacology, it occupies a vital place in an increasingly competitive academic landscape. Researchers, professionals, and students alike benefit from its rigorous peer-reviewed articles that delve into drug metabolism processes and their physiological implications, making it an indispensable resource for anyone aiming to advance their understanding of drug disposition and efficacy. This crucial journal contributes significantly to the ongoing dialogue in pharmacology and toxicology, providing insights that help shape future therapeutic strategies and regulatory policies.

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Fostering Insights in Pharmacology and Toxicology for Better Health
Publisher: WILEYISSN: 1742-7835Frequency: 12 issues/year

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, published by WILEY, serves as a vital resource in the fields of medicine, pharmacology, and toxicology. With an ISSN of 1742-7835 and E-ISSN 1742-7843, this journal has established a robust reputation, reflected in its Q2 classification across its categories in 2023. It aims to disseminate high-quality research and reviews that bridge the gap between basic scientific findings and clinical applications. Operating from the United States with an address at 111 RIVER ST, HOBOKEN 07030-5774, NJ, this journal focuses on the intersection of drug action and toxicity, making it an essential platform for researchers, healthcare professionals, and students. With a converged publication timeline from 2004 to 2024, BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY continues to make significant contributions to understanding pharmacological treatments and toxicological challenges. Open access options are available to broaden the reach and impact of its published work.