Molecular Therapy Oncolytics

Scope & Guideline

Catalyzing Change in Cancer Treatment Strategies

Introduction

Welcome to your portal for understanding Molecular Therapy Oncolytics, featuring guidelines for its aims and scope. Our guidelines cover trending and emerging topics, identifying the forefront of research. Additionally, we track declining topics, offering insights into areas experiencing reduced scholarly attention. Key highlights include highly cited topics and recently published papers, curated within these guidelines to assist you in navigating influential academic dialogues.
LanguageEnglish
ISSN2372-7705
PublisherCELL PRESS
Support Open AccessYes
CountryUnited Kingdom
TypeJournal
Convergefrom 2014 to 2023
AbbreviationMOL THER ONCOLYTICS / Mol. Ther. Oncolytics
Frequency1 issue/year
Time To First Decision-
Time To Acceptance-
Acceptance Rate-
Home Page-
Address50 HAMPSHIRE ST, FLOOR 5, CAMBRIDGE, MA 02139

Aims and Scopes

The journal "Molecular Therapy Oncolytics" focuses on the innovative therapeutic strategies in oncology, particularly utilizing molecular and cellular approaches to enhance cancer treatment outcomes. It emphasizes the integration of cutting-edge technologies, including gene therapy, virotherapy, immunotherapy, and targeted therapies, to address various cancer types and their unique challenges.
  1. Oncolytic Virotherapy:
    Exploring the use of viruses engineered to selectively target and destroy cancer cells while stimulating an immune response against tumors.
  2. Gene Therapy:
    Investigating the application of gene editing technologies, such as CRISPR, to correct genetic defects in cancer cells or to introduce therapeutic genes to enhance anti-tumor immunity.
  3. Immunotherapy:
    Focusing on strategies that harness the body’s immune system to fight cancer, including CAR-T cell therapy, immune checkpoint inhibitors, and the use of immune modulators.
  4. Targeted Therapies:
    Developing treatments that specifically target molecular pathways involved in cancer progression, such as receptor tyrosine kinases and metabolic pathways.
  5. Tumor Microenvironment Interactions:
    Studying how the tumor microenvironment influences cancer progression and therapy response, and exploring ways to modify it to improve therapeutic efficacy.
  6. Extracellular Vesicles and Biomarkers:
    Investigating the role of exosomes and other extracellular vesicles in cancer biology and their potential as biomarkers for diagnosis and treatment monitoring.
The landscape of cancer research within "Molecular Therapy Oncolytics" is rapidly evolving, with emerging themes reflecting the latest advancements and interests in the field. These trends highlight the journal's commitment to addressing contemporary challenges in cancer therapy.
  1. Combination Immunotherapy:
    There is a growing trend towards combining different immunotherapeutic approaches, such as CAR-T cells with immune checkpoint inhibitors, to enhance treatment efficacy and overcome resistance.
  2. Oncolytic Virus Engineering:
    Research on the engineering of oncolytic viruses to improve their specificity and efficacy against various cancers is gaining traction, reflecting the innovative strategies being developed in virotherapy.
  3. MicroRNA and Non-Coding RNA Therapies:
    The exploration of microRNAs and other non-coding RNAs as therapeutic targets or agents is emerging, indicating a shift towards understanding gene regulation in cancer.
  4. Personalized Medicine Approaches:
    There is an increasing focus on personalized medicine, where treatments are tailored based on individual tumor genetics and patient profiles, leading to improved patient outcomes.
  5. Tumor Microenvironment Modulation:
    Research is trending towards strategies that target the tumor microenvironment to enhance drug delivery and immune response, emphasizing the complexity of tumor biology.

Declining or Waning

While "Molecular Therapy Oncolytics" has shown a strong focus on various innovative cancer therapies, certain areas of research appear to be declining in prominence. This reflects the evolving nature of cancer research and the journal's adaptation to new scientific insights and technological advancements.
  1. Conventional Chemotherapy:
    Research focusing solely on traditional chemotherapy methods has become less prevalent, as the field shifts towards more personalized and targeted treatment strategies.
  2. Single-Agent Therapies:
    Studies that emphasize the use of single-agent therapies without combining them with immunotherapy or other modalities are declining, as combination therapies are increasingly recognized as more effective.
  3. Basic Mechanistic Studies:
    There is a waning interest in purely mechanistic studies that do not translate into therapeutic applications, as the journal prioritizes research with direct clinical relevance.
  4. Animal Models with Limited Relevance:
    Research utilizing outdated or poorly characterized animal models that do not accurately represent human cancer biology is less frequently published, in favor of studies with more translational value.

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